Results 171 to 180 of about 88,507,977 (198)

3-Fucosyllactose Prevents Nonalcoholic Fatty Liver Disease by Modulating the Gut Microbiota-Derived Pantothenate in Mice

Journal of Agricultural and Food Chemistry
Nonalcoholic fatty liver disease (NAFLD) is a growing global health threat. Human milk oligosaccharides (HMOs) exhibit prebiotic properties that may alleviate NAFLD progression. Herein, our study demonstrates that 3-fucosyllactose (3-FL), a distinctive and crucial HMO, significantly attenuates body weight gain, enhances hepatic lipid metabolism, and ...
Bei Liu, Ningning He, Hui Li, Zizhen Yang, Yichen Lin, Xiaoyu Wu, Haoyan Zhang, Ziheng Zhang, Zishuai Zhang, Yu Tian, Zhinan Wu, Yuanqiang Zou, Jixing Peng, Shangyong Li   +13 more
openaire   +2 more sources

Harnessing 3-Fucosyllactose: Dynamic Regulation Unlocks Efficient l -fucose Production in Escherichia coli

Journal of Agricultural and Food Chemistry
l-fucose, a key component of human milk oligosaccharides, which affects the intestinal health and immune development of infants and is widely used in infant formula food, functional food and nutritional supplements. To enable efficient and sustainable biosynthesis, we developed a novel synthetic route using 3-fucosyllactose as a precursor and employed ...
Jing Cao, Zhiqiang Huang, Caiwen Lao, Jianming Yao, Lixia Yuan, Jinyong Wu, Xiangsong Chen   +6 more
openaire   +2 more sources

The combination of human milk oligosaccharides 3-fucosyllactose and 3′-sialyllactose alleviates LPS-induced damage to intestinal epithelial cells

Food & Function
The combination of 3-fucosyllactose (3-FL) and 3′-sialyllactose(3′-SL) alleviated LPS-induced IEC-6 cell damage by inhibiting the TLR4/NF-κB pathway, promoting the Nrf2/NQO1 pathway, and enhancing intercellular tight junctions.
Xianhui, Chen, Hao, Shi, Mingzhang, Zhao, Zhanmei, Jiang, Jiahui, Guo, Jing, Zhang, Xiaolei, Duan, He, Zhang, Juncai, Hou, Xiangyu, Li   +9 more
openaire   +2 more sources

Synthesis of Human Milk Oligosaccharides: 2'- and 3'-Fucosyllactose

HETEROCYCLES, 2012
Frank E. McDonald, Claney L. Pereira
openaire   +1 more source

De Novo Biosynthesis of 2′-Fucosyllactose in a Metabolically Engineered Escherichia coli Using a Novel ɑ1,2-Fucosyltransferase From Azospirillum Lipoferum

Bioresource Technology, 2023
Wanmeng Mu, Wenli Zhang, Yingying Zhu
exaly  

Recent Advances on 2′-Fucosyllactose: Physiological Properties, Applications, and Production Approaches

Critical Reviews in Food Science and Nutrition, 2022
Wanmeng Mu, Dawei Ni, Xin Yan
exaly  

Enhanced 2′-Fucosyllactose Production by Engineered Saccharomyces cerevisiae Using Xylose as a Co-Substrate

Metabolic Engineering, 2020
Jing-Jing Liu, Yong-Su Jin
exaly  

Weighted Analysis of 2′-Fucosyllactose, 3-Fucosyllactose, Lacto-N-Tetraose, 3′-Sialyllactose, and 6′-Sialyllactose Concentrations in Human Milk

Food and Chemical Toxicology, 2022
Robert Lodder, Katja Parschat
exaly  

2′-Fucosyllactose/3-Fucosyllactose

Luyao Wang, Shengqi Gao, Kang Zhang, Jing Wu   +3 more
openaire   +1 more source

PRODUCTION OF 3-FUCOSYLLACTOSE AND LACTOSE CONVERTING α-1,3-FUCOSYLTRANSFERASE ENZYMES

2020
BEAUPREZ JOERI, LANNOO NAUSICAÄ, VANDEWALLE KRISTOF, VERCAUTEREN ANNELIES   +3 more
openaire   +3 more sources