When a Bulbar Ulcer Hides a Darker Reality: The Unusual Diagnosis of a Portal Cavernoma in a 69-Year-Old Adult. [PDF]
ABSTRACT A portal cavernoma is a network formed by localized dilation of the hepatic portal system. This study aims to describe a case of portal cavernoma in a 69‐year‐old adult presenting with gastrointestinal hemorrhage. This is a 69‐year‐old patient with no particular medical history admitted for hematemesis associated with diffuse abdominal pain ...
Nacanabo MW +13 more
europepmc +2 more sources
Challenging Anticoagulation With Warfarin and Heparin Following Mechanical Mitral Valve Replacement in a Patient With Infective Endocarditis: A Case Report Highlighting Diagnostic Difficulties. [PDF]
ABSTRACT Warfarin remains the cornerstone of anticoagulation therapy following mechanical heart valve replacement. However, challenging anticoagulation responses, resistance to warfarin, and even more rarely to both warfarin and heparin pose significant clinical challenges and complicate management strategies.
Khan M +9 more
europepmc +2 more sources
Methodological Concerns Regarding a Recent Meta-Analysis of Direct Oral Anticoagulants Versus Vitamin K Antagonists in Non-Valvular Atrial Fibrillation. [PDF]
Clinical Cardiology, Volume 49, Issue 5, May 2026.
Samir OK, Datta N.
europepmc +2 more sources
Safety and Efficacy of Direct Oral Anticoagulants Versus Vitamin K Antagonists for Cerebrovascular Ischemic Outcomes in Non-Valvular Atrial Fibrillation: A Systematic Review and Meta-Analysis. [PDF]
Direct Oral Anticoagulants (DOACs) were associated With lower rates of cerebrovascular ischemic events and major bleeding compared With Vitamin K antagonists in non‐valvular atrial fibrillation, With similar mortality. These findings support DOACs as the preferred anticoagulant strategy for stroke prevention in contemporary clinical practice.
Nasir A +8 more
europepmc +2 more sources
SAFETY OF TEETH EXTRACTIONS IN PATIENTS ON ACENOCOUMAROL THERAPY [PDF]
Introduction: Studies evaluating bleeding risk in anticoagulated patients undergoing dental surgical procedures have been conducted for more than 50 years and are still ongoing.
Atanaska Dinkova, Hristo Daskalov
doaj +1 more source
The development of a proof-of-concept point-of-care (PoC) device for the determination of oral anticoagulants determination is presented. Acenocoumarol (ACL) is prescribed to prevent certain cardiovascular diseases related to the prevention of deep vein ...
J.-Pablo Salvador +5 more
doaj +1 more source
OPINION SURVEY OF THE CARDIOLOGISTS IN BULGARIA REGARDING THERAPY WITH ACETYLSALICYLIC ACID, CLOPIDOGREL AND ACENOCOUMAROL IN PATIENTS UNDERGOING DENTAL EXTRACTIONS [PDF]
Purpose: Cardiovascular diseases are the leading cause of mortality and disability worldwide. Major role in the treatment and prophylaxis of these diseases and their complications has antiplatelet and anticoagulation therapy. Routine practice in the past
Atanaska Dinkova +2 more
doaj +1 more source
Clozapine-Associated Pulmonary Embolism: Continuation of Clozapine Therapy With Concurrent Anticoagulation. [PDF]
Clozapine, a gold standard for treatment‐resistant schizophrenia, is associated with a range of adverse effects, including the rare but serious risk of pulmonary embolism (PE). The management of such complications, particularly in the absence of clear guidelines for preventive anticoagulation, poses significant challenges.
Jahangir MR +4 more
europepmc +2 more sources
Background and objectives: Patients with heart failure (HF) often present with non-valvular atrial fibrillation and require oral anticoagulation with coumarin anticoagulants such as acenocoumarol.
Rubén Ángel Martín-Sánchez +12 more
doaj +1 more source
Aim: Healthcare resources usage and costs associated to nonvalvular atrial fibrillation (NVAF) were analyzed in Spain. Methods: This is an observational and retrospective study on patients with NVAF who started their treatment with apixaban or ...
Josep Comin Colet +6 more
doaj +1 more source

