Results 1 to 10 of about 1,222 (132)

Safety and Efficacy of Repurposed Smallpox Vaccines Against Mpox: A Critical Review of ACAM2000, JYNNEOS, and LC16 [PDF]

Journal of Epidemiology and Global Health
Since 2022, outbreaks of monkeypox (Mpox), which is caused by the monkeypox virus (MPXV), have been documented in more than 116 nations, making it a serious danger to world health.
Alfonso J. Rodríguez-Morales, Shafiul Haque, Faraz Ahmad   +2 more
exaly   +5 more sources

Comparison of Biological, Pharmacological Characteristics, Indications, Contraindications and Adverse Effects of JYNNEOS and ACAM2000 Monkeypox Vaccines

Vaccines, 2022
Human monkeypox is an emerging viral zoonotic disease, that has caused highly distinctive, challenging and threatening problems worldwide. The US Food and Drug Administration (FDA) has given interim authorization for the JYNNEOS and ACAM2000 vaccines for
Sultan Ayoub Meo, Thamir Al-Khlaiwi
exaly   +5 more sources

A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB, Hanif A, Ahmad S, Shah FI, Javed B, Javed B, Iqbal S.   +6 more
europepmc   +2 more sources

Trends of Pathogenicity and Potential Risk Evaluation of Central African Mpox Variant to Cause Global Public Health Emergency: A Cross-Sectional Analysis. [PDF]

Health Sci Rep
ABSTRACT Background With the re‐emergence of monkeypox (Mpox), it is vital for communities to assess and effectively respond to emerging outbreaks. This paper aims to review the potential of clade I Mpox to result in a widespread outbreak by assessing genetically enhanced virulence, transmission, and clinical manifestations.
Rahman MA, Kozlowich C, Katulka N, Thomas MR, Shanjana Y, Islam MR.   +5 more
europepmc   +2 more sources

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics. [PDF]

MedComm (2020)
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yan Y, Sun Y, Sun G, Niu C, Zhao X, Zhao M, Liu T, Zhang S, Zhai H, Liu A, Yu S, Pan S, Zhong W, Zhang Y, Li S.   +14 more
europepmc   +2 more sources

Mpox in South Asia: A Narrative Review on Epidemiology, Preparedness, and Preventive Strategies. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Monkeypox (Mpox), due to its growing global concern, was declared a public health emergency of worldwide concern by the World Health Organization in August 2024. The monkeypox virus (MPXV), once limited to African regions, has now spread to South Asia, including Pakistan, India, Nepal, and Sri Lanka, and there have been ...
Mawa J, Rimun SN, Rahman NZ, Bhuiyan MA, Shahriar M, Anjum R.   +5 more
europepmc   +2 more sources

The Role of Public Health Interventions and Control Measures During Mpox Outbreaks: Enhancing Strategies for Disease Prevention and Management. [PDF]

Public Health Chall
This paper highlights key public health interventions and control strategies implemented during mpox outbreaks, emphasizing early detection, targeted prevention, and the role of vaccination and education in mitigating disease transmission. ABSTRACT Mpox (formerly—monkeypox) is the second viral pit break after COVID‐19.
Faheem MSB, Khan AA, Faheem Q, Ain HQU, Imam W, Aimen Y, Ahmed R.   +6 more
europepmc   +2 more sources

Mpox (Monkeypox) in Pregnancy Updates. [PDF]

Health Sci Rep
ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Dorjey Y, Chhetri DK.
europepmc   +2 more sources

Emerging threats of monkeypox virus in 2024: current insights and future directions [PDF]

Future Science OA
Monkeypox has reemerged as a major global public health threat, with 2024 witnessing the rise of Clade Ib, a new, more transmissible and potentially severe variant.
Dhivya L. S., Divya R., Monisha A., Harikrishnan N., Rukaiah Fatma Begum, Nirenjen S., Manisha M., Ankul Singh S.   +7 more
doaj   +2 more sources

Genomic variability and immunological aspects involved in response to MPXV infection [PDF]

Frontiers in Pharmacology
Mpox, caused by the monkeypox virus (MPXV), is a zoonotic disease that has gained global relevance after the 2022–2024 outbreak. MPXV exists in two distinct clades: clade I, associated with higher virulence and mortality, and clade II, which demonstrated
Simone La Frazia, Anna Rosa Garbuglia, Silvia Pauciullo, Verdiana Zulian, Paola Del Porto   +4 more
doaj   +2 more sources