Results 31 to 40 of about 2,632,092 (318)
Foods, 2023 Numerous investigations have shown that insoluble dietary fiber (IDF) has a potentially positive effect on obesity due to a high-fat diet (HFD). Our previous findings based on proteomic data revealed that high-purity IDF from soybean residue (okara ...
Jiarui Zhang +7 more
doaj +1 more source
Discovery of the acetyl cation, CH3CO+, in space and in the laboratory [PDF]
A&A 646, L7 (2021), 2021 Using the Yebes 40m and IRAM 30m radiotelescopes, we detected two series of harmonically related lines in space that can be fitted to a symmetric rotor. The lines have been seen towards the cold dense cores TMC-1, L483, L1527, and L1544. High level of theory ab initio calculations indicate that the best possible candidate is the acetyl cation, CH3CO ...
arxiv +1 more source
Metabolic Engineering Design Strategies for Increasing Acetyl-CoA Flux
Metabolites, 2020 Acetyl-CoA is a key metabolite precursor for the biosynthesis of lipids, polyketides, isoprenoids, amino acids, and numerous other bioproducts which are used in various industries.
Jason T. Ku, Arvin Y. Chen, Ethan I. Lan
doaj +1 more source
Geographic Distribution of Ryegrass Resistent to the Clethodim Herbicide in Rio Grande do Sul1 [PDF]
Planta Daninha, 2016 Ryegrass is a weed of annual cycle that is present in winter crops, in orchards and vineyards of the South region of Brazil. The species is normally controlled by the glyphosate herbicide, but the continuous use of this product caused the selection of ...
L. VARGAS +3 more
doaj +2 more sources
Effects of ligand binding on the energy landscape of acyl-CoA-binding protein [PDF]
Biophys. J. 119 (2020) 1821-1832, 2021 Binding of ligands is often crucial for function yet the effects of ligand binding on the mechanical stability and energy landscape of proteins are incompletely understood. Here we use a combination of single-molecule optical tweezers and MD simulations to investigate the effect of ligand binding on the energy landscape of acyl-coenzyme A (CoA) binding
arxiv +1 more source
Prebiotic Vitamin B$_3$ Synthesis in Carbonaceous Planetesimals [PDF]
ChemPlusChem 2023, e202300508, 2023 Aqueous chemistry within carbonaceous planetesimals is promising for synthesizing prebiotic organic matter essential to all life. Meteorites derived from these planetesimals delivered these life building blocks to the early Earth, potentially facilitating the origins of life.
arxiv +1 more source
Time‐resolved multiparameter analytics on a cell‐free production platform for acyl‐CoA precursors
Analytical Science Advances, Volume 3, Issue 11-12, Page 289-296, December 2022., 2022 Abstract Cell‐free biosynthesis is emerging as a very attractive alternative for the production of market‐relevant molecules. The free combination of enzymes, regardless of where they are isolated from, raises the possibility to build more efficient synthetic routes but at the same time leads to higher complexity regarding the analysis of the different
Dominic Maehler +7 more
wiley +1 more source
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-depleted Murine Embryonic Stem Cells [PDF]
PLoS Comp Bio, 2010 Dec 16;6(12):e1001034, 2010 Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency and lineage specification are poorly understood, but recent results point to a key role for epigenetic mechanisms.
arxiv +1 more source
Lipid metabolism in pancreatic cancer: emerging roles and potential targets
Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022 Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin +6 more
wiley +1 more source
Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model
Nutrition Journal, 2010 Background/Aims Matrix Metalloproteinases 2 is a key molecule in cellular invasion and metastasis. Mitochondrial ROS has been established as a mediator of MMP activity. Coenzyme Q10 contributes to intracellular ROS regulation.
Mirmiranpour Hossein +6 more
doaj +1 more source