Results 31 to 40 of about 416 (114)

Kratom Consumption can be Addictive and have Adverse Health Effects [PDF]

Novelty in Clinical Medicine, 2022
Kratom, also known as herbal speed, is the powdered leaves of the Asian kratom tree (Mitragyna speciosa Korth.). The consumption of kratom powder or kratom tea for diarrhea, inflammation, fever, and pain, but also for anxiety and depression is based on ...
Martin Hofmeister
doaj   +1 more source

Correction to "Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for <i>μ</i>-Opioid Receptor and Opioid-Like Behavioral Effects in Rats". [PDF]

J Pharmacol Exp Ther, 2022
europepmc   +3 more sources

An evaluation of adverse drug reactions and outcomes attributed to kratom in the US Food and Drug Administration Adverse Event Reporting System from January 2004 through September 2021

Clinical and Translational Science, Volume 16, Issue 6, Page 1002-1011, June 2023., 2023
Abstract Kratom is a widely used Asian botanical that has gained popularity in the United States due to a perception that it can treat pain, anxiety, and opioid withdrawal symptoms. The American Kratom Association estimates 10–16 million people use kratom.
Xiaotong Li, Patrick Ndungu, Sanya B. Taneja, Maryann R. Chapin, Susan B. Egbert, Krishi Akenapalli, Mary F. Paine, Sandra L. Kane‐Gill, Richard D. Boyce   +8 more
wiley   +1 more source

Drug testing for mitragynine and kratom: Analytical challenges and medico‐legal considerations

Drug Testing and Analysis, Volume 15, Issue 2, Page 213-219, February 2023., 2023
The use of kratom, that is, leaves from the Southeast Asian tree Mitragyna speciosa, has spread to the Western world. Kratom contain several alkaloids including mitragynine and its three diastereomers mitraciliatine, speciogynine and speciociliatine. In Sweden, only mitragynine is classified.
Anders Helander, Alexia Rylski
wiley   +1 more source

Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder

Frontiers in Pharmacology, 2021
Background and Purpose:Mitragyna speciosa extract and kratom alkaloids decrease alcohol consumption in mice at least in part through actions at the δ-opioid receptor (δOR).
Anna M. Gutridge, Soumen Chakraborty, Balazs R. Varga, Elizabeth S. Rhoda, Alexander R. French, Alexander R. French, Arryn T. Blaine, Quinten H. Royer, Haoyue Cui, Jinling Yuan, Robert J. Cassell, Robert J. Cassell, Márk Szabó, Susruta Majumdar, Richard M. van Rijn, Richard M. van Rijn, Richard M. van Rijn   +16 more
doaj   +1 more source

A Critical Review of the Neuropharmacological Effects of Kratom: An Insight from the Functional Array of Identified Natural Compounds

Molecules, 2023
Kratom (Mitragyna speciosa Korth. Havil) has been considered a narcotic drug for years, barred by the law in many parts of the world, while extensive research over the past few decades proves its several beneficial effects, some of which are still in ...
Rahni Hossain, Abida Sultana, Manit Nuinoon, Kunwadee Noonong, Jitbanjong Tangpong, Kazi Helal Hossain, Md Atiar Rahman   +6 more
doaj   +1 more source

A systematic review of (pre)clinical studies on the therapeutic potential and safety profile of kratom in humans

Human Psychopharmacology: Clinical and Experimental, Volume 37, Issue 1, January 2022., 2022
Abstract Introduction Kratom (Mitragyna speciosa) is a tropical plant traditionally used as an ethnomedicinal remedy for several conditions in South East Asia. Despite the increased interest in its therapeutical benefits in Western countries, little scientific evidence is available to support such claims, and existing data remain limited to kratom's ...
Elisabeth Prevete, Kim Paula Colette Kuypers, Eef Lien Theunissen, Ornella Corazza, Giuseppe Bersani, Johannes Gerardus Ramaekers   +5 more
wiley   +1 more source

Plant growth and phytoactive alkaloid synthesis in kratom [Mitragyna speciosa (Korth.)] in response to varying radiance.

PLoS ONE, 2022
Leaves harvested from kratom [Mitragyna speciosa (Korth.)] have a history of use as a traditional ethnobotanical medicine to combat fatigue and improve work productivity in Southeast Asia. In recent years, increased interest in the application and use of
Mengzi Zhang, Abhisheak Sharma, Francisco León, Bonnie Avery, Roger Kjelgren, Christopher R McCurdy, Brian J Pearson   +6 more
doaj   +2 more sources

Mitragyna speciosa: Opioid Addiction Treatment and Risk of Use

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2022
Kratom (Mitragyna speciosa (Korth.) Havil.) is a plant that originated from the rainforest in Southeast Asia, mainly grows in Thailand, Malaysia, and Indonesia. Kratom has been used traditionally as an herbal remedy for the treatment of various illnesses.
Azka Muhammad Rusydan, Endang Lukitaningsih, Nanang Fakhrudin   +2 more
doaj   +1 more source

Screening and Identification of Mitragynine and 7-Hydroxymitragynine in Human Urine by LC-MS/MS [PDF]

Chromatography, 2015
Kratom is a tree planted in Southeast Asia, including Thailand, Malaysia, Myanmar (Burma) and elsewhere in the region. A long history of usage and abuse of kratom has led to the classification of kratom as a controlled substance in its native Thailand and other Southeast Asian countries.
Hanzhuo Fu, Frank Cid, Nat Dworkin, James Cocores, Gloria Shore   +4 more
openaire   +1 more source