Results 61 to 70 of about 25,084 (189)
Zaporožskij Medicinskij Žurnal, 2015 Aim. To analyze the carbonyl derivatives of 7-((3-thio-4-R-4H-1,2,4-triazole-5-yl)methyl)theophylline their mother substance was synthesized and its interaction with α-haloketones series was carried out. Methods and results.
A. S. Gotsulia +3 more
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Zaporožskij Medicinskij Žurnal, 2016 The major social and economic problem of pharmaceutical industry is the search for biologically active substances, which may become the basis of new drugs, competitive with expensive imported drugs. Analysis of literature shows that in recent decades the
T. M. Kaplaushenko, O. I. Panasenko
doaj
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017 Today’s medicine and pharmacy undoubtedly need new and effective drugs. The 1,2,4-triazole derivatives occupy a special place among the wide variety of active organic compounds.
R. О. Shcherbyna
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3D-QSAR AND MOLECULAR DOCKING STUDIES ON 1, 2, 4 TRIAZOLES AS MetAP2 INHIBITORS [PDF]
, 2014 Objective: Angiogenesis inhibitors are a novel class of promising therapeutic agents for treating cancer and other human diseases. Biological transformations and pathways that play a role in angiogenesis are, therefore, particularly attractive targets as
Inturi, Bharatkumar +4 more
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“An Overview On Biological Behavior Of Benzotriazole: Synthesis And Docking Study On Its Versatile Biological Activities” [PDF]
The practice of medicinal chemistry is devoted to the discovery and development of new chemical agents for treating diseases. Triazoles are obtained by a slight modification of azole ring and similar or improved activities as well as fewer adverse ...
Divya Shirke +3 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Aim. To analyze the alkyl-, heterylderivatives of 7'-((4-ethyl-5-thio-4H-1,2,4-triazoles-3-yl)methyl)theophylline their mother substance has been synthesized and its interaction with halogenalkane and halogenheteryle has been carried out.
A. S. Gotsulya
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Synthesis and Characterization of Some 1,2,4-Triazol-4-Amino Schiff Bases of Decorated Nano Reduced Graphene Oxide With 2-Naphthol-4-Sulfonic Acid as Non-Toxic Compounds [PDF]
Purpose: This research, some derivatives were Synthesis and Characterization of Some 1,2,4-triazol-4-amino Schiff Bases of Decorated Nano Reduced Graphene Oxide with 2-naphthol-4-sulfonic acid . Methodology: In by the hummer method preparing the graphene
Al-Somaidaie, Ghazwan +2 more
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Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton [PDF]
, 2016 Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl)ethanone. Treatment of 4a,b with base afforded 1,2,4-triazoles 6a,b.
Bayrak, Hacer +6 more
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Molecules, 2008 A series of 1-acyl-4-phenyl/(acridin-9-yl)thiosemicarbazides 3, including fournew compounds, were prepared in order to study substituent effects on cyclizationreactions with oxalyl chloride (producing imidazolidine-4,5-diones 4 ...
Karel D. Klika +7 more
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SYNTHESIS, CHARACTERIZATION, AND EVALUATION OF ANTIFUNGAL PROPERTIES OF SUBSTITUTED BENZIMIDAZOLE ANALOG [PDF]
, 2018 Objective: The aim of the present study is to synthesize novel benzimidazole derivatives as potent antifungal agents.Methods: 2-chloromethyl-1H-benzimidazole has been synthesized by refluxing o-phenylenediamine with chloroacetic acid in the presence of ...
J, Anbhule Sachin, M, Vijey Aanandhi
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