Results 11 to 20 of about 1,631 (150)

Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities. [PDF]

Chem Biodivers
This review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
Castro JWG, Souza GGO, da Costa JGM, Rodrigues FFG.   +3 more
europepmc   +2 more sources

Tuning the Excited State Character of Amine/Carbonyl Thermally Activated Delayed Fluorescence Emitters with Ring Fusion. [PDF]

Chemistry
Ring fusion in MR‐TADF emitters can affect the charge transfer excited state and therefore the photophysical properties. Here we investigate the effect of ring fusion in two structurally similar molecules to identify the advantages and disadvantages of this strategy.
Kalab T, Gogoulis AT, Patrick BO, Hudson ZM.   +3 more
europepmc   +2 more sources

Through-space interaction enables simultaneous enhancements of <i>k</i> _<i>r</i> and <i>k</i> _RISC in highly efficient spiro-acridine based thermally activated delayed fluorescence emitter with acridone acceptor. [PDF]

Smart Mol
Intramolecular through‐space interaction is designed for the first time in a thermally activated delayed fluorescence emitter to pull the appropriate rotation of the acridine donor to deviate from the perpendicular orientation, which solves the common problem of insufficient FMO overlap to simultaneously enhance the radiation transition and reverse ...
Mei Y, Liu D, Li J, Xu M, Wang J, Jin J, Xie L, Wan H.   +7 more
europepmc   +2 more sources

Synthesis of acridone derivatives via heterologous expression of a plant type III polyketide synthase in Escherichia coli

Microbial Cell Factories, 2020
Background Acridone alkaloids are heterocyclic compounds that exhibit a broad-range of pharmaceutical and chemotherapeutic activities, including anticancer, antiviral, anti-inflammatory, antimalarial, and antimicrobial effects. Certain plant species such
Gyu-Sik Choi, Hye Jeong Choo, Bong-Gyu Kim, Joong-Hoon Ahn   +3 more
doaj   +1 more source

Xanthone-1,2,4-triazine and Acridone-1,2,4-triazine Conjugates: Synthesis and Anticancer Activity

Pharmaceuticals, 2023
A total of 21 novel xanthone and acridone derivatives were synthesized using the reactions of 1,2,4-triazine derivatives with 1-hydroxy-3-methoxy-10-methylacridone, 1,3-dimethoxy-, and 1,3-dihydroxanthone, followed by optional dihydrotiazine ring ...
Sougata Santra, Ainur D. Sharapov, Ramil F. Fatykhov, Anastasya P. Potapova, Igor A. Khalymbadzha, Maria I. Valieva, Dmitry S. Kopchuk, Grigory V. Zyryanov, Alexander S. Bunev, Vsevolod V. Melekhin, Vasiliy S. Gaviko, Andrey A. Zonov   +11 more
doaj   +1 more source

Acridone derivative 8a induces oxidative stress-mediated apoptosis in CCRF-CEM leukemia cells: application of metabolomics in mechanistic studies of antitumor agents. [PDF]

PLoS ONE, 2013
A new acridone derivative, 2-aminoacetamido-10-(3, 5-dimethoxy)-benzyl-9(10H)-acridone hydrochloride (named 8a) synthesized in our lab shows potent antitumor activity, but the mechanism of action remains unclear.
Yini Wang, Dan Gao, Zhe Chen, Shangfu Li, Chunmei Gao, Deliang Cao, Feng Liu, Hongxia Liu, Yuyang Jiang   +8 more
doaj   +1 more source

Design and Synthesis of New Acridone-Based Nitric Oxide Fluorescent Probe

Molecules, 2021
Nitric oxide (NO) is an important signaling molecule involved in a wide range of physiological and pathological processes. Fluorescent imaging is a useful tool for monitoring NO concentration, which could be essential in various biological and ...
Mikhail Panfilov, Darya Chernova, Irina Khalfina, Alexander Moskalensky, Aleksey Vorob’ev   +4 more
doaj   +1 more source

Fermentative N-Methylanthranilate Production by Engineered Corynebacterium glutamicum

Microorganisms, 2020
The N-functionalized amino acid N-methylanthranilate is an important precursor for bioactive compounds such as anticancer acridone alkaloids, the antinociceptive alkaloid O-isopropyl N-methylanthranilate, the flavor compound O-methyl-N-methylanthranilate,
Tatjana Walter, Nour Al Medani, Arthur Burgardt, Katarina Cankar, Lenny Ferrer, Anastasia Kerbs, Jin-Ho Lee, Melanie Mindt, Joe Max Risse, Volker F. Wendisch   +9 more
doaj   +1 more source

Acridone Derivatives from Atalantia monophyla Inhibited Cancer Cell Proliferation through ERK Pathway

Molecules, 2022
The present study aimed to investigate the effect of acridone alkaloids on cancer cell lines and elucidate the underlying molecular mechanisms. The ten acridone alkaloids from Atalantia monophyla were screened for cytotoxicity against LNCaP cell lines by
Wen-Yong Gao, Chantana Boonyarat, Pitchayakarn Takomthong, Kusawadee Plekratoke, Yoshihiro Hayakawa, Chavi Yenjai, Rawiwun Kaewamatawong, Suchada Chaiwiwatrakul, Pornthip Waiwut   +8 more
doaj   +1 more source

RETRACTED: An acridone-derived fluorescent off-on probe for detection and in vivo imaging of nitroreductase

Frontiers in Materials, 2023
Understanding the functions of enzymes in various physiological processes is important, but the design of signaling probes for fast analysis of enzymatic activity is particularly challenging.
Meicen Liu, Guanyu Chen, Guanyu Chen, Lilan Xu, Lilan Xu, Tingting Chen, Tingting Chen, Wenqian Chen, Wenqian Chen, Jinghua Chen, Jinghua Chen, Xi Zhang   +11 more
doaj   +1 more source