Results 41 to 50 of about 9,200 (244)
Transplacental exposure to AZT induces adverse neurochemical and behavioral effects in a mouse model: protection by L-acetylcarnitine. [PDF]
PLoS ONE, 2013 Maternal-fetal HIV-1 transmission can be prevented by administration of AZT, alone or in combination with other antiretroviral drugs to pregnant HIV-1-infected women and their newborns. In spite of the benefits deriving from this life-saving prophylactic
Anna Rita Zuena +12 more
doaj +1 more source
Andrologia, 2019 Carnitine is essential for energy metabolism and spermatozoa maturation. Combining L‐carnitine and L‐acetylcarnitine with micronutrients has been investigated as a treatment for infertility in men.
S. Micic +7 more
semanticscholar +1 more source
Does skeletal muscle carnitine availability influence fuel selection during exercise? [PDF]
, 2018 This is the author accepted manuscript. The final version is available from Cambridge University Press via the DOI in this record.Fat and carbohydrate are the major fuel sources utilised for oxidative, mitochondrial ATP resynthesis during human skeletal ...
Stephens, FB
core +1 more source
Metabolites, 2022 Diagnosing the cause of fatal intoxication by antipsychotic agents is an important task in forensic practice. In the 2020 Annual Report of the American Association of Poison Control Centers, among 40 deaths caused by antipsychotics, 21 cases were ...
Rui Bai +7 more
doaj +1 more source
Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. [PDF]
, 2016 Cardiac dysfunction is often associated with a shift in substrate preference for ATP production. Hyperpolarized (HP) (13)C magnetic resonance spectroscopy (MRS) has the unique ability to detect real-time metabolic changes in vivo due to its high ...
Bastiaansen, J.A. +2 more
core +2 more sources
Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation [PDF]
Epigenetics, 2009 Dynamic acetylation and deacetylation of nuclear histones is essential for regulating the access of chromosomal DNA to transcriptional machinery. The source of acetyl-CoA for histone acetylation in mammalian cell nuclei is not clearly known. We show that acetylcarnitine formed in mitochondria, is transported into cytosol by carnitine/acylcarnitine ...
Padma, Madiraju +3 more
openaire +2 more sources
Chemoreactomic analysis of citrulline malate molecules
Неврология, нейропсихиатрия, психосоматика, 2017 Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
I. Yu. Torshin +4 more
doaj +1 more source
Frontiers in Veterinary Science, 2023 The Liang guang Small-spotted pig is a well-known Chinese indigenous pig that is valued for its exceptional meat quality. However, the Liang guang Small-spotted pig has a lower semen storage capacity, shorter storage time and worse semen quality compared
Zhili Li +8 more
doaj +1 more source
Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance [PDF]
, 2018 The pattern of metabolic reprogramming in chronic hypoxia shares similarities with that following myocardial infarction or hypertrophy, however the response of the chronically hypoxic heart to subsequent acute injury, and the role of metabolism is not ...
Allard +58 more
core +2 more sources
, 2018 The incidence of Type 2 diabetes is on the rise. This disease is characterised by the body not responding effectively to the hormone insulin (i.e. insulin resistance) and a reduced ability to switch between fat burning and glucose burning. As a result, blood glucose levels rise cannot be maintained properly and will therefore rise. By means of magnetic
openaire +2 more sources