Results 151 to 160 of about 88,507,977 (198)

Human Milk as a Model for Next-Generation Infant Formula: Opportunities and Challenges. [PDF]

Adv Nutr
Ryan MRB, Swackhamer C, Donovan SM, Smilowitz JT, Kim JH, Stewart CJ, Kuehn D, Rauner G, Hettinga K, Kearns ED, Smolen KK, Reyes SM, Rai GP, McGuire MK, Russo C, Dallas DC.   +15 more
europepmc   +1 more source

2′-Fucosyllactose and 3-Fucosyllactose Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Modulating the Intestinal Microbiome [PDF]

Nutrients, 2023
Ulcerative colitis is an inflammatory bowel disease (IBD) with relapsing and remitting patterns, and it is caused by varied factors, such as the intestinal inflammation extent and duration.
Young-Ha Song, Kwang-Youn Kim
exaly   +3 more sources

Quantifying the Human Milk Oligosaccharides 2’-Fucosyllactose and 3-Fucosyllactose in Different Food Applications by High-Performance Liquid Chromatography With Refractive Index Detection [PDF]

Journal of Food Science, 2020
Bettina Høj Hornshøj, Sara Eun Lendal
exaly   +2 more sources

Determination and Quantification of 2’-O-Fucosyllactose and 3-O-Fucosyllactose in Human Milk by GC–MS as O-Trimethylsilyl-Oxime Derivatives

Journal of Pharmaceutical and Biomedical Analysis, 2015
Human milk oligosaccharides possess various biological functions by protecting the infant from several bacterial and viral infections, modulating the immune system, serving as prebiotics and also contributing to the brain development.
Szabolcs Béni, Réka Balogh
exaly   +2 more sources

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Neonatal subchronic toxicity and in vitro genotoxicity studies of the human‐identical milk oligosaccharide 3‐fucosyllactose

Journal of Applied Toxicology, 2022
AbstractHuman milk oligosaccharides, such as 3‐fucosyllactose (3‐FL), are bioactive components of breast milk associated with benefits for infant growth and development. Structurally identical compounds (human‐identical milk oligosaccharides—HiMOs) can be produced using microbial fermentation, allowing their use in infant formula to increase its ...
Kirt R. Phipps, Dayna Lozon, Diane R. Stannard, Ben Gilby, Nigel Baldwin, Marta Hanna Mikš, Annette Lau, Christoph H. Röhrig   +7 more
openaire   +2 more sources

Engineering of α-1,3-Fucosyltransferases for Production of 3-Fucosyllactose in Escherichia coli

Metabolic Engineering, 2018
Fucosyllactoses (FLs), present in human breast milk, have been reported to benefit human health immensely. Especially, 3-fucosyllactose (3-FL) has numerous benefits associated with a healthy gut ecosystem. Metabolic engineering of microorganisms is thought to be currently the only option to provide an economically feasible route for large-scale ...
Jiwon Yu, Jonghyeok Shin, Jin-Ho Seo
exaly   +3 more sources

Metabolic Engineering of Escherichia coli for the Production of 2′-Fucosyllactose and 3-Fucosyllactose Through Modular Pathway Enhancement

Metabolic Engineering, 2017
Fucosyllactoses, including 2'-fucosyllactose (2'-FL) and 3-fucosyllactose (3-FL), are important oligosaccharides in human milk that are commonly used as nutritional additives in infant formula due to their biological functions, such as the promotion of bifidobacteria growth, inhibition of pathogen infection, and improvement of immune response.
Jia Liu, Di Huang, Ru Wang
exaly   +3 more sources

Recent advances of 3-fucosyllactose in health effects and production

Archives of Microbiology
Human milk oligosaccharides (HMOs) have been recognized as gold standard for infant development. 3-Fucosyllactose (3-FL), being one of the Generally Recognized as Safe HMOs, represents a core trisaccharide within the realm of HMOs; however, it has received comparatively less attention in contrast to extensively studied 2'-fucosyllactose.
Zhihui, Du, Zeyu, Li, Cuie, Guang, Yingying, Zhu, Wanmeng, Mu   +4 more
openaire   +2 more sources

Safety assessment of the biotechnologically produced human-identical milk oligosaccharide 3-Fucosyllactose (3-FL)

Food and Chemical Toxicology, 2019
3-Fucosyllactose (3-FL), a highly abundant complex carbohydrate in human breast milk, functions as a prebiotic promoting early microbial colonization of the gut, increasing pathogen resistance and modulating immune responses. To investigate potential health benefits, 3-FL was produced by fermentation using a genetically modified E. coli K12 strain. The
J. Pitt, M. Chan, C. Gibson, O. Hasselwander, A. Lim, P. Mukerji, R. Mukherjea, A. Myhre, P. Sarela, P. Tenning, M.W. Himmelstein, J.M. Roper   +11 more
openaire   +2 more sources

Safety Assessment: Outcome of the assessment of 3-fucosyllactose (3-FL) as a novel food

2023
The novel food is 3-FL which is intended to be used as a source of human identical milk oligosaccharides. 3-FL is manufactured by microbial fermentation using a genetically modified strain of Escherichia coli K-12, and then refined to yield the purified novel food.
openaire   +1 more source