Results 11 to 20 of about 259,851 (238)

3T3-L1 adipocytes display phenotypic characteristics of multiple adipocyte lineages [PDF]

Adipocyte, 2015
Differentiated 3T3-L1 adipocytes are a widely used in vitro model of white adipocytes. In addition to classical white and brown adipocytes that are derived from different cell lineages, beige adipocytes have also been identified, which have characteristics of both white and brown adipocytes.
Shona, Morrison, Sean L, McGee
openaire   +3 more sources

Phosphatidylcholine induces apoptosis of 3T3-L1 adipocytes [PDF]

Journal of Biomedical Science, 2011
Abstract Background Phosphatidylcholine (PPC) formulation is used for lipolytic injection, even though its mechanism of action is not well understood. Methods The viability of 3T3-L1 pre-adipocytes and differentiated 3T3-L1 cells was measured after treatment of PPC alone ...
Li Hailan, Lee Jong-Hyuk, Kim Su Yeon, Yun Hye-Young, Baek Kwang Jin, Kwon Nyoun Soo, Yoon Yoosik, Jeong Ji Hoon, Kim Dong-Seok   +8 more
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Differentiation of 3T3‐L1 Fibroblasts Into Adipocytes [PDF]

Current Protocols
Abstract Obesity and type 2 diabetes (T2D) have reached epidemic proportions worldwide, affecting millions of people and contributing to serious health complications, such as metabolic syndrome, cardiovascular disease, and cancer.
Jones, William J., Couper, Rhea, Gould, Gwyn W., Bryant, Nia J.   +3 more
openaire   +4 more sources

Temperature induced modulation of lipid oxidation and lipid accumulation in palmitate-mediated 3T3-L1 adipocytes and 3T3-L1 adipocytes

Journal of Thermal Biology, 2016
Human skin temperature can vary widely depending on anatomical location and ambient temperature. It is also known that local changes in skin and subcutaneous temperature can affect fat metabolism. This study aimed to explore the potential effects of surrounding thermal environment on fat by investigating cell viability, lipid oxidation, and lipid ...
Lin, Xiaofen, Li, Yi, Leung, Polly Hangmei, Li, Jiashen, Hu, Junyan, Liu, Xuan, Li, Zhi   +6 more
openaire   +5 more sources

The 3T3-L1 adipocyte glycogen proteome [PDF]

Proteome Science, 2013
Abstract Background Glycogen is a branched polysaccharide of glucose residues, consisting of α-1-4 glycosidic linkages with α-1-6 branches that together form multi-layered particles ranging in size from 30 nm to 300 nm.
Stapleton, D, Nelson, C, Parsawar, K, Flores-Opazo, M, McClain, D, Parker, G   +5 more
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Development of Insulin Resistance in 3T3-L1 Adipocytes [PDF]

Journal of Biological Chemistry, 1997
Insulin resistance is a manifestation of both diabetes mellitus and obesity. However, the mechanism is still not clearly identified. Herein, we describe a procedure that allows us to evaluate the development of insulin resistance in 3T3-L1 adipocytes. Under these conditions, we show that the concentration of insulin required for 50% desensitization of ...
M J, Thomson, M G, Williams, S C, Frost
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RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

MicroRNA and 3T3-L1 pre-adipocyte differentiation [PDF]

RNA, 2006
MicroRNAs (miRNAs) have been suggested to play important roles in cell proliferation, apoptosis, and differentiation. In this study, we examined miRNA expression profiles during 3T3-L1 pre-adipocyte differentiation. We constructed miRNA libraries from pre- and post-differentiated 3T3-L1 cells, and identified the expression of 77 previously reported ...
Kazuaki, Kajimoto, Hiroaki, Naraba, Naoharu, Iwai   +2 more
openaire   +2 more sources

Oleate induces apoptosis in 3T3-L1 adipocytes [PDF]

, 2011
Oleic acid (C18:1) play an important role in proliferation of fat cells. In this study, the effect of oleate on cells viability in 3T3-L1 cells (fat cells) was investigated.
Rohana, Abu, Muhammad Roji, M. S., Fadzilah Adibah, A. M.   +2 more
core   +2 more sources

Spermidine is indispensable in differentiation of 3T3‐L1 fibroblasts to adipocytes [PDF]

Journal of Cellular and Molecular Medicine, 2010
AbstractImpaired adipogenesis has been shown to predispose to disturbed adipocyte function and development of metabolic abnormalities. Previous studies indicate that polyamines are essential in the adipogenesis in 3T3‐L1 fibroblasts. However, the specific roles of individual polyamines during adipogenesis have remained ambiguous as the natural ...
Vuohelainen, Susanna, Pirinen, Eija, Cerrada-Gimenez, Marc, Keinänen, Tuomo A., Uimari, Anne, Pietilä, Marko, Khomutov, Alex R., Jänne, Juhani, Alhonen, Leena   +8 more
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