Results 181 to 190 of about 134,460,322 (302)

Comparative Analysis of Lifecycle-Dependent A to I RNA Editing in Three Members of the <i>Microbotryum violaceum</i> Fungal Complex. [PDF]

J Fungi (Basel)
Baruri S, Shamsudeen N, Lackey ACR, Ham JP, Perlin MH.   +4 more
europepmc   +1 more source

Elevated A-to-I RNA editing in COVID-19 infected individuals. [PDF]

NAR Genom Bioinform, 2023
Merdler-Rabinowicz R, Gorelik D, Park J, Meydan C, Foox J, Karmon M, Roth HS, Cohen-Fultheim R, Shohat-Ophir G, Eisenberg E, Ruppin E, Mason CE, Levanon EY.   +12 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Epitranscriptomic Analysis of A-to-I RNA Editing and m⁶A Using Short- and Long-Read Sequencing Technologies. [PDF]

Int J Mol Sci
Brenna N, Silvestris DA, Zugaro S, Orecchini E, Crivaro E, Leo L, Gallo A.   +6 more
europepmc   +1 more source

Transcriptome-wide profiling of A-to-I RNA editing by Slic-seq. [PDF]

Nucleic Acids Res, 2023
Wei Q, Han S, Yuan K, He Z, Chen Y, Xi X, Han J, Yan S, Chen Y, Yuan B, Weng X, Zhou X.   +11 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Adenosine-to-Inosine (A-to-I) RNA Editing by ADAR1 to Control RNA Sensing in Cardiovascular Disease. [PDF]

Arterioscler Thromb Vasc Biol
Weldy CS, Li JB, Quertermous T.
europepmc   +1 more source

The Potential Regulation of A-to-I RNA Editing on Genes in Parkinson's Disease. [PDF]

Genes (Basel), 2023
Wu S, Xue Q, Qin X, Wu X, Kim P, Chyr J, Zhou X, Huang L.   +7 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Short-read RNA-seq yields lower estimates of A-to-I RNA editing levels than long-read cDNA sequencing. [PDF]

Adv Biotechnol (Singap)
Cheng S, Qi Y, Ya J, Xia L, Zhang W, Xiong Q, Liu Q, Zhang J, Song Y.   +8 more
europepmc   +1 more source