Results 161 to 170 of about 11,132 (198)
The Reentry Helix Is Potentially Involved in Cholesterol Sensing of the ABCG1 Transporter Protein
International Journal of Molecular Sciences, 2022 ABCG1 has been proposed to play a role in HDL-dependent cellular sterol regulation; however, details of the interaction between the transporter and its potential sterol substrates have not been revealed.
Tamás Hegedűs, László Homolya
exaly +2 more sources
Expression and Functional Characterization of ABCG1 Splice Variant ABCG1(666) [PDF]
FEBS Letters, 2006 The ATP‐binding cassette transporter ABCG1 mediates the transport of excess cholesterol from macrophages and other cell types to high density lipoprotein (HDL) but not to lipid‐depleted apolipoprotein AI. Several splice variants which may have different functions have been identified in mammals.
Udo Seedorf +2 more
exaly +3 more sources
Structure and Transport Mechanism of the Human Cholesterol Transporter ABCG1 [PDF]
Cell Reports, 2022 The reverse cholesterol transport pathway is responsible for the maintenance of human cholesterol homeostasis, an imbalance of which usually leads to atherosclerosis. As a key component of this pathway, the ATP-binding cassette transporter ABCG1 forwards cellular cholesterol to the extracellular acceptor nascent high-density lipoprotein (HDL). Here, we
Xuebiao Yao, Cong-Zhao Zhou, Yuxing Chen
exaly +4 more sources