Results 51 to 60 of about 259,851 (238)

Immunostainings of CAR-3T3-L1 adipocytes overexpressing Oip5.

, 2014
A, Images of EdU staining in the adenovirus-transfected Coxsackie-Adenovirus Receptor (CAR)-3T3-L1 adipocytes. CAR-3T3-L1 adipocytes were stained with 5-ethynyl-2′-deoxyuridine (EdU) and 4′,6-diamidino-2-phenylindole (DAPI) and analyzed by HS All-in-one ...
Yu Tsushima (465409), Yoshihiro Ogawa (15560), Norikazu Maeda (126238), Iichiro Shimomura (126258), Ryohei Sekimoto (465408), Keisuke Matsuda (465410), Masaya Yamaoka (126236), Takuya Mori (445318), Hitoshi Nishizawa (465411), Kana Inoue (465407), Tohru Funahashi (126255), Takayoshi Suganami (219173)   +11 more
core   +1 more source

A Bi‐Adjuvant Senolytic Nanovaccine Modulating Dendritic Cell Senescence Ameliorates Aging‐Related Metabolic Dysfunction

Advanced Science, EarlyView.
An active biomaterial‐based bi‐adjuvant nanovaccine restores the immunocompetence of aged dendritic cells to overcome senescent cell tolerance. Accompanied by the downregulation of mitotic kinases Aurka/b and attenuation of senescence‐associated PI3K/AKT phosphorylation, the nanovaccine enhances antigen‐presenting capacity and promotes potent cytotoxic
Qingxu Song, Xiaoxue Du, Wenbo Dong, Ying Wang, Xiaojing Wang, Qiliang Yin   +5 more
wiley   +1 more source

Acacetin from Traditionally Used Saussurea involucrata Kar. et Kir. Suppressed Adipogenesis in 3T3-L1 Adipocytes and Attenuated Lipid Accumulation in Obese Mice

Frontiers in Pharmacology, 2017
Acacetin, a flavone that can be isolated from the Saussurea involucrata plant, has anti-tumor and anti-inflammatory properties that ameliorate airway hyperresponsiveness in asthmatic mice.
Chian-Jiun Liou, Chian-Jiun Liou, Shu-Ju Wu, Shu-Ju Wu, Li-Chen Chen, Kuo-Wei Yeh, Chih-Ying Chen, Wen-Chung Huang, Wen-Chung Huang   +8 more
doaj   +1 more source

DNA Methylation Suppresses Leptin Gene in 3T3-L1 Adipocytes. [PDF]

PLoS ONE, 2016
Leptin is a key regulator of energy intake and expenditure. This peptide hormone is expressed in mouse white adipose tissue, but hardly expressed in 3T3-L1 adipocytes.
Masashi Kuroda, Ayako Tominaga, Kasumi Nakagawa, Misa Nishiguchi, Mayu Sebe, Yumiko Miyatake, Tadahiro Kitamura, Rie Tsutsumi, Nagakatsu Harada, Yutaka Nakaya, Hiroshi Sakaue   +10 more
doaj   +1 more source

Effects of leukemia inhibitory factor on 3T3-L1 adipocytes [PDF]

Journal of Endocrinology, 2005
Abstract Leukemia inhibitory factor (LIF) is a member of the gp130 cytokine family and signals through the receptor complex of gp130 and the LIF receptor (LIFR) to activate the JAK/STAT signaling cascade. Since LIF activates STATs 1 and 3 in adipocytes, we examined the effects of LIF on 3T3-L1 adipocytes.
Jessica C, Hogan, Jacqueline M, Stephens
openaire   +2 more sources

Knockdown of biglycan in 3T3-L1 adipocytes.

, 2013
A) Biglycan expression from 3T3-L1 mature adipocytes treated with siRNA against biglycan (“si biglycan”) or nontargeting siRNA (“scrambled”). Results are from RT-PCR and western blot for core biglycan protein (representative blot).
Meliza G. Ward (297567), Kolapo M. Ajuwon (297569)   +1 more
core   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Inhibition of Adipogenesis by Diphlorethohydroxycarmalol (DPHC) through AMPK Activation in Adipocytes

Marine Drugs, 2019
The purpose of this study was to investigate the antiobesity effect and the mechanism of action of diphlorethohydroxycarmalol (DPHC) isolated from Ishige okamurae in 3T3-L1 cells.
Min-Cheol Kang, Yuling Ding, Hyun-Soo Kim, You-Jin Jeon, Seung-Hong Lee   +4 more
doaj   +1 more source

Evidence of mature adipocyte proliferation regulated by proliferin [PDF]

, 2010
Despite much research, whether mature adipocytes proliferate remains controversial. Here, we examined 5-bromo-2′-deoxyuridine (BrdU)-labelling of mature adipocytes.
Kazuo Kajita, Hiroyuki Morita, Yuzo Takahashi, Yoshihiro Uno, Tatsuo Ishizuka, Aki Minami, Takahide Ikeda, Hideyuki Okada, Kei Fujioka, Masahiro Yamauchi, Toshiko Kajita, Isao Nagano, Wu Zhiliang, Mitsuru Seishima, Ichiro Mori, Takayuki Hanamoto, Masao Takemura   +16 more
core  

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source