Results 41 to 50 of about 37,816 (179)

Influence of 7,8 Dihydroneopterin and Hyperoxia on Neurite Growth and Tyrosine Hydroxylase Activity of PC 12 Cells

open access: yesPteridines, 2002
The influence of dihydroneopterin on tyrosine hydroxylase activity in PC 12 cells was investigated under normoxic and hyperoxic conditions, and with or without iron ions in the incubation medium.
Vrecko Karoline, Reibnegger Gilbert
doaj   +1 more source

Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways [PDF]

open access: yes, 2017
Original studyXunta de Galicia; ED431B 2016/013Xunta de Galicia; GPC2014/082Xunta de Galicia; IN607C 2016 ...
Fuchs, Dietmar   +10 more
core   +2 more sources

Neopterin-induced Suppression of Erythropoietin Production In Vitro

open access: yesPteridines, 1995
The production of neopterin increases in several diseases with activation of the ceIlular immune response. As previously shown serum concentrations of neopterin are inversely correlated with blood hemoglobin concentrations in the anemia of hematological ...
Schobersberger W.   +5 more
doaj   +1 more source

Probing the Structural Dynamics of the Plasmodium falciparum Tunneling-Fold Enzyme 6-Pyruvoyl Tetrahydropterin Synthase to Reveal Allosteric Drug Targeting Sites

open access: yesFrontiers in Molecular Biosciences, 2020
The de novo folate synthesis pathway is a well-established drug target in the treatment of many infectious diseases. Antimalarial antifolate drugs have proven to be effective against malaria, however, rapid drug resistance has emerged on the two primary ...
Afrah Khairallah   +2 more
doaj   +1 more source

Pterins as diagnostic markers of mechanical and impact-induced trauma: A systematic review [PDF]

open access: yes, 2022
We performed a systematic review of the literature to evaluate pterins as biomarkers of mechanical and impact-induced trauma. MEDLINE and Scopus were searched in March 2019.
Baxter-Parker G   +2 more
core   +1 more source

The physiological and mononuclear cell activation response to cryotherapy following a mixed martial arts contest: a pilot study

open access: yesPteridines, 2015
Cold water immersion is thought to reduce the inflammatory response to injury. Using cultured mononuclear cells and human subjects in a mixed martial arts (MMA) contest, we examined the effect of cryotherapy on 7,8-dihydroneopterin and neopterin ...
Lindsay Angus   +7 more
doaj   +1 more source

Measurement of changes in urinary neopterin and total neopterin in body builders using SCX HPLC

open access: yesPteridines, 2014
Body building is a sport where ultrastructual damage to muscle fibres aids the development of dense muscle layers. Using a new strong cation exchange (SCX) based chromatography technique to measure neopterin and 7,8-dihydroneopterin, we investigated ...
Lindsay Angus   +3 more
doaj   +1 more source

Pteridines and Lipid Metabolism

open access: yesPteridines, 1998
The effect of 9 different pteridines on fatty acid incorporation into phospholipids as well as on cholesterol and phospholipid content was compared in vitro using rat liver homogenate, Krebs-Ringer phosphate buffer containing 0.3 % albumin (pH=7.4 ...
Rudzite Vera   +5 more
doaj   +1 more source

Radical-mediated ring contraction in the biosynthesis of 7-deazapurines [PDF]

open access: yes, 2015
Pyrrolopyrimidine containing natural products are widely distributed in Nature. The biosynthesis of the 7-deazapurine moiety that is common to all pyrrolopyrimidines entails multiple steps, one of which is a complex radical-mediated ring contraction ...
Bandarian, Vahe, Drennan, Catherine L.
core   +1 more source

Neopterin, Dihydroneopterin, Tetrahydroneopterin: Different Structures-Increasing Capacity Cleaving the Porphyrin in Heme Proteins

open access: yesPteridines, 2002
Neopterin, 7,8-dihydroneopterin and 5,6,7,8-terahydroneopterm are secreted by human macrophages after activation by interferon-γ. The biological stability of the reduced pterins is less than one hour and therefore distinctly lower than that of neopterin.
Horejsi Renate   +3 more
doaj   +1 more source

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