Results 51 to 60 of about 37,102 (171)

Measurement of changes in urinary neopterin and total neopterin in body builders using SCX HPLC

Pteridines, 2014
Body building is a sport where ultrastructual damage to muscle fibres aids the development of dense muscle layers. Using a new strong cation exchange (SCX) based chromatography technique to measure neopterin and 7,8-dihydroneopterin, we investigated ...
Lindsay Angus, Janmale Tejraj, Draper Nick, Gieseg Steven P.   +3 more
doaj   +1 more source

Pteridines and Lipid Metabolism

Pteridines, 1998
The effect of 9 different pteridines on fatty acid incorporation into phospholipids as well as on cholesterol and phospholipid content was compared in vitro using rat liver homogenate, Krebs-Ringer phosphate buffer containing 0.3 % albumin (pH=7.4 ...
Rudzite Vera, Jurika Edite, Baier-Bitterlich Gabriele, Widner Bernhard, Reibnegger Gilbert, Fuchs Dietmar   +5 more
doaj   +1 more source

Mechanisms of 7,8-dihydroneopterin protection of macrophages from cytotoxicity [PDF]

, 1992
Gamma-interferon stimulates human macrophages to produce of 7,8-dihydroneopterin (7,8-NP). 7,8-NP and its oxidation product neopterin are excellent inflammatory markers for a variety of chronic conditions, including atherosclerosis.
Shchepetkina, Anastasia
core   +1 more source

Oxidant production, oxLDL uptake, and CD36 levels in human monocyte–derived macrophages are downregulated by the macrophage-generated antioxidant 7,8-dihydroneopterin.

Antioxidants and Redox Signaling, 2010
The severity of atheroma burden in patients strongly correlates to increasing levels of plasma neopterin, the oxidation product of 7,8-dihydroneopterin.
S. Gieseg, Z. Amit, Y. Yang, Anastasia A Shchepetkina, H. Katouah   +4 more
semanticscholar   +1 more source

Neopterin, Dihydroneopterin, Tetrahydroneopterin: Different Structures-Increasing Capacity Cleaving the Porphyrin in Heme Proteins

Pteridines, 2002
Neopterin, 7,8-dihydroneopterin and 5,6,7,8-terahydroneopterm are secreted by human macrophages after activation by interferon-γ. The biological stability of the reduced pterins is less than one hour and therefore distinctly lower than that of neopterin.
Horejsi Renate, Möller Reinhard, Tafeit Erwin, Reibnegger Gilbert   +3 more
doaj   +1 more source

Auto-oxidation of 5,6,7 ,8-tetrahydroneopterin

Pteridines, 1998
Auto-oxidation of 5,6,7,8-tetrahydroneopterin (NPH4 ) in phosphate buffer solution (PBS) was examined using reversed-phase high-performance liquid chromatography.
Arai Toshiyuki, Mori Hiroko, Ishii Hisanari, Suzuki Toshinori, Kojima Shuji, Mori Kenjiro   +5 more
doaj   +1 more source

The Role of Urinary Pteridines as Disease Biomarkers [PDF]

, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton, Casey, Ma, Yinfa
core   +2 more sources

Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

Pteridines, 1997
The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied.
Horejsi Renate, Daczki Jürgen, Mölller Reinhard, Öttl Karl, Vrecko Karoline, Reibnegger Gilbert   +5 more
doaj   +1 more source

Formate‐tetrahydrofolate ligase: supplying the cytosolic one‐carbon network in roots with one‐carbon units originating from glycolate

The Plant Journal, Volume 119, Issue 5, Page 2464-2483, September 2024.
SUMMARY The metabolism of tetrahydrofolate (H4PteGlun)‐bound one‐carbon (C1) units (C1 metabolism) is multifaceted and required for plant growth, but it is unclear what of many possible synthesis pathways provide C1 units in specific organelles and tissues.
Sompop Saeheng, Clayton Bailes, Han Bao, Kelem Gashu, Matt Morency, Tana Arlynn, Andrei Smertenko, Berkley James Walker, Sanja Roje   +8 more
wiley   +1 more source

Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes

BMC Cardiovascular Disorders, 2018
Background Development of collateral circulation in coronary artery disease is cardio-protective. A key process in forming new blood vessels is attraction to occluded arteries of monocytes with their subsequent activation as macrophages. In patients from
Edward C. A. Marks, Tom M. Wilkinson, Chris M. Frampton, Lorraine Skelton, Anna P. Pilbrow, Tim G. Yandle, Chris J. Pemberton, Robert N. Doughty, Gillian A. Whalley, Chris J. Ellis, Richard W. Troughton, Maurice C. Owen, Neil R. Pattinson, Vicky A. Cameron, A. Mark Richards, Steven P. Gieseg, Barry R. Palmer   +16 more
doaj   +1 more source