Results 21 to 30 of about 50,102 (223)

Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A [PDF]

open access: yesCell Metabolism, 2019
David Rubinsztein   +2 more
exaly   +2 more sources

From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2. [PDF]

open access: yesPLoS ONE, 2014
Acetyl Coenzyme A-dependent N-, O- and N,O-acetylation of aromatic amines and hydrazines by arylamine N-acetyltransferases is well characterised. Here, we describe experiments demonstrating that human arylamine N-acetyltransferase Type 1 and its murine ...
Nicola Laurieri   +7 more
doaj   +1 more source

Dynamic-tuning yeast storage carbohydrate improves the production of acetyl-CoA-derived chemicals

open access: yesiScience, 2023
Summary: Acetyl-coenzyme A (Acetyl-CoA) and malonyl-coenzyme A (malonyl-CoA) are important precursors for producing various chemicals, and their availability affects the production of their downstream chemicals.
Chenxi Qiu   +4 more
doaj   +1 more source

The Roles of Coenzyme A Binding Pocket Residues in Short and Medium Chain Acyl-CoA Synthetases

open access: yesLife, 2023
Short- and medium-chain acyl-CoA synthetases catalyze similar two-step reactions in which acyl substrate and ATP bind to form an enzyme-bound acyl-adenylate, then CoA binds for formation of the acyl-CoA product.
Yu Meng   +3 more
doaj   +1 more source

Who Rules the Cell? An Epi-Tale of Histone, DNA, RNA, and the Metabolic Deep State

open access: yesFrontiers in Plant Science, 2020
Epigenetics refers to the mode of inheritance independent of mutational changes in the DNA. Early evidence has revealed methylation, acetylation, and phosphorylation of histones, as well as methylation of DNA as part of the underlying mechanisms.
Jeffrey Leung, Valérie Gaudin
doaj   +1 more source

Metabolic Engineering Design Strategies for Increasing Acetyl-CoA Flux

open access: yesMetabolites, 2020
Acetyl-CoA is a key metabolite precursor for the biosynthesis of lipids, polyketides, isoprenoids, amino acids, and numerous other bioproducts which are used in various industries.
Jason T. Ku, Arvin Y. Chen, Ethan I. Lan
doaj   +1 more source

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A [PDF]

open access: yesMolecular Cell, 2014
Acetyl-coenzyme A (AcCoA) is a major integrator of the nutritional status at the crossroads of fat, sugar, and protein catabolism. Here we show that nutrient starvation causes rapid depletion of AcCoA. AcCoA depletion entailed the commensurate reduction in the overall acetylation of cytoplasmic proteins, as well as the induction of autophagy, a ...
Mariño G   +31 more
openaire   +4 more sources

Acetyl-coenzyme A Synthetase (Acs) Assay

open access: yesBio-Protocol, 2012
Acetyl-coenzyme A synthethase (Acs, E.C.6.2.1.1) is an acetate activating enzyme widely represented in nature from bacteria to human. Its function is important for cellular catabolism, especially in order to support microbial growth at low concentrations
Sara Castaño Cerezo   +2 more
doaj   +1 more source

Insoluble Dietary Fiber from Soybean Residue (Okara) Exerts Anti-Obesity Effects by Promoting Hepatic Mitochondrial Fatty Acid Oxidation

open access: yesFoods, 2023
Numerous investigations have shown that insoluble dietary fiber (IDF) has a potentially positive effect on obesity due to a high-fat diet (HFD). Our previous findings based on proteomic data revealed that high-purity IDF from soybean residue (okara ...
Jiarui Zhang   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy