Synthesis and antitumoral activity of novel biaryl hydroxy-triazole and fluorene-triazole hybrids [PDF]
Exploration of Drug ScienceAim: The development of selective and potent antitumor agents remains a significant challenge. This study aimed to synthesize and evaluate biaryl hydroxy-1,2,3-triazoles and 9H-fluorene-1,2,3-triazole hybrids, inspired by previously identified bioactive ...
David Chafi Zeitune +6 more
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Selected 5-amino-1-aryl-1H-1,2,3-triazole scaffolds as promising antiproliferative agents [PDF]
The Ukrainian Biochemical Journal, 2020 Development of a new effective drugs with low side effects and definite chemical characteristics needs indentification of bioactive scaffolds for further structural optimization.
N. Pokhodylo +3 more
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Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety
Hacettepe University Journal of the Faculty of Pharmacy, 2022 The aim of the work was to study the antioxidant activity of 4-R-3- (morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using the method of non-enzymatic initiation of lipid peroxidation. Among the 45 compounds studied, 8 showed varying degrees of AOA.
SHCHERBYNA, Roman +5 more
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Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid [PDF]
مجلة التربية والعلم, 2009 In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles was achieved. 2-(2,3-dimethyl phenyl amino) benzoic acid was esterified to its ethyl ester by its reaction with absolute ethanol in presence of ...
Khalid Daoud +2 more
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Synthesis of substituted 1, 2, 4-triazole derivatives by Microwave irradiation [PDF]
IOSR Journal of Applied Chemistry, 2013 Various substituted Triazole-Thiol containing different functional group have been synthesized by microwave method. The title product 1-((3H-indol-2-ylamino) methyl)-4-phenyl-4, 5-dihydro-1H-1, 2, 4- triazole-3-thiol is synthesized by using amino benzothiazole.
Ashish Asrondkar +2 more
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Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
Green Processing and Synthesis, 2017 A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular ...
Kumar Surender, Sharma Dinesh Kumar
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Synthesis and Biological evalution of some substituted 2-dibenzyl amino 1,3,4-oxadiazoles , thiadiazoles and 1,2,4-triazoles [PDF]
مجلة التربية والعلم, 2013 In this paper the synthesis of some substituted 2-dibenzyl 1,3,4-oxadiazole, thiadiazole and 1,2,4-triazoles derived from dibenzyl amine is reported scheme-1.
Khalid Daoud, Shaima Ismmaeel
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Synthesis of 4-Arylselanyl-1H-1,2,3-triazoles from Selenium-Containing Carbinols
Molecules, 2021 In this work, we present a simple way to achieve 4-arylselanyl-1H-1,2,3-triazoles from selenium-containing carbinols in a one-pot strategy. The selenium-containing carbinols were used as starting materials to produce a range of selanyl-triazoles in ...
Francesca Begini +6 more
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Фармацевтичний журнал, 2018 Chemistry of heterocyclic compounds is one of the most popular sector in organic chemistry. Scientists allocate among them a class of derivatives of 1,2,4-triazole.
I. I. Aksyonova-Seliuk +2 more
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E-Journal of Chemistry, 2012 A series of novel compounds like 3[(phenyl substituted)-5-methyl-1(Benzosulphonylamine)]-1,3,4-triazole-2-ones II(a-f) were synthesized by treating 4-amino-1-phenyl-3-methyl-5-oxo-1,2,4-triazoles with benzene sulphonyl chloride using pyridine as solvent.
Mahabaleshwaraiah Neelgundmath +1 more
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