Results 171 to 180 of about 40,232 (213)

NFE2L2 rs35652124C>T polymorphism predicts Grade 4 neutropenia in esophageal cancer patients treated with docetaxel, cisplatin, and fluorouracil chemotherapy: results from exploratory and validation cohorts. [PDF]

Cancer Chemother Pharmacol
Nomura H, Suzuki T, Kojima T, Itoh K, Tsuji D.   +4 more
europepmc   +1 more source

Characterization of toxicologically significant efflux transporters and their interactions with drugs [PDF]

, 2018
Rajnai Zsuzsanna
core  

Unraveling the PFOS-NSCLC axis: integrated network toxicology, machine learning, and causal inference identify EIF4EBP1 as a key molecular hub. [PDF]

Front Public Health
Huang T, Pang H, Wang J, Guo J, Hu K, Zhou H.   +5 more
europepmc   +1 more source

Polyphyllin H Reverses Paclitaxel Resistance in Breast Cancer by Binding Membrane Cholesterol to Inhibit Both ABCB1 and ABCC3. [PDF]

Pharmaceuticals (Basel)
Ye Z, Hong C, Jiang M, Zou W, Ren Y, Li M, Xue X, Xie X, Zhang T, Ding Y.   +9 more
europepmc   +1 more source

CYP2D6 Phenotype as a Predictor of Adverse Drug Reactions in Patients Treated With Trazodone: An Explorative Pharmacogenetic Study. [PDF]

J Clin Psychopharmacol
Wiss FM, Krieg CD, Lampert ML, Meyer Zu Schwabedissen HE, Stäuble CK, Mikoteit T, Imboden C, Allemann SS.   +7 more
europepmc   +1 more source

Prenatal and postnatal atrazine-induced endocrine and ovarian chemical biotransformation protein disruption in offspring. [PDF]

J Endocr Soc
Adeyanju O, González-Alvarez ME, Antwi-Boasiako C, Laws MJ, Desaulniers AT, Keating AF.   +5 more
europepmc   +1 more source

Terpenoids: Emerging Natural Modulators for Reversing ABC Transporter-Mediated Multidrug Resistance in Cancer Chemotherapy. [PDF]

Pharmaceuticals (Basel)
Ma L, Mahemuti D, Lan Y, Xu J, Li W, Su Z, Li J, Abuduwaili A, Maimaitijiang A.   +8 more
europepmc   +1 more source

Odoribacter splanchnicus rescues aging-related intestinal P-glycoprotein damage via GDP-L-fucose secretion. [PDF]

Nat Commun
Cui C, Fang L, Li L, Lai X, Zhang R, Zhang Q, Miao R, Hu G, Zhang M, Sia JEV, Chen J, Chai H, Wu X, Lin Z, Zhang F, Li H, Zheng L, Liu D.   +17 more
europepmc   +1 more source

Identification of antibody-drug conjugate payloads that are substrates of ATP-binding cassette drug efflux transporters. [PDF]

Cancer Drug Resist
Roth JS, Guo H, Chen L, Shen M, Gbadegesin O, Robey RW, Gottesman MM, Hall MD.   +7 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL-1 inhibitor MIK665 in acute myeloid leukemia. [PDF]

Mol Oncol
Saad J, Newman R, Khabusheva E, Aakko S, Durand E, Tambe M, Kuusanmäki H, Parsons A, Miettinen JJ, Javarappa KK, Olgac EJ, Ikonen N, Kontro M, Porkka K, Maacke H, Woo J, Halilovic E, Heckman CA.   +17 more
europepmc   +1 more source