Effect of antimalarial drugs and malaria pigment ( *-haematin) on monocyte phagocytosis and GTP-cyclohydrolase 1 gene expression. [PDF]
, 2009 Thesis (Ph.D.)-University of KwaZulu-Natal, Pietermaritzburg, 2009.During the erythrocytic stage, the malaria parasite digests host cell haemoglobin into amino acids. Toxic haeme is released and is incorporated into an insoluble non-toxic crystal called
Cumming, Bridgette May.
core
Levels of procalcitonin, C-reactive protein and neopterin in patients with advanced HIV-1 infection [PDF]
, 2012 OBJECTIVES: To compare the value of procalcitonin, C-reactive protein (CRP) and neopterin as indicators of immune deficiency, co-infection, efficacy of treatment, and disease progression, in patients with advanced HIV-1 infection.
Bipath, Priyesh +2 more
core +1 more source
Prediction of Functional Sites Based on the Fuzzy Oil Drop Model [PDF]
, 2007 A description of many biological processes requires knowledge of the 3-D structure of proteins and, in particular, the defined active site responsible for biological function.
Ewa Stawowczyk +7 more
core +5 more sources
Synthetic and Biochemical Exploration of the Degradation and Utilization of Thiamin Analogs and Preliminary Studies on Methanopterin methyltransferase [PDF]
, 2019 Thiaminase I from Clostridium botulinum cleaves thiamin to the constituent pyrimidine and thiazole using a wide range of external nucleophiles. The crystal structure of the thiamin bound mutant of thiaminase I from Clostridium botulinum revealed the ...
Shome, Brateen
core +1 more source
The Occurrence of Folate Biosynthesis Genes in Lactic Acid Bacteria from Different Sources. [PDF]
Food Technol Biotechnol, 2023 Mahara FA +3 more
europepmc +1 more source
Urinary neopterin of wild chimpanzees indicates that cell-mediated immune activity varies by age, sex, and female reproductive status [PDF]
, 2021 Behringer, V. +3 more
core +2 more sources
Tetrahydrobiopterin Deficiency: From Phenotype to Genotype [PDF]
, 2017 As a result of the selective screening worldwide during the last 18 years, approximately 250 patients with tetrahydrobiopterin deficiency were discovered.
Blau, Nenad +3 more
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Protecting the Achilles heel : three FolE_I-type GTP-cyclohydrolases needed for full growth of metal-resistant Cupriavidus metallidurans under a variety of conditions [PDF]
In Cupriavidus metallidurans and other bacteria, biosynthesis of the essential biochemical cofactor tetrahydrofolate (THF) initiates from guanosine triphosphate (GTP).
Galeano Nuñez, Diana Carolina +3 more
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Structure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design. [PDF]
Curr Res Struct Biol, 2023 Shaw GX +5 more
europepmc +1 more source
Neopterin Levels in Periodontitis and after Nonsurgical Periodontal Therapy: Evaluation of Gingival Crevicular Fluid, Oral Fluid, Serum and Urinary Samples-A Case-Control Study. [PDF]
Biomedicines, 2022 Heneberk O +4 more
europepmc +1 more source