Results 111 to 120 of about 113,995,962 (231)

A horizontally acquired pantothenate gene drives vitellogenin's benefit to whitefly symbiosis persistence

Insect Science, EarlyView.
This diagram illustrates that the horizontally transferred panBC influences the level and localization of vitellogenin (Vg) by facilitating pantothenate production and juvenile hormone (JH) biosynthesis. In turn, Vg shields symbionts by suppressing autophagic degradation in bacteriocytes.
Xiang Sun, Bing‐Qi Liu, Zhan‐Bo Chen, Chu‐Qiao Li, Xing‐Ye Li, Jun‐Bo Luan   +5 more
wiley   +1 more source

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention. [PDF]

Cell Chem Biol, 2022
Summers RL, Pasaje CFA, Pisco JP, Striepen J, Luth MR, Kumpornsin K, Carpenter EF, Munro JT, Lin, Plater A, Punekar AS, Shepherd AM, Shepherd SM, Vanaerschot M, Murithi JM, Rubiano K, Akidil A, Ottilie S, Mittal N, Dilmore AH, Won M, Mandt REK, McGowen K, Owen E, Walpole C, Llinás M, Lee MCS, Winzeler EA, Fidock DA, Gilbert IH, Wirth DF, Niles JC, Baragaña B, Lukens AK.   +33 more
europepmc   +1 more source

Mechanistic investigations of the A-cluster of acetyl-CoA synthase

, 2006
The A-cluster of acetyl-CoA synthase (ACS) catalyzes the formation of acetyl- CoA from CO, coenzyme-A, and a methyl group donated by a corrinoid iron-sulfur protein.
Bramlett, Matthew Richard
core   +1 more source

A horizontally transferred bacterial gene for pantothenic acid biosynthesis regulates diapause and reproduction in the spider mite Amphitetranychus viennensis

Insect Science, EarlyView.
A bacterial‐derived AvPBL gene encoding a pantothenate‐β‐alanine ligase was identified in Amphitetranychus viennensis. RNAi silencing of AvPBL reduced pantothenic acid production, impairing reproduction and diapause induction, while pantothenic acid supplementation rescued these phenotypes.
Meibin Liu, Yifei Wang, Yikang Ren, Fan Yang, Meifeng Ren, Qin Yu, Xuguo Zhou, Zezhong Yang, Jing Yang   +8 more
wiley   +1 more source

Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells. [PDF]

Cancer Commun (Lond), 2022
Han JH, Kim YK, Kim H, Lee J, Oh MJ, Kim SB, Kim M, Kim KH, Yoon HJ, Lee MS, Minna JD, White MA, Kim HS.   +12 more
europepmc   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Functional Conversion of Acetyl-Coenzyme a Synthase to a Nickel Superoxide Dismutase via Rational Design of Coordination Microenvironment for the Ni_d-Site. [PDF]

Int J Mol Sci, 2022
Wei Y, Zhou Y, Yuan H, Liu Y, Lin YW, Su J, Tan X.   +6 more
europepmc   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Human N-Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and N-Hydroxy-Arylamine Carcinogens. [PDF]

Front Pharmacol, 2022
Hein DW, Doll MA, Habil MR.
europepmc   +1 more source

Investigations into β-ketoacyl-ACP Synthase III and enoyl-ACP reductase of plant fatty acid synthase [PDF]

, 1999
An antisense transgenic approach was taken in order to assess the importance of P-ketoacyl-ACP- Synthase III (KAS III) in regulation and initiation of de novo fatty acid synthesis in planta.
Clarke, Hayley Diana
core