Results 11 to 20 of about 49,846 (154)

Dynamic-tuning yeast storage carbohydrate improves the production of acetyl-CoA-derived chemicals

open access: yesiScience, 2023
Summary: Acetyl-coenzyme A (Acetyl-CoA) and malonyl-coenzyme A (malonyl-CoA) are important precursors for producing various chemicals, and their availability affects the production of their downstream chemicals.
Chenxi Qiu   +4 more
doaj   +1 more source

The Roles of Coenzyme A Binding Pocket Residues in Short and Medium Chain Acyl-CoA Synthetases

open access: yesLife, 2023
Short- and medium-chain acyl-CoA synthetases catalyze similar two-step reactions in which acyl substrate and ATP bind to form an enzyme-bound acyl-adenylate, then CoA binds for formation of the acyl-CoA product.
Yu Meng   +3 more
doaj   +1 more source

Who Rules the Cell? An Epi-Tale of Histone, DNA, RNA, and the Metabolic Deep State

open access: yesFrontiers in Plant Science, 2020
Epigenetics refers to the mode of inheritance independent of mutational changes in the DNA. Early evidence has revealed methylation, acetylation, and phosphorylation of histones, as well as methylation of DNA as part of the underlying mechanisms.
Jeffrey Leung, Valérie Gaudin
doaj   +1 more source

Metabolic Engineering Design Strategies for Increasing Acetyl-CoA Flux

open access: yesMetabolites, 2020
Acetyl-CoA is a key metabolite precursor for the biosynthesis of lipids, polyketides, isoprenoids, amino acids, and numerous other bioproducts which are used in various industries.
Jason T. Ku, Arvin Y. Chen, Ethan I. Lan
doaj   +1 more source

Insoluble Dietary Fiber from Soybean Residue (Okara) Exerts Anti-Obesity Effects by Promoting Hepatic Mitochondrial Fatty Acid Oxidation

open access: yesFoods, 2023
Numerous investigations have shown that insoluble dietary fiber (IDF) has a potentially positive effect on obesity due to a high-fat diet (HFD). Our previous findings based on proteomic data revealed that high-purity IDF from soybean residue (okara ...
Jiarui Zhang   +7 more
doaj   +1 more source

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A [PDF]

open access: yesMolecular Cell, 2014
Acetyl-coenzyme A (AcCoA) is a major integrator of the nutritional status at the crossroads of fat, sugar, and protein catabolism. Here we show that nutrient starvation causes rapid depletion of AcCoA. AcCoA depletion entailed the commensurate reduction in the overall acetylation of cytoplasmic proteins, as well as the induction of autophagy, a ...
Mariño G   +31 more
openaire   +4 more sources

Acetyl-coenzyme A Synthetase (Acs) Assay

open access: yesBio-Protocol, 2012
Acetyl-coenzyme A synthethase (Acs, E.C.6.2.1.1) is an acetate activating enzyme widely represented in nature from bacteria to human. Its function is important for cellular catabolism, especially in order to support microbial growth at low concentrations
Sara Castaño Cerezo   +2 more
doaj   +1 more source

De novo fatty acid synthesis and elongation of fatty acids by subcellular fractions of lung

open access: yesJournal of Lipid Research, 1971
Fatty acid synthesis by subcellular fractions of rabbit lung was studied by measuring the incorporation of either radioactive acetyl coenzyme A or malonyl coenzyme A into long-chain fatty acids.
HARVEY SCHILLER, KLAUS BENSCH
doaj   +1 more source

Geographic Distribution of Ryegrass Resistent to the Clethodim Herbicide in Rio Grande do Sul1 [PDF]

open access: yesPlanta Daninha, 2016
Ryegrass is a weed of annual cycle that is present in winter crops, in orchards and vineyards of the South region of Brazil. The species is normally controlled by the glyphosate herbicide, but the continuous use of this product caused the selection of ...
L. VARGAS   +3 more
doaj   +2 more sources

Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model

open access: yesNutrition Journal, 2010
Background/Aims Matrix Metalloproteinases 2 is a key molecule in cellular invasion and metastasis. Mitochondrial ROS has been established as a mediator of MMP activity. Coenzyme Q10 contributes to intracellular ROS regulation.
Mirmiranpour Hossein   +6 more
doaj   +1 more source

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