Urinary levels of kynurenine and 3-hydroxykynurenine in the rat: Effects of triamterene
Biochemical and Biophysical Research Communications, 1970Abstract In a 24-hour period after injection of 7.35 millimoles of tryptophan into rats intraperitoneally, 450 μmoles of kynurenine and 210 μmoles of 3-hydroxykynurenine were excreted. This accounts for 6.2% and 2.9% respectively of the injected tryptophan.
D, Ghosh, R, Green
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Chemotaxonomy and Chemomimicry: The Case of 3-Hydroxykynurenine
Systematic Zoology, 1967The distributional data for the metabolic amino acid 3-hydroxy-L-kynurenine as a wing pigment in nymphalid butterflies would suggest taxonomic groupings essentially in contradiction with those resulting from more broad-scale morphological, breeding and behavioral studies; this indicates that the storage of this pigment is a taxonomically relatively ...
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Distribution of [3H]-3-hydroxykynurenine in mice.
Cancer research, 1976The distribution of 3-hydroxykynurenine, a tryptophan metabolite that is suspected of being carcinogenic, was studied in mice. After s.c. administration of [3H]-3-hydroxykynurenine into male BALB/c X DBA/2 F1 mice, the distribution of 3H was investigated by whole-body autoradiography and radioactivity measurement.
Watanabe, M, Sugimori, Y
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Mutagenic Effect of 3-Hydroxykynurenine and 3-Hydroxyanthranilic Acid
Nature, 1969MANY metabolites of tryptophane found in the urine of patients with leukaemia1,2 and bladder tumours3–12 induce tumours in experimental animals13–16.
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Isolation of Kynurenine and 3-Hydroxykynurenine from Human Pathological Urine
Nature, 1955IN 1951, 3-hydroxyanthranilic acid was isolated from the urine of a patient with pulmonary tuberculosis after administration of 1-tryptophan1. This result caused us to examine the urine of various subjects, including some tuberculous patients not receiving special diet or supplementary administration of tryptophan.
L, MUSAJO, C A, BENASSI, A, PARPAJOLA
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ChemInform Abstract: Oxidation of 3‐Hydroxykynurenine. An EPR Investigation.
ChemInform, 1991AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. BOLOGNESE +3 more
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Elucidation of a Novel Polypeptide Cross-Link Involving 3-Hydroxykynurenine
Biochemistry, 19993-Hydroxykynurenine, a metabolite of tryptophan, is a powerful antioxidant and neurotoxin. The neurotoxicity results from the oxidation of 3-hydroxykynurenine, and hydroxyl radicals, formed via H(2)O(2), may also be implicated [Okuda, S., Nishiyama, N., Saito, H. , and Katsuki, H. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 12553-12558].
J A, Aquilina +2 more
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Enzymatic assay of kynurenine and 3-hydroxykynurenine with neurospora or pseudomonas kynureninase
Clinica Chimica Acta, 1973Abstract A method is described for the analysis of kynurenine and 3-hydroxykynurenine in biological samples, in particular urine, by use of kynureninase isolated from either Neurospora crassa or Pseudomonas fluorescens . The method is based on the enzymatic conversion of these two metabolites to anthranilic and 3-hydroxyanthranilic acid ...
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Conversion of Kynurenine into 3-Hydroxykynurenine in Man
Science, 1954K, MAKINO, K, ARAI, S, OKA
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Estimation of the tryptophan metabolites xanthurenic acid, 3-hydroxykynurenine and kynurenine
Clinica Chimica Acta, 1967Abstract Colorimetric methods for estimating xanthurenic acid and 3-hydroxykynurenine by their reaction with diazotized sulphanilic acid have been investigated. Modification of these methods eliminates the difficulties previously found in estimating these metabolites. A covering layer of butanol is used to prevent atmospheric oxidation of the colours.
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