Results 11 to 20 of about 88,507,977 (198)

Safety of the extension of use of 3‐fucosyllactose (3‐FL) as a novel food pursuant to Regulation (EU) 2015/2283 [PDF]

EFSA Journal
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of the extension of use of 3‐fucosyllactose (3‐FL) as a novel food (NF) pursuant to ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Harry J. McArdle, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Helle Katrine Knutsen, Monika Neuhäuser‐Berthold, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Estefanía Noriega Fernández, Paolo Colombo, Karen Ildico Hirsch‐Ernst   +28 more
doaj   +9 more sources

Occurrence, functional properties, and preparation of 3-fucosyllactose, one of the smallest human milk oligosaccharides

Critical Reviews in Food Science and Nutrition, 2022
Human milk oligosaccharides (HMOs) are receiving wide interest and high attention due to their health benefits, especially for newborns. The HMOs-fortified products are expected to mimic human milk not only in the kinds of added oligosaccharides components but also the appropriate proportion between these components, and further provide the nutrition ...
Zeyu Li, Yingying Zhu, Dawei Ni, Wenli Zhang, Wanmeng Mu   +4 more
openaire   +3 more sources

Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2′-Fucosyllactose and 3-Fucosyllactose [PDF]

Journal of Innate Immunity, 2022
Allergic sensitization starts with epithelial cell activation driving dendritic cells (DCs) to instruct T helper 2 (Th2) cell polarization. Food allergens trigger intestinal epithelial cell (IEC) activation.
Marit Zuurveld, Pien C.J. Kiliaan, Sophie E.L. van Grinsven, Gert Folkerts, Johan Garssen, Belinda van’t Land, Linette E.M. Willemsen   +6 more
doaj   +2 more sources

Strain-specific strategies of 2′-fucosyllactose, 3-fucosyllactose, and difucosyllactose assimilation by Bifidobacterium longum subsp. infantis Bi-26 and ATCC 15697 [PDF]

Scientific Reports, 2020
Human milk provides essential nutrients for infant nutrition. A large proportion of human milk is composed of human milk oligosaccharides (HMOs), which are resistant to digestion by the infant. Instead, HMOs act as a bioactive and prebiotic enriching HMO-
Bryan E. Zabel, Svetlana Gerdes, Kara C. Evans, Derek Nedveck, Suzanne Koch Singles, Barbara Volk, Charles Budinoff   +6 more
doaj   +2 more sources

Chemical Synthesis of Two Fucosylated Human Milk Oligosaccharides: 3‐Fucosyllactose and Lacto‐N‐fucopentaose V [PDF]

Chemistry – A European Journal
AbstractGlycans present in human milk have been the focus of many studies due to challenges associated with their synthesis. The development of new methods for obtaining individual glycans found in human milk has been a vibrant area of research in glycosciences.
Faranak Pooladian, Anupama Das, Alexei V. Demchenko   +2 more
openaire   +4 more sources

Research Progress in Metabolic Engineering Strategies for Microbial Synthesis of 2′-Fucosyllactose and 3-Fucosyllactose

Shipin gongye ke-ji
Human milk oligosaccharides (HMOs) are key components of breast milk, playing a vital role in fostering the healthy development of infants and young children.
Dengbin LI, Chao WEI, Yuan ZHANG, Genlin ZHANG, Xiaoyan WANG   +4 more
doaj   +2 more sources

Metabolic Engineering of Escherichia coli to Synthesize 3-Fucosyllactose via the Salvage Pathway [PDF]

Shipin Kexue
3-Fucosyllactose (3-FL) is a typical human milk oligosaccharides (HMOs) and plays a significant physiological function in the growth and brain development of infants.
LIANG Shanquan, HE Zi, JIANG Zhengqiang, YANG Shaoqing
doaj   +2 more sources

Safety of 2′‐fucosyllactose (2’‐FL) produced by a derivative strain (APC199) of Corynebacterium glutamicum ATCC 13032 as a novel food pursuant to Regulation (EU) 2015/2283 [PDF]

EFSA Journal, 2022
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 2′‐fucosyllactose (2’‐FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Alexandre Maciuk, Inge Mangelsdorf, Harry J. McArdle, Androniki Naska, Carmen Pelaez, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Rosangela Marchelli, Monika Neuhäuser‐Berthold, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Henk vanLoveren, Paolo Colombo, Estefanía Noriega Fernández, Helle Katrine Knutsen   +27 more
doaj   +4 more sources

Transglycosylation Capabilities of Wild‐Type α‐l‐Fucosidase iso1 from Paenibacillus thiaminolyticus and Its Engineered Mutants: Preparation of Fucosylated Oligosaccharides [PDF]

Microbial Biotechnology
To enhance the yield of l‐fucosylated molecules synthesized via transfucosylation, we employed α‐l‐transfucosidases, enzymes engineered from α‐l‐fucosidases to favour transglycosylation over hydrolysis.
Patricie Vodičková, Lucie Klimešová, Pavlína Nekvasilová, Lucie Petrásková, Helena Pelantová, Terézia Kovaľová, Petra Lipovová, Pavla Bojarová, Eva Benešová   +8 more
doaj   +2 more sources

The synergies effect of 3′-sialyllactose and 2′-fucosyllactose on the attenuation of food allergy symptoms in a mouse model [PDF]

Food Science of Animal Products
The functional components known as milk oligosaccharides are crucial in the milk of diverse animals. Increasing evidence of immunomodulatory effects of milk oligosaccharides suggests that they may have some therapeutic potential in allergy.
Lina Zhang, Qiaran Lin, Yue Shi, Tong Liu, Peng Zhou   +4 more
doaj   +2 more sources