Results 61 to 70 of about 259,851 (238)
Frontiers in Pharmacology, 2021 Background: The prevalence of non-alcoholic fatty liver disease (NAFLD) keeps growing recently.Purpose: To investigate the effects and mechanisms of naringenin (NAR) on NAFLD.Methods: High-fat diet (HFD)-induced NAFLD rats were orally administered with ...
Ying Yang +11 more
doaj +1 more source
Irisin regulates thermogenesis and lipolysis in 3T3-L1 adipocytes
Biochimica et Biophysica Acta (BBA) - General Subjects, 2022 Adipose tissue plays a pivotal role in the development and progression of the metabolic syndrome which along with its complications is an epidemic of the 21st century. Irisin is an adipo-myokine secreted mainly by skeletal muscle and targeting, among others, adipose tissue.
Vliora M. +7 more
openaire +2 more sources
BMC Research Notes, 2022 Objective The mesoderm-specific transcript (Mest) is an imprinted gene that is transcribed from the paternal allele. It is a marker of adipose tissue expansion; however, it is uncertain whether Mest expression promotes or suppresses adipogenic ...
Yoshito Kadota +3 more
doaj +1 more source
Regulated renin release from 3T3-L1 adipocytes [PDF]
American Journal of Physiology-Endocrinology and Metabolism, 2009 Whereas adipose tissue possesses a local renin-angiotensin system, the synthesis and regulated release of renin has not been addressed. To that end, we utilized differentiating 3T3-L1 cells and analyzed renin expression and secretion. Renin mRNA expression and protein enzymatic activity were not detectable in preadipocytes.
Jason D, Fowler +6 more
openaire +2 more sources
, 2013 CAR-3T3-L1 preadipocytes and adipocytes were infected with adenovirus expressing Ephrin-B1 (Ad-EfnB1) or β-galactosidase (Ad-βgal). CAR-3T3-L1 adipocytes were transfected with Ad-EfnB1 or Ad-βgal on day 7 after differentiation and cocultured with RAW264 ...
Yu Tsushima (465409) +11 more
core +1 more source
JSFA reports, EarlyView.Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed +5 more
wiley +1 more source
The Extract of Humulus japonicus Inhibits Lipogenesis and Promotes Lipolysis via PKA/p38 Signaling
Obesity FactsIntroduction: Previous research has shown that an aqueous extract of Humulus japonicus (EH) can ameliorate hypertension, nonalcoholic fatty liver disease, and oxidative stress in adipocytes by activating the thermogenic pathway.
Jaw Long Sun +7 more
doaj +1 more source
Brd2 inhibits adipogenesis via the ERK1/2 signaling pathway in 3T3-L1 adipocytes.
PLoS ONE, 2013 Bromodomain-containing protein 2 (Brd2) is a nuclear serine/threonine kinase involved in transcriptional regulation. In 3T3-L1 adipocytes, Brd2 normally co-represses PPARγ (peroxisome proliferator-activated receptor gamma) and inhibits adipogenesis. Here,
Kun Zang +9 more
doaj +1 more source
Biology, 2022 β3-adrenergic receptor (β3-AR) is expressed predominantly in mature white and brown/beige adipocytes. Although the lipolytic and thermogenic role of β3-AR in brown/beige adipocytes is well defined, the adipogenic role of β3-AR in white adipocytes remains
Amir Roshanzadeh +4 more
doaj +1 more source
Effects of CAde on 3T3-L1 pre-adipocytes cell viability.
, 2018 Effects of CAde on 3T3-L1 pre-adipocytes cell viability.
Michele Campitelli (4921576) +12 more
core +1 more source