Results 71 to 80 of about 29,456 (286)

Regioselectivity and Tautomerism of Novel Five-Membered Ring Nitrogen Heterocycles Formed via Cyclocondensation of Acylthiosemicarbazides

Molecules, 2008
A series of 1-acyl-4-phenyl/(acridin-9-yl)thiosemicarbazides 3, including fournew compounds, were prepared in order to study substituent effects on cyclizationreactions with oxalyl chloride (producing imidazolidine-4,5-diones 4 ...
Karel D. Klika, Marián Sabol, Jana Pisarčíková, Pavol Kristian, Stanislav Böhm, Ivan Danihel, Ján Imrich, Jana Tomaščiková   +7 more
doaj   +1 more source

3D-QSAR AND MOLECULAR DOCKING STUDIES ON 1, 2, 4 TRIAZOLES AS MetAP2 INHIBITORS [PDF]

, 2014
Objective: Angiogenesis inhibitors are a novel class of promising therapeutic agents for treating cancer and other human diseases. Biological transformations and pathways that play a role in angiogenesis are, therefore, particularly attractive targets as
Inturi, Bharatkumar, K., Bhavya, Philip, Stephen, Pujar, Gurubasavaraj V., Purohit, Madhusudan   +4 more
core   +1 more source

“An Overview On Biological Behavior Of Benzotriazole: Synthesis And Docking Study On Its Versatile Biological Activities” [PDF]

The practice of medicinal chemistry is devoted to the discovery and development of new chemical agents for treating diseases. Triazoles are obtained by a slight modification of azole ring and similar or improved activities as well as fewer adverse ...
Divya Shirke, Shivanand Kolageri, Somashekhar Metri, Vishal Babar   +3 more
core   +2 more sources

Site‐Selective Polyvinylpyrrolidone Adsorption Behavior for 3D Heterogeneous Integration

Advanced Materials Technologies, EarlyView.
Site‐selective adsorption behavior is presented with polyvinylpyrrolidone on a Cu/SiO2 pattern wafer, which enables 3D heterogeneous integration. Owing to the site‐selective adsorption behavior and its corresponding electrostatic interaction between SiO2 nanoparticles and the Cu surface, the selectivity of Cu/SiO2 is arbitrarily controlled ...
Hosin Hwang, Jinhyoung Lee, Seunghwan Lee, Ziyang Wang, Dayoung Yu, Hyeonjeong Lee, Haejin Kwak, Hyunho Kim, Myung Jun Kim, Taesung Kim   +9 more
wiley   +1 more source

Acute toxicity of 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives

Zaporožskij Medicinskij Žurnal, 2017
The purpose of our work was the further exploration of the new 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives’ acute toxicity, setting some patterns of alkyl substituents influence by the Sulfur atom on the acute ...
D. M. Danilchenko, V. V. Parchenko
doaj   +1 more source

Synthesis and Characterization of Some 1,2,4-Triazol-4-Amino Schiff Bases of Decorated Nano Reduced Graphene Oxide With 2-Naphthol-4-Sulfonic Acid as Non-Toxic Compounds [PDF]

Purpose: This research, some derivatives were Synthesis and Characterization of Some 1,2,4-triazol-4-amino Schiff Bases of Decorated Nano Reduced Graphene Oxide with 2-naphthol-4-sulfonic acid . Methodology: In by the hummer method preparing the graphene
Al-Somaidaie, Ghazwan, Mohammed, Yusra, Rashad, Safa   +2 more
core   +2 more sources

Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton [PDF]

, 2016
Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl)ethanone. Treatment of 4a,b with base afforded 1,2,4-triazoles 6a,b.
Bayrak, Hacer, Ceylan, Şule, Demirbaş, Neslihan, Mermer, Arif, Uygun, Yıldız, Özdemir, Serap Başoğlu, Ülker, Serdar   +6 more
core   +1 more source

Harnessing Carbenoid Reactivity From Imidazoles and Oxiranes

Advanced Synthesis &Catalysis, EarlyView.
The combination of azole compounds and oxiranes exhibits carbenoid reactivity at elevated temperatures, as demonstrated by the successful benzoin condensation of aromatic aldehydes. Using this catalytic system to polymerize bifunctional aldehyde/oxirane monomers yields thermosets with glass transition temperatures above 100°C.
Matthias R. Steiner, Johanna M. Uher, Jürgen Lindner, Cordula M. Zeiler, Christian Slugovc   +4 more
wiley   +1 more source

Copper-Catalyzed Synthesis of 4-CF₃-1,2,3-Triazoles: An Efficient and Facile Approach via Click Reaction

Molecules
Incorporation of a trifluoromethyl group with 1,2,3-triazoles motifs was described. We explored a click reaction approach for regioselective synthesis of 1-susbstituted-4-trifluoromethyl-1,2,3-triazoles in which 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU ...
Tinghong Tang, Cuiting Chen, Xin Fu, Huilan Xu, Luyong Wu, Wenhao Chen   +5 more
doaj   +1 more source

Synthesis and physical-chemical properties of 2-((4-R-3-(morpholinomethylen)-4H-1,2,4-triazole-5yl)thio)acetic acid

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
The creation and improvement of the original domestic medicines is anactual problem of medical and pharmaceutical industries. Chemistry of heterocyclicsystems attracts scientists all over the world, as it is associated with a number of properties of this
R. О. Shcherbyna, O. I. Panasenko, Ye. H. Knysh, B. О. Varynskyy   +3 more
doaj   +1 more source