Results 61 to 70 of about 5,596 (203)
Neurobiology of Disease, 2006 Pneumococcal meningitis (PM) is characterized by an intense inflammatory host reaction that contributes to the development of cortical necrosis and hippocampal apoptosis.
Caroline L. Bellac +3 more
doaj +1 more source
Detoxification and stress response genes expressed in a western North American bumble bee, Bombus huntii (Hymenoptera: Apidae) [PDF]
, 2013 BACKGROUND: The Hunt bumble bee (Bombus huntii Greene, Hymenoptera: Apidae) is a holometabolous, social insect important as a pollinator in natural and agricultural ecosystems in western North America.
Dennis L Welker +3 more
core +1 more source
The Journal of Dermatology, Volume 53, Issue 6, Page 867-879, June 2026.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji +7 more
wiley +1 more source
Animals, 2021 Ketosis metabolic research on lactating dairy cattle has been conducted worldwide; however, there have been very few Korean studies. Biofluids from lactating dairy cattle are necessary to study ketosis metabolic diseases.
Jun-Sik Eom +8 more
doaj +1 more source
Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase [PDF]
Proceedings of the National Academy of Sciences, 2006 In Anopheles gambiae , the vector for the most deadly malaria parasite Plasmodium falciparum , xanthurenic acid (XA) plays a key role in parasite gametogenesis and fertility. In mosquitoes, XA is produced by transamination of 3-hydroxykynurenine (3-HK), a reaction that represents the main ...
F. Rossi +5 more
openaire +5 more sources
Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect
Journal of Child Psychology and Psychiatry, Volume 67, Issue 6, Page 816-831, June 2026.Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson +4 more
wiley +1 more source
Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma
Antioxidants, 2022 Kynurenine 3-monooxygenase (KMO), a key player in the kynurenine pathway (KP) of tryptophan degradation, regulates the synthesis of the neuroactive metabolites 3-hydroxykynurenine (3-HK) and kynurenic acid (KYNA).
Korrapati V. Sathyasaikumar +10 more
doaj +1 more source
Role of lipid peroxidation in pathogenesis of senile cataract [PDF]
, 2009 Background /Aim. Cataract is a structural, biochemical and optical change in the eye lens, which changes transmission and refraction of light rays reducing keenness and clarity of a figure on the retina.
Dragojević Ilija +4 more
core +1 more source
Plasma Processes and Polymers, Volume 23, Issue 5, May 2026.A schematic showing the plasma device producing RONS into water, PTW applied to chickpea and mung bean seedlings, and resulting effects: (1) increased root growth and (2) detection of specific oxidative protein markers using LC‐MS/MS. ABSTRACT Plasma‐treated water (PTW) is a promising sustainable agricultural resource, yet its effects on seedling ...
Mohammad Bayati +2 more
wiley +1 more source
Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis [PDF]
, 2017 Recently, we reported a novel role for KMO in the pathogenesis of acute pancreatitis (AP). A number of inhibitors of kynurenine 3-monooxygenase (KMO) have previously been described as potential treatments for neurodegenerative conditions and particularly
Alexis Denis +21 more
core +1 more source