Results 51 to 60 of about 5,043,774 (177)
Non-Coding RNA, 2022 This study explored the relationship between 3D genome organization and RNA–DNA triplex-forming sites of long noncoding RNAs (lncRNAs), a group of RNAs that do not code for proteins but are important factors regulating different aspects of genome ...
Benjamin Soibam
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The Relationship Between 3d Genome Organization And Uv-Induced Dna Damage And Repair [PDF]
, 2023 The three-dimensional (3D) configuration of the eukaryotic genome is essential for myriad cellular processes, such as the modulation of gene expression and the orchestration of epigenetic regulation, as well as the preservation of genome integrity ...
Akköse, Ümit
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Integrative studies of 3D genome organization and chromatin structure
Current Opinion in Structural Biology, 2022 The structural organization of the genome is emerging as a crucial regulator of the cell state, affecting gene transcription, DNA replication, and repair. Over the last twenty years, increasing evidence prompted the development of new experimental techniques to study genome structure.
Di Stefano, Marco, Cavalli, Giacomo
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EPIGENETIC DETERMINANTS OF HETEROCHROMATIC 3D GENOME ORGANIZATION [PDF]
The role of DNA positioning in three-dimensional (3D) space as a regulator of gene expression and genome function is an open area of investigation. Prior studies have reported correlations between chromatin states and 3D genome organization; however, the
Stutzman, Alexis Victoria
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Communications Biology, 2021 Kei Fukuda et al. show that the formation of chromatin domains marked by dimethylated H3K9 is functionally linked to the 3D organization of the genome.
Kei Fukuda +7 more
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Computational Methods for Multi-Species Comparison of 3D Genome Organization and Function
, 2023 Recent developments in chromatin interaction mapping technologies have greatly advanced the study of higher-order genome organization in the three-dimensional (3D) cell nucleus, which is of vital importance to fundamental genome functions such as DNA ...
Yang Yang (4935544)
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Machine and Deep Learning Methods for Predicting 3D Genome Organization. [PDF]
Methods Mol BiolSystematic review, one figure, three tables, 29 ...
Wall BPG +3 more
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PLoS Genetics, 2020 Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Yuh Chwen G Lee +7 more
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Open for connections: HiCAR reveals the interactions of accessible DNA
Cell Genomics, 2022 Hi-C is a powerful technology for exploring 3D genome organization on a genome-wide scale, yet it can be financially and computationally challenging. In a recent issue of Molecular Cell, Wei et al.1 introduce HiCAR, which simplifies Hi-C by targeting the
Benoit Moindrot, Daan Noordermeer
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3D nuclear organization and genomic instability in cancer [PDF]
BMC Proceedings, 2013 To understand the genetic changes that occur at tumor initiation and during tumor progression, we focus on changes in nuclear architecture that promote the onset of genomic instability [1,2]. To determine changes in nuclear organization, we measure the 3D nuclear organization of telomeres, the ends of chromosomes.
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