Role of the ABCG2 transporter in the biodistribution of the food-borne uremic toxin p-cresyl sulfate
The ATP-binding cassette transporter G2 (ABCG2) is a membrane transporter that conditions pharmacokinetics, systemic exposure, and milk secretion of drugs, natural and food-derived compounds, including gut-derived metabolites.
Alicia Millán-García +7 more
doaj +1 more source
人原发性肝癌细胞ABCG2+表型的检测、分离及其生物学特性的初步研究
目的检测人原发性肝癌ABCG2+亚群细胞并加以分离,对其生物学特性进行初步研究。方法通过PE-ABCG2单克隆抗体标记,流式细胞仪检测、分选ABCG2+细胞,体外培养后进行细胞周期、增殖活性和凋亡的检测。结果原发性肝癌细胞中存在ABCG2+表型,占细胞总数的1.3%;体外培养24 hours,ABCG2+表型有81.48%处于细胞周期的G0/G1期,non-ABCG2-表型为46.05%;ABCG2+表型凋亡率为11.5%,non-ABCG2-为27.9%;体外连续培养7天,ABCG2 ...
doaj
Identification of the Acetamide-Chalcone Derivative That Selectively Inhibits ABCG2 Transport Activity. [PDF]
Gomes de Oliveira AH +10 more
europepmc +1 more source
Pregestational Body Mass Index Is Associated with Differential Expression of ABC Transporter in the Maternal-Neonatal Dyad. [PDF]
Vanoye-Carlo A +7 more
europepmc +1 more source
Liver enzyme elevations during statin-ezetimibe therapy in <i>ABCG2</i> c.421C>A variant carriers: a case series and narrative review. [PDF]
Šimičević L +6 more
europepmc +1 more source
ABCG2 and ABCC2 Expression Levels and Their Relationship With Disease Severity in Acute Pancreatitis. [PDF]
Baş S +7 more
europepmc +1 more source
Response to "Natural Coumarins as ABC Transporters Modulators: A Key Mechanistic Question for Osteosarcoma Chemotherapy". [PDF]
Azadbeigi P +4 more
europepmc +1 more source
Natural Coumarins as ABC Transporters Modulators: A Key Mechanistic Question for Osteosarcoma Chemotherapy. [PDF]
Ren SH.
europepmc +1 more source
Identification of ion homeostasis-related genes as diagnostic biomarkers for pulmonary arterial hypertension via WGCNA and machine learning. [PDF]
Chen Y, Chen Q, Zheng S.
europepmc +1 more source

