Results 41 to 50 of about 43,182 (237)

Resveratrol-induced brown fat-like phenotype in 3T3-L1 adipocytes partly via mTOR pathway

Food & Nutrition Research, 2020
Background: Browning of white adipose tissues (WAT) is recognized as a novel way to combat obesity and its related comorbidities. Thus, a lot of dietary agents contributing to browning of WAT have been identified.
Zihui Liu, Weiyao Liao, Xiaohan Yin, Xinjie Zheng, Qingrong Li, Hongmin Zhang, Lin Zheng, Xiang Feng   +7 more
doaj   +1 more source

Cellular responses to 8-methyl nonanoic acid, a degradation by-product of dihydrocapsaicin, in 3T3-L1 adipocytes

BMC Complementary Medicine and Therapies, 2023
Background Capsaicinoids, such as dihydrocapsaicin (DHC), exert the health-promoting effects of chili peppers on energy metabolism. The metabolic responses to capsaicinoids are primarily mediated through transient receptor potential cation channel ...
Uthai Wichai, Ploychanok Keawsomnuk, Saowarose Thongin, Chaiyot Mukthung, Chatchai Boonthip, Pattama Pittayakhajonwut, Pimonrat Ketsawatsomkron, Nuntavan Bunyapraphatsara, Kenjiro Muta   +8 more
doaj   +1 more source

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. [PDF]

, 2016
Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity.
Bakirtzi, K, Cheng, M, Fisseha, E, Fleshner, P, Gallo, RL, Hing, TC, Ho, S, Hoang-Ngoc Tran, D, Hoang-Yen Tran, D, Karagiannides, I, Koon, HW, Law, I, Lee, EC, Lee, JE, Li, Z, Mattai, SA, McGovern, DPB, Ortiz, C, Robbins, L, Sallam, T, Shieh, C, Shih, DQ, Sideri, A, Su, B, Targan, SR, Vu, M   +25 more
core   +1 more source

Recombinant human tumor necrosis factor does not inhibit lipoprotein lipase in primary cultures of isolated human adipocytes

Journal of Lipid Research, 1988
Previous studies have demonstrated that cachectin/tumor necrosis factor (TNF) inhibits lipoprotein lipase (LPL) activity in cultures of 3T3-L1 cells.
P A Kern
doaj   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A, Lee, Rebecca A, Wang, Jen-Chywan   +2 more
core   +2 more sources

A dose-dependent effect of dimethyl sulfoxide on lipid content, cell viability and oxidative stress in 3T3-L1 adipocytes

Toxicology Reports, 2018
Dimethyl sulfoxide (DMSO) is an effective solvent and cytoprotectant agent that can induce diverse actions in experimental settings, ranging from metabolic stress to cytotoxic effects depending on the concentration used.
Phiwayinkosi V. Dludla, Babalwa Jack, Amsha Viraragavan, Carmen Pheiffer, Rabia Johnson, Johan Louw, Christo J.F. Muller   +6 more
doaj   +1 more source

The Mitogenic and Antiapoptotic Actions of Ghrelin in 3T3-L1 Adipocytes [PDF]

Molecular Endocrinology, 2004
Ghrelin, a stomach-derived hormone, induces adiposity when administered to rodents. Because ghrelin receptor is abundantly expressed in adipose tissue, we investigated the role of ghrelin in adipocyte biology. We observed ghrelin receptor expression in 3T3-L1 preadipocytes and adipocytes.
Min Seon, Kim, Cho Ya, Yoon, Pil Geum, Jang, Young Joo, Park, Chan Soo, Shin, Hye Sun, Park, Je Won, Ryu, Youngmi Kim, Pak, Joong Yeol, Park, Ki Up, Lee, Seong Yeon, Kim, Hong Kyu, Lee, Young Bum, Kim, Kyong Soo, Park   +13 more
openaire   +2 more sources

Alternate routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4 [PDF]

, 2015
Insulin-stimulated delivery of glucose transporters (GLUT4) from specialized intracellular GLUT4 storage vesicles (GSVs) to the surface of fat and muscle cells is central to whole-body glucose.
Bryant, Nia J., Gould, Gwyn W., Kioumourtzoglou, Dimitrios, Pryor, Paul R.   +3 more
core   +3 more sources

Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes [PDF]

Journal of Lipid Research, 2012
Lipoic acid (LA) is a naturally occurring compound with beneficial effects on obesity. The aim of this study was to evaluate its effects on lipolysis in 3T3-L1 adipocytes and the mechanisms involved. Our results revealed that LA induced a dose- and time-dependent lipolytic action, which was reversed by pretreatment with the c-Jun N-terminal kinase ...
Marta Fernández-Galilea, Patricia Pérez-Matute, Pedro L Prieto-Hontoria, J Alfredo Martinez, Maria J Moreno-Aliaga   +4 more
openaire   +3 more sources

IRS1/PI3K/AKT pathway signal involved in the regulation of glycolipid metabolic abnormalities by Mulberry (Morus alba L.) leaf extracts in 3T3-L1 adipocytes

Chinese Medicine, 2020
Background Mulberry (Morus alba L.) leaf tea benefits the control of diabetes in Asian nations. This study was aim to investigate if the flavonoids, which extracts from mulberry leaves, could regulate the metabolism of glycolipid, and to investigate if ...
Qinghai Meng, Xu Qi, Ying Chao, Qi Chen, Peng Cheng, Xichao Yu, Meiyu Kuai, Jingzhen Wu, Wenwen Li, Qichun Zhang, Yu Li, Huimin Bian   +11 more
doaj   +1 more source