Results 41 to 50 of about 1,975 (144)

Scallop mantle toxin induces apoptosis in liver tissues of mice

Food Science &Nutrition, Volume 8, Issue 7, Page 3308-3316, July 2020., 2020
We had previously shown that the intake of scallop mantle tissue resulted in the death of mice and rats. In this study, we have investigated how liver tissue injuries are caused by the mantle toxin. Our results showed that the mantle toxin caused liver tissue apoptosis through the induction of oxidative stress, ER stress, and inflammation in the organ.
Takahide Kariya, Yasushi Hasegawa
wiley   +1 more source

CCD Based Detector for Detection of Abrin Toxin Activity

Toxins, 2020
Abrin is a highly potent and naturally occurring toxin produced in the seeds of Abrus precatorius (Rosary Pea) and is of concern as a potential bioterrorism weapon.
Reuven Rasooly, Paula Do, Bradley Hernlem   +2 more
doaj   +1 more source

Plant‐Derived Lectins as Potential Cancer Therapeutics and Diagnostic Tools

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
Cancer remains a global health challenge, with high morbidity and mortality, despite the recent advances in diagnosis and treatment. Multiple compounds assessed as novel potential anticancer drugs derive from natural sources, including microorganisms, plants, and animals. Lectins, a group of highly diverse proteins of nonimmune origin with carbohydrate‐
Milena Mazalovska, J. Calvin Kouokam, Yearul Kabir   +2 more
wiley   +1 more source

Phage Display Affibodies Combined with AuNPs@Ru(bpy)₃²⁺ for Ultra-Sensitive Electrochemiluminescence Detection of Abrin

Chemosensors, 2022
Abrin is a cytotoxin with strong lethality, which is a serious threat to human health and public safety, and thus, highly sensitive detection methods are urgently needed.
Shuai Liu, Zhaoyang Tong, Chunying Jiang, Chuan Gao, Jianjie Xu, Xihui Mu, Bing Liu, Bin Du, Zhiwei Liu, Pengjie Zhang   +9 more
doaj   +1 more source

Abrin Toxicity and Bioavailability after Temperature and pH Treatment

Toxins, 2017
Abrin, one of most potent toxins known to man, is derived from the rosary pea (jequirity pea), Abrus precatorius and is a potential bioterror weapon.
Christina C. Tam, Thomas D. Henderson, Larry H. Stanker, Xiaohua He, Luisa W. Cheng   +4 more
doaj   +1 more source

Simultaneous Detection of Ricin and Abrin DNA by Real-Time PCR (qPCR)

Toxins, 2012
Ricin and abrin are two of the most potent plant toxins known and may be easily obtained in high yield from the seeds using rather simple technology. As a result, both toxins are potent and available toxins for criminal or terrorist acts. However, as the
Roman Wölfel, Mirko Lange, Ilona Mossbrugger, Eva Felder   +3 more
doaj   +1 more source

A Monoclonal–Monoclonal Antibody Based Capture ELISA for Abrin

Toxins, 2017
Abrin, one of the most highly potent toxins in the world, is derived from the plant, Abrus precatorius. Because of its high toxicity, it poses potential bioterror risks.
Christina C. Tam, Luisa W. Cheng, Xiaohua He, Paul Merrill, David Hodge, Larry H. Stanker   +5 more
doaj   +1 more source

A biophysical elucidation for less toxicity of Agglutinin than Abrin-a from the Seeds of Abrus Precatorius in consequence of crystal structure

Journal of Biomedical Science, 2010
X-ray crystal structure determination of agglutinin from abrus precatorius in Taiwan is presented. The crystal structure of agglutinin, a type II ribosome-inactivating protein (RIP) from the seeds of Abrus precatorius in Taiwan, has been determined from ...
Liu Chao-Lin, Lu Tian-Huey, Cheng Jack, Lin Jung-Yaw   +3 more
doaj   +1 more source

Risks for human health related to the presence of plant lectins in food

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The European Commission asked the European Food Safety Authority (EFSA) to assess the risk related to the presence of plant lectins in food. Based on the available evidence, the CONTAM Panel considered only phytohaemagglutinin (PHA), a legume lectin from beans (Phaseolus sp.), for the risk characterisation.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Isabelle P. Oswald, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Hanne Frøkiær, Bettina Grasl‐Kraupp, Patrick Mulder, Pierre Rougé, Heather Wallace, Marios Georgiadis, José Ángel Gómez Ruiz, Eirini Kouloura, Olaf Mosbach‐Schulz, Lydia Alarcón Asensio, Eleni Gkimprixi, Evangelia Ntzani   +30 more
wiley   +1 more source

From WGS to gels: Development and testing of PCR primers targeting toxic Digitalis in support of food safety

Applications in Plant Sciences, Volume 13, Issue 5, September-October 2025.
Abstract Premise This study capitalized on a library of single‐nucleotide polymorphisms created via whole genome sequencing (WGS) to develop and test a PCR assay for detecting toxic Digitalis species in food products. Complex foods can be difficult to analyze, but safeguarding consumer well‐being and public health necessitates that products regulated ...
Elizabeth Sage Hunter, Sydnee Fo, Robert Literman, Richard H. Uva, Jennifer L. Wolny, Sara M. Handy   +5 more
wiley   +1 more source