Results 101 to 110 of about 29,456 (286)

The synthesis of potential analgesics derived from thebaine [PDF]

open access: yes, 1979
The thesis describes the synthesis of novel bridged thebaine derivatives with heterocyclic rings attached to C-7 and a study of the associated chemistry. Use has been made of the α-hydrazide (3) formed from the α-ester (2), itself prepared by Diels-Alder
Michael Burton (4178776)
core  

Design, Synthesis and Anti Tubercular Screening of Triazolyl Pyrazoles as Possible MTB–CYP51 Inhibitors [PDF]

open access: yes, 2021
The present work was focused on the design, docking, synthesis, and evaluation of the antitubercular activity of triazole-linked pyrazole derivatives as possible CYP-51 (sterol 14α-demethylase) inhibitors.
Indumathi, L
core  

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

open access: yesAdvanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen   +7 more
wiley   +1 more source

Multi‐Crystal X‐Ray Diffraction (MCXRD) Bridges the Crystallographic Characterisation Gap in Chemistry and Materials Science: Application to MOFs

open access: yesAngewandte Chemie, EarlyView.
Multi‐crystal X‐ray diffraction (MCXRD) methods allow accurate structural characterisation with crystals too small for single‐crystal X‐ray diffraction and too large for electron diffraction, as demonstrated here for metal‐organic frameworks, and alleviate the radiation‐induced chemical changes that can result from using high‐intensity X‐ray sources to
Joshua P. Smith   +9 more
wiley   +2 more sources

Actoprotective properties of 7'-((3-thio-4-methyl-4H-1,2,4-triazole-5-yl)methyl)theophylline derivatives

open access: yesZaporožskij Medicinskij Žurnal, 2016
The aim of this work was the study of actoprotective activity of compounds, which combine sintons of 1,2,4-triazole-3-thiol and theophylline. Materials and methods.
A. S. Gotsulya
doaj  

The search of new biologically active compounds with antibacterial and antifungal activity among 1,2,4-triazole-3-thiol derivatives with the remnants of thiophene

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
The resistance of microorganisms to antimicrobial and antifungal drugs is still an actual issue in the modern world. Therefore, one of the possible ways to solve this problem is the creation of new drugs.
V. O. Salionov   +3 more
doaj   +1 more source

NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 41) [PDF]

open access: yes
s are provided for 131 patents and patent applications entered into the NASA scientific and technical information system during the period Jan. 1992 through Jun. 1992.

core   +1 more source

Expanding the Chemical Space of Cyclic Polyphthalaldehyde via Post‐Functionalization

open access: yesAdvanced Science, EarlyView.
In this work, we developed a post‐functionalization approach to achieve water‐soluble cyclic polyphthalaldehyde (cPPA) polymers via click chemistry. ABSTRACT Cyclic polyphthalaldehydes (cPPAs) are hydrophobic cyclic polymers with stimuli‐responsive depolymerization property. The introduction of hydrophilic functionalities to cPPAs is challenging due to
Liting He   +5 more
wiley   +1 more source

ANTIPROLIFERATIVE, ADME AND POTENTIAL IN SILICO G6PDH INHIBITORY ACTIVITY OF NOVEL 2-(1-BENZOFURAN-2-YL)-4-(5-PHENYL-4H-1, 2, 4-TRIAZOL-3-YL) QUINOLINE DERIVATIVES [PDF]

open access: yes, 2016
Objectives: Synthesis of new 2-(1-benzofuran-2-yl)-4-(5-phenyl-4H-1, 2, 4-triazol-3-yl) quinoline and its derivatives for antiproliferative potential against cancer cells.Methods: The general methods were employed for the synthesis and the structures ...
D., Satyanarayan N.   +7 more
core   +1 more source

Biological activities of a new compound isolated from the aerial parts of Vitex agnus castus L. [PDF]

open access: yes, 2015
A new compound trivially named vitexcarpan was isolated from the ethyl acetate fraction of Vitex agnus castus. The structure of compound was elucidated with the help of spectroscopic techniques: 13C NMR, 1H NMR, heteronuclear multiple bond correlation ...
Adhikari, A   +4 more
core   +2 more sources

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