Results 31 to 40 of about 5,034 (216)

Mechanistic insights into the neutralization of cytotoxic abrin by the monoclonal antibody D6F10. [PDF]

open access: yesPLoS ONE, 2013
Abrin, an A/B toxin obtained from the Abrus precatorius plant is extremely toxic and a potential bio-warfare agent. Till date there is no antidote or vaccine available against this toxin.
Shradha Bagaria   +3 more
doaj   +1 more source

Blood microsampling technologies: Innovations and applications in 2022

open access: yesAnalytical Science Advances, Volume 4, Issue 5-6, Page 154-180, July 2023., 2023
Abstract With the development of highly sensitive bioanalytical techniques, the volume of samples necessary for accurate analysis has reduced. Microsampling, the process of obtaining small amounts of blood, has thus gained popularity as it offers minimal‐invasiveness, reduced logistical costs and biohazard risks while simultaneously showing increased ...
Manchu Umarani Thangavelu   +4 more
wiley   +1 more source

Medicinal Plants Used in the Management of Sexual Dysfunction, Infertility and Improving Virility in the East African Community: A Systematic Review

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Sexual disorders such as erectile dysfunction (ED), sterility, and sexual inappetence represent some of the complex reproductive challenges that require addressing the underlying causes. The aim of this paper was to systematically synthesize literature on the ethnobotany, phytochemistry, bioactivities, and safety of plants used as remedies for managing
Christine Kyarimpa   +7 more
wiley   +1 more source

Naturally Occurring Plant Food Toxicants and the Role of Food Processing Methods in Their Detoxification

open access: yesInternational Journal of Food Science, Volume 2023, Issue 1, 2023., 2023
Some plant foods evolve defense mechanisms to protect themselves from predators by producing inherent chemicals as secondary metabolites such as cyanogenic glycosides, glycoalkaloids, glucosinolates, pyrrolizidine alkaloids, and lectins. These metabolites are beneficial for the plant itself but toxic to other organisms, including human beings.
Markos Makiso Urugo   +2 more
wiley   +1 more source

Complete genome sequence and phylogenetic analysis of medicinal plant Abrus cantoniensis for evolutionary research and germplasm utilization

open access: yesThe Plant Genome, Volume 15, Issue 3, September 2022., 2022
Abstract Abrus cantoniensis Hance, a native medicinal plant in southern China, is officially recorded in the Chinese Pharmacopoeia. Here, we presented the first high‐quality genome in Abrus genus, A. cantoniensis genome, as well as the detailed genomic information.
Shiqiang Xu   +5 more
wiley   +1 more source

Surface‐enhanced Raman scattering: An emerging tool for sensing cellular function

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 14, Issue 4, July/August 2022., 2022
SERS is a rapid, ultrasensitive, noninvasive, and versatile technique for biomedical and diagnostics applications. Abstract Continuous long‐term intracellular imaging and multiplexed monitoring of biomolecular changes associated with key cellular processes remains a challenge for the scientific community.
Swati Tanwar   +3 more
wiley   +1 more source

Effect of Abrin on Peptide Chain Initiation [PDF]

open access: bronzeEuropean Journal of Biochemistry, 1977
Cell‐free systems from wheat germ were preincubated before and after addition of immunoglobulin mRNA to generate systems dependent and independent on peptide chain initiation, respectively. When abrin A chain was added, the system dependent on peptide chain initiation was much more strongly inhibited than the system measuring primarily chain elongation.
Jon Skorve   +3 more
openalex   +4 more sources

Abrine Elicits Liver Carcinoma Immunity and Enhances Antitumor Efficacy of Immune Checkpoint Blockade by Modulating PD‐L1 Signaling

open access: yesJournal of Oncology, Volume 2022, Issue 1, 2022., 2022
Background. Liver cancer is the most malignant type of human malignancies. In recent years, immune therapy that targets the immune check points such as programmed cell death ligand 1 (PD‐L1) has achieve great success. Abrine is the dominant alkaloid in Abrus cantoniensis and Abrus precatorius Linn. that exhibited anticancer effect.
Shaowu Zhang, Shangxiang Chen
wiley   +1 more source

A Systematic Review of Medicinal Plants of Kenya used in the Management of Bacterial Infections

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Kenya’s vision 2030 partly aims at ensuring adequate health care for all, and the integration of traditional healthcare practices into the national healthcare system would present a more rapid alternative towards the realization of universal health coverage in Kenya.
Elizabeth A. Odongo   +4 more
wiley   +1 more source

Nano‐Oncologicals: A Tortoise Trail Reaching New Avenues

open access: yesAdvanced Functional Materials, Volume 31, Issue 44, October 26, 2021., 2021
This is a critical review of the applications of nanotechnology for the improvement of oncological treatments based both on synthetic and biological molecules to target either tumor or immune cells. An overview of the early beginnings of the field, together with the most relevant formulations in clinical and preclinical evaluation, is also provided ...
Tamara G. Dacoba   +8 more
wiley   +1 more source

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