Results 51 to 60 of about 2,273 (170)

Transcriptomic analysis of wheat reveals possible resistance mechanism mediated by Yr10 to stripe rust

open access: yesStress Biology, 2023
Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a catastrophic disease that threatens global wheat yield. Yr10 is a race-specific all-stage disease resistance gene in wheat.
Zhongyi Wu   +8 more
doaj   +1 more source

A century of vitamin E research: The innovative journey from basic biology to synthetic bio‐manufacturing

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 4, Page 985-1012, April 2026.
For a century, Vitamin E has been studied for its health benefits. This review traces its journey from basic biological discovery, and the recent identification of its link to chlorophyll degradation, to the modern era of sustainable microbial manufacturing, highlighting the innovative technologies that define its future production.
Ruiqi Zhang   +7 more
wiley   +1 more source

Disruption of hmgA by DNA Duplication is Responsible for Hyperpigmentation in a Vibrio anguillarum Strain

open access: yesScientific Reports, 2019
Vibrio anguillarum 531A, isolated from a diseased fish in the Atlantic Ocean, is a mixture composed of about 95 and 5% of highly pigmented cells (strain 531Ad) and cells with normal levels of pigmentation (strain 531Ac), respectively.
Veronica Batallones   +18 more
doaj   +1 more source

A Chemical Probe for Increasing Leaf Tocopherol Levels by Coordinated Modulation of Biosynthesis, Competition and Storage

open access: yesPlant Biotechnology Journal, Volume 24, Issue 4, Page 2204-2219, April 2026.
ABSTRACT Plant biofortification with phytonutrients typically relies on metabolic engineering strategies known as ‘push’ (enhancing biosynthetic flux), ‘block’ (inhibiting competing pathways) and ‘pull’ (promoting metabolite storage). Here, we describe a novel synthetic compound, X57, that simultaneously targets biosynthesis, competition and storage to
Pablo Perez‐Colao   +4 more
wiley   +1 more source

Reinforcement learning-based generative artificial intelligence for novel pesticide design

open access: yesJournal of Advanced Research
Introduction: Pesticides play a pivotal role in ensuring food security, and the development of green pesticides is an inevitable trend in global agricultural progress. Although deep learning-based generative models have revolutionized de novo drug design
Ruoqi Yang   +6 more
doaj   +1 more source

Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.

open access: yesPLoS Biology, 2021
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations.
Marcos Sterkel   +17 more
doaj   +1 more source

Metaproteome Analysis of Short‐Term Thermal Stress in Three Sympatric Coral Species Reveals Divergent Host Responses

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
Short‐term thermal stress triggers distinct molecular responses in three sympatric coral species with contrasting thermal resilience. Proteomic and metabolomic profiling reveal both species‐specific and limited shared pathways underlying these stress responses.
Shrinivas Nandi   +5 more
wiley   +1 more source

Projected Warming of the Southern Ocean Disrupts Embryonic Development and Hatch Timing in Antarctic Fish

open access: yesGlobal Change Biology Communications, Volume 1, Issue 1, March 2026.
Embryos are particularly sensitive to thermal challenge. Antarctic fish embryos raised at projected Southern Ocean temperatures hatch during the winter, have a high incidence of morphological abnormalities, have shorter body lengths, and express genes indicative of cellular stress.
Margaret Streeter   +6 more
wiley   +1 more source

Role of the N-terminus in human 4-hydroxyphenylpyruvate dioxygenase activity

open access: yesThe Journal of Biochemistry, 2019
Abstract4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a key enzyme in tyrosine catabolism, catalysing the oxidation of 4-hydroxyphenylpyruvate to homogentisate. Genetic deficiency of this enzyme causes type III tyrosinaemia. The enzyme comprises two barrel-shaped domains formed by the N- and C-termini, with the active site located in the C-terminus ...
An-Ning, Feng   +5 more
openaire   +2 more sources

Optimizing the thermostability of triketone dioxygenase for engineering tolerance to mesotrione herbicide in soybean and cotton

open access: yesFrontiers in Plant Science
Optimized triketone dioxygenase (TDO) variants with enhanced temperature stability parameters were engineered to enable robust triketone tolerance in transgenic cotton and soybean crops.
Stephen M. G. Duff   +10 more
doaj   +1 more source

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