Monkeypox in Patient Immunized with ACAM2000 Smallpox Vaccine During 2022 Outbreak
Emerging Infectious Diseases, 2022 We report a case of monkeypox in the United States in a patient who had been vaccinated with ACAM2000 smallpox vaccine 8 years earlier. Despite his vaccination status, he still contracted disease.
Matthew Turner +5 more
doaj +3 more sources
Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Objectives: We compared rates of myopericarditis adverse events and evaluated potential risk factors of development. We compared rates of dermatological–neurological adverse events (severe and serious) with other adverse events in a specific population ...
Kevin Yeo +9 more
doaj +2 more sources
ACAM2000™: The new smallpox vaccine for United States Strategic National Stockpile
Drug Design, Development and Therapy, 2010 Aysegul Nalca, Elizabeth E ZumbrunCenter for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, MD, USAAbstract: Smallpox was eradicated more than 30 years ago, but heightened concerns over ...
Aysegul Nalca, Elizabeth E Zumbrun
doaj +6 more sources
IMVAMUNE® and ACAM2000® Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model [PDF]
Vaccines, 2020 The protection provided by smallpox vaccines when used after exposure to Orthopoxviruses is poorly understood. Postexposu re administration of 1st generation smallpox vaccines was effective during eradication.
M. Shannon Keckler +10 more
doaj +3 more sources
Pathological skin manifestations following smallpox vaccination (ACAM2000) in US military personnel, 2009–2023: a systematic review [PDF]
Baylor University Medical Center ProceedingsIn the aftermath of anthrax bioterrorism, the US military began its smallpox immunization program in 2002. Dryvax was superseded in 2008 by ACAM2000, a second-generation smallpox vaccine, after clinical trials demonstrated favorable outcomes. However, these trials focused on significant adverse effects and provided less specific classifications and ...
Shafi Rehman
exaly +4 more sources
A new attenuated and highly immunogenic orthopoxvirus vaccine protects against mpox in mice and macaques [PDF]
npj VaccinesShortly after 2022, mpox again becomes a public health emergency of international concern as declared by the World Health Organization on August 14, 2024.
Fengwen Xu +23 more
doaj +2 more sources
Insights into Monkeypox Virus: Host Immunity, Viral Immune Evasion, Recent Advances in Vaccines, Therapeutic Development, and Future Perspectives [PDF]
MicroorganismsMonkeypox (Mpox), a zoonotic viral disease caused by the Monkeypox Virus (MPXV), has gained significant attention in recent years due to its increasing incidence and the grave threat it poses to global health.
Mingzhuo Chen +7 more
doaj +2 more sources
Mpox: Global epidemic situation and countermeasures [PDF]
VirulenceMpox, is a zoonotic disease caused by the monkeypox virus and is primarily endemic to Africa. As countries gradually stop smallpox vaccination, resistance to the smallpox virus is declining, increasing the risk of infection with mpox and other viruses ...
Wenshuang Hou +6 more
doaj +2 more sources
Monkeypox pandemic containment: does the ACAM2000 vaccine play a role in the current outbreaks?
Expert Review of Vaccines, 2023 Basant E. Katamesh +3 more
doaj +3 more sources
Monkeypox (Mpox): a comprehensive review of epidemiology, therapeutic advances, and public health implications [PDF]
Journal of Health, Population and NutritionBackground Monkeypox, a zoonotic viral disease caused by the monkeypox virus (MPXV), was first identified in captive monkeys in 1958 and in humans in 1970.
Amit Verma +6 more
doaj +2 more sources