Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Out‐of‐Equilibrium Supramolecular Assembly Sustained by Photocatalysis
Catalysis sustains structure: A Pt(II) supramolecular photocatalyst persists in a far‐from‐equilibrium state only as long as it remains photocatalytically active. Without ongoing catalytic activity, the system irreversibly relaxes into a thermodynamically stable but inactive state (PtB). Catalysis is essential for sustaining its structure.
E. Pelorosso +5 more
wiley +2 more sources
Influence of synthetic derivatives of cytokinin and auxin on yield and quality of rainy season guava (Psidium guajava L.) cv. Shweta. [PDF]
Mourya A +4 more
europepmc +1 more source
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam +8 more
wiley +1 more source
A Review of Artificial Diets for Aphids (Hemiptera: Aphididae). [PDF]
Gao R, Zeng Q, Zhu M, Ren Z, Xue K.
europepmc +1 more source
Mitigating cobalt toxicity in linseed (Linum usitatissimum L.): the role of ascorbic acid in enhancing pigments formation, antioxidant defense and gene expression. [PDF]
Asif H +12 more
europepmc +1 more source
Effect of Ultrasound Pretreatment Combined with Magnetic Field-Assisted Freezing on Bioactive Compounds and Antioxidant Capacity of Blueberry. [PDF]
You K, Xiong X, Wang Z, Li Q, Cao X.
europepmc +1 more source
Influence of soil health on tomato sensory quality: a PRISMA-based systematic review. [PDF]
Beyuo J +5 more
europepmc +1 more source
ABSTRACT In oil‐in‐water emulsions, lipid oxidation begins at the interface between the two phases. One strategy to slow down this process is to place antioxidants at the interface, where they can directly block oxidative reactions. This study explored that idea by conjugating soluble faba bean protein with tannic acid using the free‐radical grafting ...
Shahrzad Sharifimehr, Supratim Ghosh
wiley +1 more source

