Results 121 to 130 of about 4,897,037 (304)

SensEnhance: A Genetic Circuit for Converting Endogenous Mammalian Gene Signals Into High‐Dynamic‐Range Genetic Readouts

open access: yesAdvanced Science, EarlyView.
Here, we present SensEnhance, a modular genetic circuit that converts leaky, low‐dynamic‐range promoter signals into tightly controlled, high‐dynamic‐range outputs. Applied to mechanosensing and IL‐6‐responsive promoters, SensEnhance increases fold changes from 2.6‐ and 2.5‐fold in promoter‐only configurations to over 20‐ and 14‐fold, respectively ...
Miguel Baños   +4 more
wiley   +1 more source

Growth and Drug Interaction Monitoring of NIH 3T3 Cells by Image Analysis and Capacitive Biosensor. [PDF]

open access: yesMicromachines (Basel), 2021
Lee G   +7 more
europepmc   +1 more source

Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance

open access: yesAdvanced Intelligent Discovery, EarlyView.
Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen   +4 more
wiley   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

open access: yesAdvanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang   +12 more
wiley   +1 more source

Differential growth factor expression in transformed mouse NIH‐3T3 cells

open access: yes, 1990
The expression of growth factor‐specific mRNA transcripts and the presence of biologically active growth factors in the conditioned medium and in the cell extracts from mouse NIH‐3T3 cells transformed by different oncogences (Ki‐ras, mos, src, fms, fes ...
COLUCCI D'AMATO, Generoso Luca   +5 more
core   +1 more source

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

open access: yesAnimal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang   +9 more
wiley   +1 more source

Presence of xenogenic mouse RNA in RPE and IPE cells cultured on mitotically inhibited 3T3 fibroblasts

open access: yes, 2011
Mitotically inhibited 3T3 fibroblasts are used as feeder layers to culture a variety of cells. However, transplantation of human cells cultured on mitotically arrested mouse cells poses potential risks, such as disease transfer and contamination with 3T3
Peter Walter   +12 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

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