Results 81 to 90 of about 259,851 (238)

Dietary Flavonoid Hyperoside Ameliorates High‐Fat Diet‐Induced Type 2 Diabetes Mellitus by Enhancing Brown Adipose Tissue Thermogenesis, White Adipose Tissue Browning, and Gut Microbiota Remodeling

Phytotherapy Research, EarlyView.
Hyperoside ameliorates metabolic dysfunction in high‐fat diet‐induced type 2 diabetic mice, accompanied by enhanced brown adipose tissue thermogenic activity, inguinal white adipose tissue browning‐related changes, reduced M1 macrophage polarization, and gut microbiota remodeling.
WeiFeng Cai, WenXin Zeng, Yu Luo, Qiang Liu, CuiPing Jiang, YanKui Yi, JieYu Chen, ChunYan Shen   +7 more
wiley   +1 more source

Timeline for ¹³C-tracer experiments with 3T3-L1 adipocytes.

, 2016
Timeline for 13C-tracer experiments with 3T3-L1 adipocytes.
Nicholas Marze (841739), Scott B. Crown (841738), Maciek R. Antoniewicz (841740)   +2 more
core   +1 more source

Cinnamic Acid Attenuates Ethanol‐Exacerbated Hepatocyte Pyroptosis in Type 2 Diabetes via AMPK‐Mediated NLRP3/GSDMD Inhibition

Phytotherapy Research, EarlyView.
CA directly binds to and activates AMPK to suppress NLRP3/GSDMD signaling, thereby alleviating hepatocyte pyroptosis in T2DM mice. ABSTRACT Type 2 diabetes mellitus (T2DM) is frequently accompanied by chronic ethanol (ET) consumption, which worsens metabolic dysregulation and organ damage.
Huaiying Tang, Qin Xiang, Yue Zhang, Yu Zhang, Xiangxiang Fu, Liming Tan, Yongli Zhang, Siqi Li, Dong Gong, Xu Guo, Yonghong Zhang, Li Chen, Tao Zheng, Qibin Wang   +13 more
wiley   +1 more source

Regulation of Oip5 in 3T3-L1 adipocytes.

, 2014
A, Change of Oip5 mRNA level during 3T3-L1 adipocytes differentiation ...
Yu Tsushima (465409), Yoshihiro Ogawa (15560), Norikazu Maeda (126238), Iichiro Shimomura (126258), Ryohei Sekimoto (465408), Keisuke Matsuda (465410), Masaya Yamaoka (126236), Takuya Mori (445318), Hitoshi Nishizawa (465411), Kana Inoue (465407), Tohru Funahashi (126255), Takayoshi Suganami (219173)   +11 more
core   +1 more source

Magnoflorine Ameliorates MASH in Mice Fed a High‐Fat and High‐Fructose Diet by Promoting AMPK‐Mediated Lipophagy and Fatty Acid Oxidation

Phytotherapy Research, EarlyView.
Magnoflorine ameliorates metabolic dysfunction‐associated steatohepatitis by promoting AMPKα‐mediated lipophagy and fatty acid oxidation. ABSTRACT Emerging as a significant clinical burden, metabolic dysfunction‐associated steatohepatitis (MASH) continues to challenge global healthcare systems due to limited effective interventions.
Zhengjie Lu, Tongyun Mao, Longxin Chai, Kaiqi Chen, Kexin Liu, Cong Zhang, Hao Kou   +6 more
wiley   +1 more source

Qualitative and quantitative analysis of lipid droplets in mature 3T3-L1 adipocytes using oil red O

STAR Protocols
Summary: By differentiating into mature adipocytes, 3T3-L1 cells can be utilized as a model cell line to investigate (pre)adipocyte function in vitro. Here, we present a protocol for combining qualitative and quantitative analysis of lipid droplets in ...
Isabell Kaczmarek, Tomáš Suchý, Martina Strnadová, Doreen Thor   +3 more
doaj   +1 more source

Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells. [PDF]

PLoS ONE, 2018
Metabolic and/or endocrine dysfunction of the white adipose tissue (WAT) contribute to the development of metabolic disorders, such as Type 2 Diabetes (T2D).
Gregory Alexander Raciti, Francesca Fiory, Michele Campitelli, Antonella Desiderio, Rosa Spinelli, Michele Longo, Cecilia Nigro, Giacomo Pepe, Eduardo Sommella, Pietro Campiglia, Pietro Formisano, Francesco Beguinot, Claudia Miele   +12 more
doaj   +1 more source

Characteristics of 3T3-L1 cells with overexpressed Brd2.

, 2013
3T3-L1 cells transfected with pmBrd2 and control (pcDNA3.1), respectively. (A) Adipogenic differentiation of 3T3-L1 adipocytes from pre-adipocytes and Oil Red O staining on day 4 of treatment reveals lipids in cells that have undergone differentiation ...
Jingyu Wang (292122), Min Yu (120607), Miaofang Dong (475610), Fangnian Wang (475613), Xiaoxia Liu (294088), Kun Zang (475609), Yuxiong Wang (152709), Yimin Li (475612), Ruixin Sun (475611), Yinong Huang (312166)   +9 more
core   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Activation of AMP-Activated Protein Kinase Attenuates Tumor Necrosis Factor-α-Induced Lipolysis via Protection of Perilipin in 3T3-L1 Adipocytes [PDF]

Endocrinology and Metabolism, 2014
BackgroundTumor necrosis factor (TNF)-α and AMP-activated protein kinase (AMPK) are known to stimulate and repress lipolysis in adipocytes, respectively; however, the mechanisms regulating these processes have not been completely elucidated.MethodsThe ...
Seok-Woo Hong, Jinmi Lee, Se Eun Park, Eun-Jung Rhee, Cheol-Young Park, Ki-Won Oh, Sung-Woo Park, Won-Young Lee   +7 more
doaj   +1 more source