Results 201 to 210 of about 13,032 (223)

Neuron survival modulated by 24-hydroxycholesterol: the role of sirtuin pathway in Alzheimer's Disease

Free Radical Biology and Medicine, 2016
Alzheimer’s disease (AD) is a devastating neurodegenerative condition typified by the pathological accumulation of amyloid β peptides and neurofibrillary tangles of hyperphosphorylated Tau protein within the brain. Moreover, Tau acetylation is abnormally high in the brains of AD patients, even in the early stage of the disease.
GAMBA, Paola Francesca, TESTA, GABRIELLA, STAURENGHI, ERICA, GARGIULO, Simona, ROSSIN, DANIELA, POLI, Giuseppe, LEONARDUZZI, Gabriella Marisa   +6 more
openaire   +2 more sources

The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation

Immunity, 2021
Bruno C Trindade, Simona Ceglia, Alyssa Berthelette   +2 more
exaly  

Absolute configurations of 24-hydroxycholesterol and related compounds

Tetrahedron Letters, 1975
Naoyuki Koizumi, Masuo Morisaki, Nobuo Ikekawa, Atsuo Suzuki, Toru Takeshita   +4 more
openaire   +1 more source

Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases

Ageing Research Reviews, 2021
Atanas G Atanasov, John J Mackrill, P Andreoletti   +2 more
exaly  

24-Hydroxycholesterol 7α-hydroxylase

2009
openaire   +1 more source

24-hydroxycholesterol levels in human brain.

Journal of neurochemistry, 1972
L L, Smith, D R, Ray, J A, Moody, J D, Wells, J E, Van Lier   +4 more
openaire   +1 more source

27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

Science, 2013
Erik R Nelson, Suzanne E Wardell, Michihisa Umetani   +2 more
exaly  

Potentiation of amyloid-β-peptide neurotoxicity by 4-hydroxynonenal and 24-hydroxycholesterol

2012
Alzheimer’s disease (AD) is characterized by extracellular deposits of amyloid-β (Aβ) (senile plaques) and intracellular inclusions of hyperphosphorylated tau (neurofibrillary tangles). Moreover, intraneuronal Aβ plays a primary role in AD pathogenesis. A growing body of evidence suggests a link between lipid peroxidation and AD.
GAMBA, Paola Francesca, TESTA, GABRIELLA, GARGIULO, Simona, SOTTERO, Barbara, DI SCIPIO, FEDERICA, SPRIO, ANDREA ELIO, SALAMONE, PAOLINA, BERTA, Giovanni Nicolao, LEONARDUZZI, Gabriella Marisa, POLI, Giuseppe   +9 more
openaire   +1 more source

The Cholesterol Metabolite 27-Hydroxycholesterol Promotes Atherosclerosis via Proinflammatory Processes Mediated by Estrogen Receptor Alpha

Cell Metabolism, 2014
Michihisa Umetani, Chieko Mineo, Philip W Shaul   +2 more
exaly  

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model

Immunity, 2017
Chunfeng Li, Yong-Qiang Deng, Shuo Wang
exaly