Results 41 to 50 of about 259,851 (238)

A dose-dependent effect of dimethyl sulfoxide on lipid content, cell viability and oxidative stress in 3T3-L1 adipocytes

Toxicology Reports, 2018
Dimethyl sulfoxide (DMSO) is an effective solvent and cytoprotectant agent that can induce diverse actions in experimental settings, ranging from metabolic stress to cytotoxic effects depending on the concentration used.
Phiwayinkosi V. Dludla, Babalwa Jack, Amsha Viraragavan, Carmen Pheiffer, Rabia Johnson, Johan Louw, Christo J.F. Muller   +6 more
doaj   +1 more source

Cistanche tubulosa phenylethanoid glycosides suppressed adipogenesis in 3T3-L1 adipocytes and improved obesity and insulin resistance in high-fat diet induced obese mice

BMC Complementary Medicine and Therapies, 2022
Background Cistanche tubulosa is an editable and medicinal traditional Chinese herb and phenylethanoid glycosides are its major components, which have shown various beneficial effects such as anti-tumor, anti-oxidant and neuroprotective activities ...
Dilinazi Abudujilile, Weilan Wang, Alimu Aimaier, Lili Chang, Yuliang Dong, Yiye Wang, Xu Fan, Yu Ma, Yongli Wang, Dilinigeer Ziyayiding, Yuan Ma, Jie Lv, Jinyao Li   +12 more
doaj   +1 more source

The Mitogenic and Antiapoptotic Actions of Ghrelin in 3T3-L1 Adipocytes [PDF]

Molecular Endocrinology, 2004
Ghrelin, a stomach-derived hormone, induces adiposity when administered to rodents. Because ghrelin receptor is abundantly expressed in adipose tissue, we investigated the role of ghrelin in adipocyte biology. We observed ghrelin receptor expression in 3T3-L1 preadipocytes and adipocytes.
Min Seon, Kim, Cho Ya, Yoon, Pil Geum, Jang, Young Joo, Park, Chan Soo, Shin, Hye Sun, Park, Je Won, Ryu, Youngmi Kim, Pak, Joong Yeol, Park, Ki Up, Lee, Seong Yeon, Kim, Hong Kyu, Lee, Young Bum, Kim, Kyong Soo, Park   +13 more
openaire   +2 more sources

Adipocyte-Related Genes and Transcription Factors were affected by Ganoderma lucidum during 3T3-L1 Differentiation

Journal of Pharmacopuncture, 2009
In this study, the effects of Ganoderma lucidum (GL) on fat metabolism were performed in 3T3-L1 adipocytes. The effects of GL on 3T3-L1 preadipocytes differentiation were also examined. Our results showed that GL decreased the TG content by ORO staining.
Chae-Woo Lee, Hyun-Min Yoon, Kyung-Hwa Kang   +2 more
doaj   +1 more source

Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells

Toxicology Reports, 2018
The objective of this study was to evaluate the anti-obesity activity and the action mechanism of Cissus quadrangularis extracts (CQR-300) in 3T3-L1 adipocytes. Cissus quadrangularis was extracted with hot water, resulting in CQR-300.
Hae Jin Lee, Bao Le, Dong-Ryung Lee, Bong-Keun Choi, Seung Hwan Yang   +4 more
doaj   +1 more source

IRS1/PI3K/AKT pathway signal involved in the regulation of glycolipid metabolic abnormalities by Mulberry (Morus alba L.) leaf extracts in 3T3-L1 adipocytes

Chinese Medicine, 2020
Background Mulberry (Morus alba L.) leaf tea benefits the control of diabetes in Asian nations. This study was aim to investigate if the flavonoids, which extracts from mulberry leaves, could regulate the metabolism of glycolipid, and to investigate if ...
Qinghai Meng, Xu Qi, Ying Chao, Qi Chen, Peng Cheng, Xichao Yu, Meiyu Kuai, Jingzhen Wu, Wenwen Li, Qichun Zhang, Yu Li, Huimin Bian   +11 more
doaj   +1 more source

Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes [PDF]

Journal of Lipid Research, 2012
Lipoic acid (LA) is a naturally occurring compound with beneficial effects on obesity. The aim of this study was to evaluate its effects on lipolysis in 3T3-L1 adipocytes and the mechanisms involved. Our results revealed that LA induced a dose- and time-dependent lipolytic action, which was reversed by pretreatment with the c-Jun N-terminal kinase ...
Marta Fernández-Galilea, Patricia Pérez-Matute, Pedro L Prieto-Hontoria, J Alfredo Martinez, Maria J Moreno-Aliaga   +4 more
openaire   +3 more sources

HDL stimulates glucose uptake in 3T3-L1 adipocytes.

, 2013
3T3-L1 adipocytes were incubated with vehicle or stimulators for 30 min before being incubated for another 30 min with 1-[3H]-2- deoxyglucose. (A) 3T3-L1 adipocytes were incubated with vehicle (BSA), HDL (50 µg protein/ml), insulin (100 nmol/L) or ...
Lina Wang (44695), Lai Jin (345813), Cheng Chen (136164), Shengnan Li (345816), Yun Zhang (131894), Qichun Zhang (345810), Rui Guo (134395), Rong Wan (184712), Haihua Feng (198813)   +8 more
core   +1 more source

Layer‐Specific Dermal and Subcutaneous Delivery via Modular LNP–Hydrogel‐Integrated Threaded Microneedles

Advanced Science, EarlyView.
Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie, Yixiang Zhang, Shifeng Ling, Yuxuan Huang, Yingying Wei, Rao Fu, Jiahao He, Baikun Liu, Lucia Zhou, Kaifeng Huo, Yida Wang, Qingfeng Li, Yawei Du, Wenguo Cui, Yun Xie   +14 more
wiley   +1 more source

Effects of Chrysoeriol on Adipogenesis and Lipolysis in 3T3-L1 Adipocytes

Foods, 2022
We examined the effect of chrysoeriol on adipogenesis and lipolysis and elucidated the underlying molecular mechanisms. Chrysoeriol inhibited fat deposition in adipocytes. Treatment with chrysoeriol suppressed the expression of peroxisome proliferator-activated receptor γ, fatty acid synthase, fatty acid-binding protein, CCAAT/enhancer-binding proteins
Jinhee Song, Hana Lee, Huijin Heo, Junsoo Lee, Younghwa Kim   +4 more
openaire   +3 more sources