Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles
A few 4-allyl/amino-5-aryl-1,2,4-triazoles were synthesized and tested for antibacterial and antifungal effects against Escherichia coli, Bacillus subtilis, Salmonella enteritidis, Staphylococcus aureus, Aspergillus niger and Candida albicans.
Aleksandra Buzarovska +4 more
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Metal-ligand bond lengths and strengths: are they correlated? A detailed CSD analysis [PDF]
Structure data on metal-alkoxides, metal-alcohol, metal-carboxylates, metal-carboxylic acid, metal-azolate and metal-azole coordination compounds from the Cambridge Structural Database (CSD) were analysed in terms of bond lengths.
Nimmermark, Anders +2 more
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The rearrangement of 4-methyl-3,5-diaryl-4H-1,2,4-triazoles to the corresponding 1-methyl-3,5-diaryl-1H-1,2,4-triazoles showed regioselectivity comparable to that observed for the alkylation of 3,5-diaryl-1H-1,2,4-triazoles.
Per H.J. Carlsen, Odd R. Gautun
doaj +1 more source
5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles
Herein, we present the first synthetic methodologies toward non-symmetrical 5,5′-C, C-linked bi-1,2,3-triazoles starting from 5-formyl-1,2,3-triazole via two related pathways.
Robby Vroemans +3 more
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Synthesis and physicochemical properties 4-((R))amino)-5-methyl-4H-1,2,4-triazole-3-thiols
Purposeful synthesis of derivatives of 1,2,4-triazole is one of the most important branches of modern pharmaceutical science Modern pharmaceutical market of domestic medicines requires constant updates of existing range.
T. V. Kravchenko +2 more
doaj +1 more source
Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana) [PDF]
Infectious diseases remain a significant threat to human health, contributing to more than 17 million deaths, annually. With the worsening trends of drug resistance, there is a need for newer and more powerful antimicrobial agents.
A Brüning +215 more
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Synthesis and antitumoral activity of novel biaryl hydroxy-triazole and fluorene-triazole hybrids [PDF]
Aim: The development of selective and potent antitumor agents remains a significant challenge. This study aimed to synthesize and evaluate biaryl hydroxy-1,2,3-triazoles and 9H-fluorene-1,2,3-triazole hybrids, inspired by previously identified bioactive ...
David Chafi Zeitune +6 more
doaj +1 more source
Synthesis of Bis (1,4-Disubstituted-1,2,3-triazoles) Starting from Diethyl Galactarate
This communication reports the synthesis of a series of bis (1,4-disubstituted-1,2,3-triazoles) starting from the known (2,3,4,5) bis acetonide-protected diethyl galactarate (1).
Víctor Terraza +2 more
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A brief review article: Various synthesis and therapeutic importance of 1, 2, 4-triazole and its derivatives. [PDF]
Heterocyclic compounds play an important part in medicinal chemistry. Different derivatives of heterocyclic compounds are useful for the various pharmacological activities.
MAKWANA, ATUL H +2 more
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Sustainable production and spectroscopic study of novel heterocyclic compounds synthesized from Carbendazim via green chemistry [PDF]
In this research, a series of heterocyclic compounds with both five-membered and six-membered rings were synthesized. These compounds include oxadiazole, thiadiazol, thiazole, oxadiazine, thiadiazine, and triazine, among others.
Naif Murad Hassan, Adnan Othman Omar
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