Results 171 to 180 of about 2,904,339 (217)

Lipid metabolism reprogramming shapes the immune landscape in the tumor microenvironment. [PDF]

open access: yesCell Mol Immunol
Du YW   +7 more
europepmc   +1 more source

(24S)-Hydroxycholesterol efflux from neuronal cells by ABC proteins

open access: yes(24S)-Hydroxycholesterol efflux from neuronal cells by ABC proteins
openaire  

25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Cholesterol is responsible for the plasticity of plasma membranes and is involved in physiological and pathophysiological responses. Cholesterol homeostasis is regulated by oxysterols, such as 25-hydroxycholesterol.
Marco M Domingues   +2 more
exaly   +2 more sources

24S-Hydroxycholesterol: a Marker of Brain Cholesterol Metabolism

Pharmacopsychiatry, 2003
The enzymatic conversion of CNS cholesterol to 24S-hydroxycholesterol, which readily crosses the blood-brain barrier, is the major pathway for brain cholesterol elimination and brain cholesterol homeostasis maintenance. The enzyme mediating this conversion has been characterized at the molecular level (CYP46) and is mainly located in neurons.
D, Lütjohann, K, von Bergmann
openaire   +2 more sources

Degradation of 24S-hydroxycholesterol in men is not regulated by CYP7A1

Int. Journal of Clinical Pharmacology and Therapeutics, 2007
The conversion of cholesterol into bile acids occurs via a long cascade of enzymatically regulated oxidative processes. Our aim was to examine if an up-regulation of hepatic cholesterol 7alpha-hydroxylase (CYP7A1) in humans by cholestyramine, a bile acid-binding resin, has an effect on the degradation of brain-specific 24S-hydroxycholesterol.Six ...
C, Knabe   +3 more
openaire   +2 more sources

Plasma 24S-hydroxycholesterol

NeuroReport, 2000
The conversion of brain cholesterol into 24S-hydroxycholesterol and its subsequent release into the periphery is probably an important step for the maintenance of brain cholesterol homeostasis. Recent findings suggest that plasma 24S-hydroxycholesterol may be elevated in Alzheimer's disease (AD) and vascular dementia at least at some stage of the ...
Papassotiropoulos, A.   +9 more
openaire   +2 more sources

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