Results 31 to 40 of about 109,316 (244)
Three‐dimensional genome structure and function
MedComm, 2023 Linear DNA undergoes a series of compression and folding events, forming various three‐dimensional (3D) structural units in mammalian cells, including chromosomal territory, compartment, topologically associating domain, and chromatin loop.
Hao Liu +7 more
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Lamin C is required to establish genome organization after mitosis
Genome Biology, 2021 Background The dynamic 3D organization of the genome is central to gene regulation and development. The nuclear lamina influences genome organization through the tethering of lamina-associated domains (LADs) to the nuclear periphery.
Xianrong Wong +5 more
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Erratum: Organization and function of the 3D genome [PDF]
Nature Reviews Genetics, 2016 Nature Reviews Genetics 17, 661–678 (2016) In the original version of this article, the statement that CCCTC-binding factor (CTCF) is conserved in most bilaterians was incorrectly referenced. Reference 58 has now been corrected in the online version of the article to cite Heger, P., Marin, B., Bartkuhn, M.
Boyan Bonev, Giacomo Cavalli
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Comparative 3D genome architecture in vertebrates
BMC Biology, 2022 Background The three-dimensional (3D) architecture of the genome has a highly ordered and hierarchical nature, which influences the regulation of essential nuclear processes at the basis of gene expression, such as gene transcription.
Diyan Li +15 more
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Non-Coding RNA, 2022 This study explored the relationship between 3D genome organization and RNA–DNA triplex-forming sites of long noncoding RNAs (lncRNAs), a group of RNAs that do not code for proteins but are important factors regulating different aspects of genome ...
Benjamin Soibam
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Role of lamins in 3D genome organization and global gene expression
Nucleus, 2019 Genome-wide mapping of lamin-B1-genome interactions has shown that gene-poor and transcriptionally inactive genomic regions are associated with the nuclear lamina.
Youngjo Kim, Xiaobin Zheng, Yixian Zheng
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Machine and Deep Learning Methods for Predicting 3D Genome Organization. [PDF]
Methods Mol BiolSystematic review, one figure, three tables, 29 ...
Wall BPG +3 more
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Communications Biology, 2021 Kei Fukuda et al. show that the formation of chromatin domains marked by dimethylated H3K9 is functionally linked to the 3D organization of the genome.
Kei Fukuda +7 more
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Integrative studies of 3D genome organization and chromatin structure
Current Opinion in Structural Biology, 2022 The structural organization of the genome is emerging as a crucial regulator of the cell state, affecting gene transcription, DNA replication, and repair. Over the last twenty years, increasing evidence prompted the development of new experimental techniques to study genome structure.
Marco Di Stefano, Giacomo Cavalli
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PLoS Genetics, 2020 Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Yuh Chwen G Lee +7 more
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