Results 31 to 40 of about 259,851 (238)
Increased Oxidative Stress in Cultured 3T3-L1 Cells was Attenuated by Berberine Treatment
The 3T3-L1 cell line is one of the most well-characterized and reliable models for studying adipocytes. Increased oxidative stress in accumulated fat was found in 3T3-L1 cells.
Shi-Fen Dong +5 more
doaj +1 more source
Conflicting results for morusin activity during adipogenic differentiation are reported in 3T3-L1 adipocytes and cancer cells. To elucidate the influence of morusin on fat metabolism, their anti-obesity effects and molecular mechanism were investigated ...
Mi Rim Lee +10 more
doaj +1 more source
Effect of Cucumis sativus on Dysfunctional 3T3-L1 Adipocytes [PDF]
AbstractObesity is caused by lipid accumulation in adipose tissues inducing adipocyte dysfunction, characterized by insulin resistance, increased lipolysis, oxidative stress, and inflammation, leading to increased levels of adipokines. Herein the capacity of the subfractions (SFs) SF1, SF2, and SF3 from theCucumis sativusaqueous fraction and their ...
Marisol Méndez-Martínez +13 more
openaire +2 more sources
Insulin-responsive Aminopeptidase Trafficking in 3T3-L1 Adipocytes [PDF]
The insulin-responsive aminopeptidase (IRAP/VP165/gp160) was identified originally in GLUT4-containing vesicles and shown to translocate in response to insulin, much like the glucose transporter 4 (GLUT4). This study characterizes the trafficking and kinetics of IRAP in exocytosis, endocytosis, and recycling to the membrane in 3T3-L1 adipocytes.
L A, Garza, M J, Birnbaum
openaire +2 more sources
TC10 Is Regulated by Caveolin in 3T3-L1 Adipocytes
TC10 is a small GTPase found in lipid raft microdomains of adipocytes. The protein undergoes activation in response to insulin, and plays a key role in the regulation of glucose uptake by the hormone.TC10 requires high concentrations of magnesium in order to stabilize guanine nucleotide binding.
Dave Bridges +4 more
openaire +4 more sources
Effect of Crocetin on Basal Lipolysis in 3T3-L1 Adipocytes
Crocetin (CCT) is a natural saffron-derived apocarotenoid that possesses healthy properties such as anti-adipogenic, anti-inflammatory, and antioxidant activities. Lipolysis is enhanced in obesity and correlates with a pro-inflammatory, pro-oxidant state. In this context, we aimed to investigate whether CCT affects lipolysis. To evaluate CCT’s possible
Francisco J. Cimas +6 more
openaire +4 more sources
Resveratrol-induced brown fat-like phenotype in 3T3-L1 adipocytes partly via mTOR pathway
Background: Browning of white adipose tissues (WAT) is recognized as a novel way to combat obesity and its related comorbidities. Thus, a lot of dietary agents contributing to browning of WAT have been identified.
Zihui Liu +7 more
doaj +1 more source
Effect of Hyperoside on the Inhibition of Adipogenesis in 3t3-L1 Adipocytes [PDF]
The inhibition of adipocyte differentiation has a significant role on the prevention of obesity and obesity-associated complications.In this study, we aimed to detect whether hyperoside is able to inhibit the conversion of pre-adiposits into mature adiposits.3T3-L1 pre-adipocytes were stimulated so as to differentiate into mature adipocytes. Hyperoside
openaire +3 more sources
Background Capsaicinoids, such as dihydrocapsaicin (DHC), exert the health-promoting effects of chili peppers on energy metabolism. The metabolic responses to capsaicinoids are primarily mediated through transient receptor potential cation channel ...
Uthai Wichai +8 more
doaj +1 more source
Previous studies have demonstrated that cachectin/tumor necrosis factor (TNF) inhibits lipoprotein lipase (LPL) activity in cultures of 3T3-L1 cells.
P A Kern
doaj +1 more source

