Results 71 to 80 of about 18,771 (284)

Regioselectivity and Tautomerism of Novel Five-Membered Ring Nitrogen Heterocycles Formed via Cyclocondensation of Acylthiosemicarbazides

Molecules, 2008
A series of 1-acyl-4-phenyl/(acridin-9-yl)thiosemicarbazides 3, including fournew compounds, were prepared in order to study substituent effects on cyclizationreactions with oxalyl chloride (producing imidazolidine-4,5-diones 4 ...
Karel D. Klika, Marián Sabol, Jana Pisarčíková, Pavol Kristian, Stanislav Böhm, Ivan Danihel, Ján Imrich, Jana Tomaščiková   +7 more
doaj   +1 more source

Microwave assisted metal-free approach to access 1,2,3-triazoles through multicomponent synthesis

Current Research in Green and Sustainable Chemistry, 2020
The work illustrates multicomponent reaction of aldehydes, nitroalkanes and sodium azide for the metal-free synthesis of N-unsubstituted-1,2,3-triazoles using anthranilic acid as an organocatalyst under microwave irradiation. This is the first ever green
Anirban Garg, Diganta Sarma, Abdul Aziz Ali   +2 more
doaj  

Synthesis and physical-chemical research of 7-((3-thio-4-r-4h-1,2,4-triazole-5-yl)methyl)theophylline carbonyl derivatives

Zaporožskij Medicinskij Žurnal, 2015
Aim. To analyze the carbonyl derivatives of 7-((3-thio-4-R-4H-1,2,4-triazole-5-yl)methyl)theophylline their mother substance was synthesized and its interaction with α-haloketones series was carried out. Methods and results.
A. S. Gotsulia , P. S. Knyazevich, O. I. Panasenko, Ye. G. Knysh   +3 more
doaj   +1 more source

Regioselective Synthesis of 1-(2,6-Dichloro-4-Trifluoromethylphenyl)- 4-Alkyl-1H-[1,2,3]-Triazoles

Molecules, 2008
A new and efficient method for the synthesis of 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-alkyl-1H-[1,2,3]-triazoles by the room temperature 1,3-dipolarcycloaddition of (2-azido-1,3-dichloro-5-trifluoromethyl)benzene with terminal alkynes inthe presence
Lixue Zhang, Xinxiang Lei, Lisheng Ding, Anjiang Zhang, Huanan Hu   +4 more
doaj   +1 more source

Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo

Фармацевтичний журнал, 2018
Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
doaj   +1 more source

Modular Synthesis of Dendritic Oligo‐Glycerol Cationic Surfactants for Enhanced Antibacterial Efficacy

Angewandte Chemie International Edition, EarlyView.
An orthogonal click chemistry approach was used to synthesize a series of cationic surfactants. The results show that an optimal balance between positive charges and hydrophobicity is a crucial factor for the improvement of antibacterial properties.
Natalie Hanheiser, Yuhang Jiang, Christian Zoister, Mathias Dimde, Katharina Achazi, Chuanxiong Nie, Yuanyuan Li, Rainer Haag, Abhishek K. Singh   +8 more
wiley   +1 more source

Actoprotective properties of 7'-((3-thio-4-methyl-4H-1,2,4-triazole-5-yl)methyl)theophylline derivatives

Zaporožskij Medicinskij Žurnal, 2016
The aim of this work was the study of actoprotective activity of compounds, which combine sintons of 1,2,4-triazole-3-thiol and theophylline. Materials and methods.
A. S. Gotsulya
doaj  

Synthesis, Characterization and Antimicrobial Activity of Cu(II), Co(II) and Ni(II) Complexes with O, N, and S Donor Ligands

E-Journal of Chemistry, 2008
The complexes of the type ML2 [where M = Cu(II), Co(II), and Ni(II)] L = 1-phenyl-1-ene-3-(2-hydroxyphenyl)-prop-2-ene with 3- substituted-5-mercapto-4-amino-1,2,4-triazoles.
Vidyavati Reddy, Nirdosh Patil, S. D. Angadi   +2 more
doaj   +1 more source

Convergent Assembly of Homo‐ and Heterotypic Ubiquitin Chains from Functionalized, Expressed Monomers via Thiol‐Ene Chemistry

Angewandte Chemie International Edition, EarlyView.
Generating functionalized ubiquitin building blocks via expression in E. coli paves the way to different di‐, tri‐, and tetra‐ubiquitin chains. Light‐induced thiol‐ene click reactions, combined with a masking and protection strategy, are harnessed to establish controlled ubiquitin chain assembly and to allow the semisynthesis of site‐selectively ...
Moritz Urschbach, Susanne Huhmann, Dominik Appel, Luca Ferrari, Dominik Vogl, Sascha Martens, Christian F. W. Becker   +6 more
wiley   +1 more source

Synthesis of 4-Alkyl-4H-1,2,4-triazole Derivatives by Suzuki Cross-Coupling Reactions and Their Luminescence Properties

Molecules, 2019
New derivatives of 4-alkyl-3,5-diaryl-4H-1,2,4-triazole were synthesized utilizing the Suzuki cross-coupling reaction. The presented methodology comprises of the preparation of bromine-containing 4-alkyl-4H-1,2,4-triazoles and their coupling with ...
Monika Olesiejuk, Agnieszka Kudelko, Marcin Swiatkowski, Rafal Kruszynski   +3 more
doaj   +1 more source