Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model
Nutrition Journal, 2010 Background/Aims Matrix Metalloproteinases 2 is a key molecule in cellular invasion and metastasis. Mitochondrial ROS has been established as a mediator of MMP activity. Coenzyme Q10 contributes to intracellular ROS regulation.
Mirmiranpour Hossein +6 more
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Sensitivity of forage turnip to the herbicide tepraloxydim
Revista Ceres, 2020 The objective of this study was to evaluate the responses of Raphanus sativus to the application of the herbicide tepraloxydim by analyzing photosynthetic and biometric characteristics of the plants.
Gabriel Martins Almeida +4 more
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Depletion of ATP-citrate lyase (ATPCL) affects chromosome integrity without altering histone acetylation in Drosophila mitotic cells [PDF]
, 2019 The Citrate Lyase (ACL) is the main cytosolic enzyme that converts the citrate exported from mitochondria by the SLC25A1 carrier in Acetyl Coenzyme A (acetyl-CoA) and oxaloacetate.
CENCI, GIOVANNI +6 more
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Inhibitors of Pyruvate Carboxylase [PDF]
, 2010 This review aims to discuss the varied types of inhibitors of biotin-dependent carboxylases, with an emphasis on the inhibitors of pyruvate carboxylase.
Attwood, Paul V. +2 more
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Nature Communications, 2023 The molecular mechanisms connecting cellular metabolism with differentiation remain poorly understood. Here, we find that metabolic signals contribute to stem cell differentiation and germline homeostasis during Drosophila melanogaster spermatogenesis ...
Charlotte M. François +4 more
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Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus
Frontiers in Microbiology, 2021 Vibrio vulnificus is a zoonotic bacterium that is capable of causing highly lethal diseases in humans; this pathogen is responsible for 95% of all seafood-related deaths in the United States. Arylamine N-acetyltransferases (NAT, E.C.
Xinning Liu +15 more
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Allosteric Regulation Alters Carrier Domain Translocation in Pyruvate Carboxylase [PDF]
, 2018 Pyruvate carboxylase (PC) catalyzes the ATP-dependent carboxylation of pyruvate to oxaloacetate. The reaction occurs in two separate catalytic domains, coupled by the long-range translocation of a biotinylated carrier domain (BCCP). Here, we use a series
Budelier, Melissa M. +3 more
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Dynamic-tuning yeast storage carbohydrate improves the production of acetyl-CoA-derived chemicals
iScience, 2023 Summary: Acetyl-coenzyme A (Acetyl-CoA) and malonyl-coenzyme A (malonyl-CoA) are important precursors for producing various chemicals, and their availability affects the production of their downstream chemicals.
Chenxi Qiu +4 more
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Remnants of an ancient metabolism without phosphate [PDF]
, 2017 Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E. +3 more
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Corrins and the Acetyl-CoA Path of Autotrophic Fixation of Carbon Dioxide in Bacteria
CHIMIA, 1988 Autotrophic fixation of carbon dioxide in bacteria proceedes not only via the well-known «Calvin cycle», but also via the recently established «acetyl-coenzyme A pathway», meanwhile found to be widely distributed in bacterial anaerobes.
Bernhard Kräutler
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