Results 41 to 50 of about 110,305 (278)

The impact factors of 3D genome organization [PDF]

open access: yesSCIENTIA SINICA Vitae, 2020
The 3D architecture of chromosomes is involved in the precision regulation of gene expression, and the changes in spatial conformation of chromosomes, accordingly, influence the biological processes in a cell. Recent findings in 3D genomics, through technological advances in approaches combining chromosome conformation capture (3C) and DNA sequencing ...
YiXian FAN, XiaoYi HANG, XiMiao HE
openaire   +1 more source

Three‐dimensional genome structure and function

open access: yesMedComm, 2023
Linear DNA undergoes a series of compression and folding events, forming various three‐dimensional (3D) structural units in mammalian cells, including chromosomal territory, compartment, topologically associating domain, and chromatin loop.
Hao Liu   +7 more
doaj   +1 more source

Lamin C is required to establish genome organization after mitosis

open access: yesGenome Biology, 2021
Background The dynamic 3D organization of the genome is central to gene regulation and development. The nuclear lamina influences genome organization through the tethering of lamina-associated domains (LADs) to the nuclear periphery.
Xianrong Wong   +5 more
doaj   +1 more source

Allele-specific control of replication timing and genome organization during development [PDF]

open access: yes, 2018
DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional activity and 3D genome organization.
Dimond, AM
core   +1 more source

Comparative 3D genome architecture in vertebrates

open access: yesBMC Biology, 2022
Background The three-dimensional (3D) architecture of the genome has a highly ordered and hierarchical nature, which influences the regulation of essential nuclear processes at the basis of gene expression, such as gene transcription.
Diyan Li   +15 more
doaj   +1 more source

Association between Triplex-Forming Sites of Cardiac Long Noncoding RNA GATA6-AS1 and Chromatin Organization

open access: yesNon-Coding RNA, 2022
This study explored the relationship between 3D genome organization and RNA–DNA triplex-forming sites of long noncoding RNAs (lncRNAs), a group of RNAs that do not code for proteins but are important factors regulating different aspects of genome ...
Benjamin Soibam
doaj   +1 more source

Principles of the 3D genome organization in malaria mosquitoes

open access: yes, 2020
Poster "Principles of the 3D genome organization in malaria mosquitoes.
Varvara Lukyanchikova (8713636)   +6 more
core   +1 more source

Erratum: Organization and function of the 3D genome [PDF]

open access: yesNature Reviews Genetics, 2016
Nature Reviews Genetics 17, 661–678 (2016) In the original version of this article, the statement that CCCTC-binding factor (CTCF) is conserved in most bilaterians was incorrectly referenced. Reference 58 has now been corrected in the online version of the article to cite Heger, P., Marin, B., Bartkuhn, M.
Boyan Bonev, Giacomo Cavalli
openaire   +1 more source

Role of lamins in 3D genome organization and global gene expression

open access: yesNucleus, 2019
Genome-wide mapping of lamin-B1-genome interactions has shown that gene-poor and transcriptionally inactive genomic regions are associated with the nuclear lamina.
Youngjo Kim, Xiaobin Zheng, Yixian Zheng
doaj   +1 more source

Machine and Deep Learning Methods for Predicting 3D Genome Organization. [PDF]

open access: yesMethods Mol Biol
Systematic review, one figure, three tables, 29 ...
Wall BPG   +3 more
europepmc   +5 more sources

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