Results 121 to 130 of about 15,107 (221)

Up-regulation of ABCG1 is associated with methotrexate resistance in acute lymphoblastic leukemia cells

Frontiers in Pharmacology
Acute lymphoblastic leukemia (ALL) is a prevalent hematologic malignancy in children, and methotrexate (MTX) is a widely employed curative treatment. Despite its common use, clinical resistance to MTX is frequently encountered.
Yao Chen, Houshun Fang, Huiying Sun, Xiaoyu Wu, Yan Xu, Bin-Bing S. Zhou, Bin-Bing S. Zhou, Bin-Bing S. Zhou, Hui Li, Hui Li   +9 more
doaj   +1 more source

Association study of cholesterol-related genes in Alzheimer's disease [PDF]

, 2018
Alzheimer's disease (AD) is a genetically complex disorder, and several genes related to cholesterol metabolism have been reported to contribute to AD risk.
Barcikowska, Maria, Brouwers, Nathalie, Brundin, Rose-Marie, Brunner, Fabienne, Daniilidou, Makrina, De Deyn, Peter, Engelborghs, Sebastiaan, Giedraitis, Vilmantas, Glaser, Anna, Hedlund, Marie, Hock, Christoph, Huynh, Kim-Dung, Ingelsson, Martin, Kapaki, Elisabeth, Kilander, Lena, Kuznicki, Jacek, Lannfelt, Lars, Maruszak, Aleksandra, Molyva, Dimitra, Nitsch, Roger, Papassotiropoulos, Andreas, Paraskevas, George, Sleegers, Kristel, Thal, Dietmar, Tsolaki, Magdalini, Van Broeckhoven, Christine, Wollmer, M., Zekanowski, Cezary   +27 more
core  

[Retracted] ABCG1 as a potential oncogene in lung cancer

Experimental and Therapeutic Medicine
[This retracts the article DOI: 10.3892/etm.2017.4393.].
Tian, Chunyan, Huang, Di, Yu, Yanli, Zhang, Jihong, Fang, Qingxin, Xie, Chao   +5 more
openaire   +2 more sources

Retinal pigment epithelium cholesterol efflux mediated by the 18kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration [PDF]

, 2017
Biswas, Lincoln, Dhillon, Baljean, Graham, Annette, Shu, Xinhua, Zhou, Xinzhi   +4 more
core   +2 more sources

Characterization of the Human ABCG1 Gene [PDF]

Journal of Biological Chemistry, 2001
Matthew A. Kennedy, Asha Venkateswaran, Paul T. Tarr, Ioannis Xenarios, Jun Kudoh, Nobuyoshi Shimizu, Peter A. Edwards   +6 more
openaire   +1 more source

Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers

Lipids in Health and Disease
Background Alterations in DNA methylation (DNAm) have been observed in patients with fatty liver, but whether they are cause or consequence remains unknown.
Hailuan Zeng, Wenran Li, Mingfeng Xia, Jieyu Ge, Hui Ma, Lingyan Chen, Baishen Pan, Huandong Lin, Sijia Wang, Xin Gao   +9 more
doaj   +1 more source

ABC transzporterek vizsgálata emberi őssejtekben és a sejt-differenciálódás során = Expression and function of ABC transporters in human stem cells and during cell differentiation [PDF]

, 2011
A projektben az ABC (ATP-Binding Cassette) transzporterek kifejeződését és funkcióját vizsgáltuk emberi őssejtekben, valamint követtük a normális és daganatos sejtdifferenciálódás során bekövetkező molekuláris szintű változásokat.
Apáti, Ágota, Cserepes, Judit, Homolya, László, Laczka, Csilla, Orbán, Tamás I., Pászty, Katalin, Sarkadi, Balázs, Szabó, Katalin, Szakács, Gergely, Szebényi, Kornélia, Telbisz, Ágnes   +10 more
core  

ABCG1 Gene [PDF]

, 2020
openaire   +1 more source

USP18 Promotes Cholesterol Efflux and Mitigates Atherosclerosis by Deubiquitinating ABCG1

Journal of Cellular and Molecular Medicine
ABSTRACTDeubiquitinating enzymes (DUBs) are integral regulators of protein stability. Among these, Ubiquitin‐specific protease 18 (USP18) has emerged as a potential therapeutic target for heart failure. However, its precise role in atherosclerosis remains to be comprehensively understood.
Yang An, Chuxian Guo, Xiaoli Wang, Jiangjin Liu, Zhu Li, Jiuyang Ding, Qiaojun Zhang, Hongmei Zhou, Bing Xia, Jiawen Wang, Yanni Yu, Changwu Wan, Jie Wang, Jialin Dai   +13 more
openaire   +2 more sources

Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study

Journal of Diabetes Research
Conclusions: The interaction of the rs7901695 site of the TCF7L2 gene and the cg06500161 site of the ABCG1 gene with environmental factors may increase the risk of T2DM in Uyghurs.
Yinxia Su, Bo Shang, Xiaoyuan Hu, Zhihao Zhang, Li Wang, Kun Luo, Hua Yao, Xiangtao Liu, Yaoqin Lu, Sheng Jiang   +9 more
doaj   +1 more source