Results 51 to 60 of about 43,182 (237)

Cistanche tubulosa phenylethanoid glycosides suppressed adipogenesis in 3T3-L1 adipocytes and improved obesity and insulin resistance in high-fat diet induced obese mice

BMC Complementary Medicine and Therapies, 2022
Background Cistanche tubulosa is an editable and medicinal traditional Chinese herb and phenylethanoid glycosides are its major components, which have shown various beneficial effects such as anti-tumor, anti-oxidant and neuroprotective activities ...
Dilinazi Abudujilile, Weilan Wang, Alimu Aimaier, Lili Chang, Yuliang Dong, Yiye Wang, Xu Fan, Yu Ma, Yongli Wang, Dilinigeer Ziyayiding, Yuan Ma, Jie Lv, Jinyao Li   +12 more
doaj   +1 more source

Adipocyte-Related Genes and Transcription Factors were affected by Ganoderma lucidum during 3T3-L1 Differentiation

Journal of Pharmacopuncture, 2009
In this study, the effects of Ganoderma lucidum (GL) on fat metabolism were performed in 3T3-L1 adipocytes. The effects of GL on 3T3-L1 preadipocytes differentiation were also examined. Our results showed that GL decreased the TG content by ORO staining.
Chae-Woo Lee, Hyun-Min Yoon, Kyung-Hwa Kang   +2 more
doaj   +1 more source

Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]

, 1994
The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Altan, Aoki, Avruch, Bak, Begum, Brown, Caren, Clancy, Cooper, Cushman, Daniels, Davidson, Farese, Feldman, Feldman, Gavin, Geisen, Gould, Guinovart, Hirshman, Honnor, Jacobs, Jacobs, Jacobs, James, James, Karnieli, Kirsch, Klip, Kolterman, Kono, Lane, Larner, Lawrence, Lawson, Lebovitz, Leichter, Maloff, Mandarino, Misek, Moody, Müller, Müller, Müller, Müller, Müller, Okuno, Oron, Osegawa, Panten, Popov, Putnam, Reusch, Rogers, Roskoski, Saltiel, Saltiel, Saltiel, Simonson, Smith, Solomon, Standing, Suissa, Suzuki, Tordjman, Towbin, Van Putten, Vila, Villalba, Wang, Wang, Wieland, Wray, Yalow, Zinman, Zuber   +75 more
core   +1 more source

Effects of leukemia inhibitory factor on 3T3-L1 adipocytes [PDF]

Journal of Endocrinology, 2005
Leukemia inhibitory factor (LIF) is a member of the gp130 cytokine family and signals through the receptor complex of gp130 and the LIF receptor (LIFR) to activate the JAK/STAT signaling cascade. Since LIF activates STATs 1 and 3 in adipocytes, we examined the effects of LIF on 3T3-L1 adipocytes.
Jessica C, Hogan, Jacqueline M, Stephens
openaire   +2 more sources

Effects of Chrysoeriol on Adipogenesis and Lipolysis in 3T3-L1 Adipocytes

Foods, 2022
We examined the effect of chrysoeriol on adipogenesis and lipolysis and elucidated the underlying molecular mechanisms. Chrysoeriol inhibited fat deposition in adipocytes. Treatment with chrysoeriol suppressed the expression of peroxisome proliferator-activated receptor γ, fatty acid synthase, fatty acid-binding protein, CCAAT/enhancer-binding proteins
Jinhee Song, Hana Lee, Huijin Heo, Junsoo Lee, Younghwa Kim   +4 more
openaire   +3 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells

Toxicology Reports, 2018
The objective of this study was to evaluate the anti-obesity activity and the action mechanism of Cissus quadrangularis extracts (CQR-300) in 3T3-L1 adipocytes. Cissus quadrangularis was extracted with hot water, resulting in CQR-300.
Hae Jin Lee, Bao Le, Dong-Ryung Lee, Bong-Keun Choi, Seung Hwan Yang   +4 more
doaj   +1 more source

DNA Methylation Suppresses Leptin Gene in 3T3-L1 Adipocytes. [PDF]

PLoS ONE, 2016
Leptin is a key regulator of energy intake and expenditure. This peptide hormone is expressed in mouse white adipose tissue, but hardly expressed in 3T3-L1 adipocytes.
Masashi Kuroda, Ayako Tominaga, Kasumi Nakagawa, Misa Nishiguchi, Mayu Sebe, Yumiko Miyatake, Tadahiro Kitamura, Rie Tsutsumi, Nagakatsu Harada, Yutaka Nakaya, Hiroshi Sakaue   +10 more
doaj   +1 more source

Sclerostin Enhances Adipocyte Differentiation in 3T3‐L1 Cells [PDF]

Journal of Cellular Biochemistry, 2016
ABSTRACTSclerostin, a secreted protein encoded by the Sost gene, is produced by osteocytes and is inhibited by osteoblast differentiation and bone formation. Recently, a functional association between bone and fat tissue has been suggested, and a correlation between circulating sclerostin levels and lipid metabolism has been reported in humans. However,
Ukita, Mayumi, Yamaguchi, Taihiko, Ohata, Noboru, Tamura, Masato   +3 more
openaire   +3 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source