Results 101 to 110 of about 11,132 (198)

Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI

Journal of Lipid Research, 2012
To study the mechanisms of hepatic HDL formation, we investigated the roles of ABCA1, ABCG1, and SR-BI in nascent HDL formation in primary hepatocytes isolated from mice deficient in ABCA1, ABCG1, or SR-BI and from wild-type (WT) mice.
Ailing Ji, Joanne M. Wroblewski, Lei Cai, Maria C. de Beer, Nancy R. Webb, Deneys R. van der Westhuyzen   +5 more
doaj   +1 more source

The molecular mechanism of the switch of abcg1 deficient macrophages to a tumor fighting m1 phenotype

, 2019
Tümör immünolojisinin ana oyuncuları olan makrofajlar, M1 (pro-inflamatuar) ve M2 (anti- inflamatuar) makrofajlar olmak üzere iki alt gruba ayrılır.
MELTEM ALTUNAY
core  

LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells

Journal of Lipid Research, 2002
Regulation of gene expression of ATP-binding cassette transporter (ABC)A1 and ABCG1 by liver X receptor/retinoid X receptor (LXR/RXR) ligands was investigated in the human intestinal cell line CaCo-2.
Shubha Murthy, Ella Born, Satya N. Mathur, F. Jeffrey Field   +3 more
doaj   +1 more source

Calpain-mediated cleavage negatively regulates the expression level of ABCG1

Atherosclerosis, 2011
The ATP-binding cassette transporter ABCG1 mediates cholesterol efflux from macrophages, and prevents the progression of macrophage foam-cell formation. Much less is known about the regulatory mechanism of ABCG1, although its physiological importance is becoming clearer.
Hori, Natsuki, Hayashi, Hisamitsu, Sugiyama, Yuichi   +2 more
openaire   +2 more sources

Solubility of ABCA1, ABCG1, and ABCG4 treated with Triton X-100 and Brij 96.

, 2014
HEK293, HEK/ABCA1, HEK/ABCG1, or HEK/ABCG4 cells were treated with 1% Triton X-100 (A) or Brij 96 (B), and separated into soluble (S) and insoluble (IS) fractions by centrifugation. The soluble and insoluble fractions (5 µg of proteins) were separated by
Aya Kobayashi (642543), Michinori Matsuo (169167), Shiho Ito (642542), Kazumitsu Ueda (169170), Osamu Sano (642541), Yuji Shimizu (174369), Reiko Kato (372943), Noriyuki Kioka (169174), Yasuhisa Kimura (642544), Kentaro Hanada (207598)   +9 more
core   +1 more source

Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers

Lipids in Health and Disease
Background Alterations in DNA methylation (DNAm) have been observed in patients with fatty liver, but whether they are cause or consequence remains unknown.
Hailuan Zeng, Wenran Li, Mingfeng Xia, Jieyu Ge, Hui Ma, Lingyan Chen, Baishen Pan, Huandong Lin, Sijia Wang, Xin Gao   +9 more
doaj   +1 more source

Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study

Journal of Diabetes Research
Conclusions: The interaction of the rs7901695 site of the TCF7L2 gene and the cg06500161 site of the ABCG1 gene with environmental factors may increase the risk of T2DM in Uyghurs.
Yinxia Su, Bo Shang, Xiaoyuan Hu, Zhihao Zhang, Li Wang, Kun Luo, Hua Yao, Xiangtao Liu, Yaoqin Lu, Sheng Jiang   +9 more
doaj   +1 more source

Characterization of the Human ABCG1 Gene [PDF]

Journal of Biological Chemistry, 2001
Matthew A. Kennedy, Asha Venkateswaran, Paul T. Tarr, Ioannis Xenarios, Jun Kudoh, Nobuyoshi Shimizu, Peter A. Edwards   +6 more
openaire   +1 more source

Dysfunction of the ABCA1 and ABCG1 Transporters and Their Impact on HDL Metabolism

Antioxidants
High-density lipoprotein (HDL) metabolism depends on several key factors, including ATP-binding cassette (ABC) transporters such as ABCA1 and ABCG1. These transporters are essential for maintaining cholesterol homeostasis by mediating the efflux of cellular lipids and promoting HDL formation and maturation. Dysfunction in these pathways compromises HDL
Kevin David Laguna-Maldonado, Daniel Uribe-Ramírez, Melissa Vázquez-Carrada, Deyamira Matuz-Mares, María Magdalena Vilchis-Landeros   +4 more
openaire   +3 more sources

Identification of ABCA1 and ABCG1 in milk fat globules and mammary cells--implications for milk cholesterol secretion

, 2011
The ATP-binding cassette (ABC) transporters ABCA1 and ABCG1 play an important role in cellular cholesterol homeostasis, but their function in mammary gland (MG) tissue remains elusive.
O. Mani, M.T. Sorensen, C. Albrecht, Sejrsen, K, C.E. Ontsouka, Mani, O, Körner, M, Ontsouka, C E, Albrecht, C, R.M. Bruckmaier, Sorensen, M T, K. Sejrsen, M. Körner, Bruckmaier, R M, Bruckmaier, Rupert, Sejrsen K, Sorensen MT, Mani O, Bruckmaier RM, Albrecht C, Albrecht, Christiane, Körner M, Körner Jachertz, Meike, Ontsouka CE   +23 more
core   +1 more source