Results 71 to 80 of about 259,851 (238)

Anti‐hypercholesterolemic effects of barley and its role in the management of metabolic disorders: A comprehensive review

JSFA reports, EarlyView.
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Sagun Kharel, Umrah Zafar, Naima Tariq, Muhammad Maaz, Mutjardah Zarrish, Nuzhat Shamim, Bipindra Pandey   +8 more
wiley   +1 more source

Thyroid-stimulating hormone inhibits adipose triglyceride lipase in 3T3-L1 adipocytes through the PKA pathway. [PDF]

PLoS ONE, 2015
Thyroid-stimulating hormone (TSH) has been shown to play an important role in the regulation of triglyceride (TG) metabolism in adipose tissue. Adipose triglyceride lipase (ATGL) is a rate-limiting enzyme controlling the hydrolysis of TG. Thus far, it is
Dongqing Jiang, Shizhan Ma, Fei Jing, Chao Xu, Fang Yan, Aihong Wang, Jiajun Zhao   +6 more
doaj   +1 more source

Impact of stress hormone on adipogenesis in the 3T3-L1 adipocytes [PDF]

Cytotechnology, 2013
Stress hormone is known to play a vital role in lipolysis and adipogenesis in fat cells. The present study was carried out to evaluate the effect of epinephrine on adipogenesis in the 3T3-L1 cells. The investigation on adipogenesis was done in both mono and co-cultured 3T3-L1 cells.
Muthuraman, Pandurangan, Sambandam, Ravikumar   +1 more
openaire   +2 more sources

Adipolytic and adipogenic activities of SUB885C in 3T3-L1 adipocytes.

, 2012
(A) Glycerol release as the result of adipolysis in 3T3-L1 adipocytes after incubation with SUB885C (500× and 2500× diluted) and 20 µM isoproterenol dissolved in DMSO with 1% as final concentration. (B) Inhibition of adipose conversion in differentiating
Heng Wei (138563), Guowang Xu (135666), Louis M. Havekes (123558), Suzan Wopereis (186741), Theo H. Reijmers (135649), Thomas Hankemeier (135670), Renger F. Witkamp (186759), Elwin R. Verheij (186763), Jildau Bouwman (186744), Chunxiu Hu (186733), Raymond Ramaker (186747), Anita M. van den Hoek (186737), Henrie A. A. J. Korthout (186750), Marco Vennik (186753), Jan van der Greef (39107), Mei Wang (130842)   +15 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Centipede grass exerts anti-adipogenic activity through inhibition of C/EBPβ, C/EBPα, and PPARγ expression and the AKT signaling pathway in 3T3-L1 adipocytes

BMC Complementary and Alternative Medicine, 2012
Background Centipede grass (CG) originates from China and South America and is reported to contain several C-glycosyl flavones and phenolic constituents, including maysin and luteolin derivatives.
Park Hyoung Joon, Chung Byung Yeoup, Lee Min-Kwon, Song Yuno, Lee Seung Sik, Chu Gyo Moon, Kang Suk-Nam, Song Young Min, Kim Gon-Sup, Cho Jae-Hyeon   +9 more
doaj   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

Phytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li, Yang‐Chi‐Dung Lin, Hsi‐Yuan Huang, Jihang Chen, Huali Zuo, Yun Tang, Hsien‐Da Huang   +6 more
wiley   +1 more source

TG-interacting factor is required for the differentiation of preadipocytes

Journal of Lipid Research, 2008
The accumulation of visceral adipose tissue is closely associated with insulin resistance and metabolic syndrome. Therefore, it is important to identify genes that are required for adipocyte differentiation.
Takahiro Horie, Koh Ono, Minako Kinoshita, Hitoo Nishi, Kazuya Nagao, Teruhisa Kawamura, Yukiko Abe, Hiromichi Wada, Akira Shimatsu, Toru Kita, Koji Hasegawa   +10 more
doaj   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Regulation of Ephrin-B1 in 3T3-L1 adipocytes.

, 2013
A, Changes in Ephrin-B1 mRNA level during differentiation of 3T3-L1 adipocytes. B, Effect of tumor necrosis factor-α (TNF-α) on Ephrin-B1 mRNA level in 3T3-L1 adipocytes.
Yu Tsushima (465409), Yoshihiro Ogawa (15560), Norikazu Maeda (126238), Iichiro Shimomura (126258), Ryohei Sekimoto (465408), Keisuke Matsuda (465410), Masaya Yamaoka (126236), Takuya Mori (445318), Hitoshi Nishizawa (465411), Kana Inoue (465407), Tohru Funahashi (126255), Takayoshi Suganami (219173)   +11 more
core   +1 more source