Results 11 to 20 of about 35,074 (278)

A synopsis of eukaryotic N^α-terminal acetyltransferases: nomenclature, subunits and substrates [PDF]

BMC Proceedings, 2009
We have introduced a consistent nomenclature for the various subunits of the NatA-NatE N-terminal acetyltransferases from yeast, humans and other eukaryotes.
Polevoda Bogdan, Arnesen Thomas, Sherman Fred   +2 more
doaj   +3 more sources

The K46 and K5 capsular polysaccharides produced by Acinetobacter baumannii NIPH 329 and SDF have related structures and the side-chain non-ulosonic acids are 4-O-acetylated by phage-encoded O-acetyltransferases.

PLoS ONE, 2019
Acinetobacter baumannii isolate NIPH 329 carries a novel capsular polysaccharide (CPS) gene cluster, designated KL46, that is closely related to the KL5 locus in A.
Johanna J Kenyon, Nikolay P Arbatsky, Mikhail M Shneider, Anastasiya V Popova, Andrei S Dmitrenok, Anastasiya A Kasimova, Alexander S Shashkov, Ruth M Hall, Yuriy A Knirel   +8 more
doaj   +2 more sources

Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases. [PDF]

PLoS Computational Biology, 2020
The enzymes of the GCN5-related N-acetyltransferase (GNAT) superfamily count more than 870 000 members through all kingdoms of life and share the same structural fold.
Bojan Krtenic, Adrian Drazic, Thomas Arnesen, Nathalie Reuter   +3 more
doaj   +2 more sources

Mycobacterial Aminoglycoside Acetyltransferases: A Little of Drug Resistance, and a Lot of Other Roles [PDF]

Frontiers in Microbiology, 2019
Aminoglycoside acetyltransferases are important determinants of resistance to aminoglycoside antibiotics in most bacterial genera. In mycobacteria, however, aminoglycoside acetyltransferases contribute only partially to aminoglycoside susceptibility ...
Fernando Sanz-García, Ernesto Anoz-Carbonell, Ernesto Anoz-Carbonell, Esther Pérez-Herrán, Carlos Martín, Carlos Martín, Ainhoa Lucía, Ainhoa Lucía, Liliana Rodrigues, Liliana Rodrigues, Liliana Rodrigues, José A. Aínsa, José A. Aínsa   +12 more
doaj   +4 more sources

Plant Cell Wall Polysaccharide O-Acetyltransferases

Plants
Plant cell walls are largely composed of polysaccharide polymers, including cellulose, hemicelluloses (xyloglucan, xylan, mannan, and mixed-linkage β-1,3/1,4-glucan), and pectins.
Ruiqin Zhong, Dayong Zhou, Lirong Chen, John P. Rose, Bi-Cheng Wang, Zheng-Hua Ye   +5 more
doaj   +2 more sources

Exploring the role of N-acetyltransferases in diseases: a focus on N-acetyltransferase 9 in neurodegeneration

Neural Regeneration Research
Acetyltransferases, required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.
Prajakta Deshpande, Anuradha Venkatakrishnan Chimata, Amit Singh   +2 more
doaj   +2 more sources

A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases

Cell Reports
Summary: Histone acetylation is a critical modification that regulates gene expression by modulating chromatin structure and function. Histone acetyltransferases are essential for maintaining acetylation homeostasis, and the disruption of this balance ...
Xuekun Fu, Xu Yang, Jie Huang, Yuhong Huang, Patrick Ryan Potts, Chao Liang   +5 more
doaj   +2 more sources

Cofactor Analogues as Active Site Probes in Lysine Acetyltransferases [PDF]

, 2019
Lysine acetyltransferases (KATs, also termed histone acetyltransferases, HATs) catalyze the acetylation of substrate lysine residues by employing the cofactor acetyl-coenzyme A (AcCoA), thereby providing a dynamic control mechanism of protein function ...
Daumantas Matulis (308173), Asifa Akhtar (158014), Tobias Rumpf (169559), Manfred Jung (26925), Vaida Linkuviene (6426962), Roman P. Simon (6426959)   +5 more
core   +5 more sources

Characterisation of Lipopolysaccharide O-antigen Acetyltransferases in the Bacterium Salmonella [PDF]

, 2015
Characterisation of Lipopolysaccharide O-antigen Acetyltransferases in the Bacterium Salmonella Reyme Herman MSc by Research University of York Biology March 2015 Abstract Bacteria are known to possess various modifications on the ...
Herman, Reyme
core   +6 more sources

Pyrido- and benzisothiazolones as inhibitors of histone acetyltransferases (HATs) [PDF]

, 2014
Histone acetyltransferases (HATs) are interesting targets for the treatment of cancer and HIV infections but reports on selective inhibitors are very limited.
Robaa, Dina, Jung, Manfred, Hoffmann, Inga, Furdas, Silviya Dimitrova   +3 more
core   +2 more sources