Results 11 to 20 of about 24,732 (236)

JAGGED1 modulates bull spermatozoa acrosome reaction and fertilization [PDF]

open access: yesReproduction and Fertility
To acquire fertilizing ability, mammalian spermatozoa (SPZ) must undergo acrosome reaction, which is associated with protein remodeling and relocation. Previous studies showed that Notch ligand JAGGED1 is relocated from the apical to the post-equatorial ...
Patrícia Diniz   +5 more
doaj   +2 more sources

Regulating the acrosome reaction

open access: yesThe International Journal of Developmental Biology, 2008
The acrosome reaction is a secretory event that must be completed by the sperm of many animal species prior to fusion with eggs. In mammals, exocytosis in triggered by ZP3, a glycoprotein component of the egg pellucida, following gamete contact. ZP3 promotes a sustained influx of Ca2+ into sperm that is necessary for the acrosome reaction.
Florman, Harvey M.   +2 more
openaire   +5 more sources

Mechanism of Acrosome Biogenesis in Mammals

open access: yesFrontiers in Cell and Developmental Biology, 2019
During sexual reproduction, two haploid gametes fuse to form the zygote, and the acrosome is essential to this fusion process (fertilization) in animals.
Muhammad Babar Khawar   +1 more
exaly   +3 more sources

The acrosome of eutherian mammals

open access: yesCell and Tissue Research, 2015
The acrosome is not just a bag of enzymes, most of which, if not all, are singly non-essential for sperm-oocyte interaction. The Golgi-derived acrosomal cap reveals some extraordinary development and structure particularities. The acrosome of eutherian spermatozoa basically consists of two parts, the anterior and equatorial segments; the present review
Fléchon, Jacques-Edmond
openaire   +3 more sources

Effects of Caffeic Acid Supplementation on Human Sperm Against In Vitro-Induced Oxidative Stress: Nrf2 Molecular Pathway [PDF]

open access: yesAntioxidants
Oxidative stress (OS) is a major cause of defective sperm function. During laboratory handling, gametes are exposed to OS, potentially mitigated by in vitro antioxidant supplementation.
Laura Liguori   +4 more
doaj   +2 more sources

Novel HYDIN variants associated with male infertility in two Chinese families

open access: yesFrontiers in Endocrinology, 2023
IntroductionInfertility is a major disease affecting human life and health, among which male factors account for about half. Asthenoteratozoospermia accounts for the majority of male infertility.
Hui Yu   +52 more
doaj   +1 more source

Molecular Analysis of DPY19L2, PICK1 and SPATA16 in Italian Unrelated Globozoospermic Men

open access: yesLife, 2021
This study aims to evaluate genetic contribution and sperm DNA fragmentation (SDF) in a cohort of 18 unrelated globozoospermic Italian men (Group G). Semen samples were assessed according to the WHO 2010 Laboratory Manual and compared with 31 fertile ...
Fabiana Faja   +7 more
doaj   +1 more source

Semen abnormalities in patients with human papillomavirusassociated infertility detected by electron transmission microscopy

open access: yesВестник урологии, 2023
Introduction. Recent research have suggested a link between human papillomavirus (HPV) and declining male fertility.Objective. To study the pathomorphological changes in ejaculate of patients with human papillomavirus-associated infertility using ...
Kh. S. Ibishev   +4 more
doaj   +1 more source

Differential Expression and Localization of EHBP1L1 during the First Wave of Rat Spermatogenesis Suggest Its Involvement in Acrosome Biogenesis

open access: yesBiomedicines, 2022
The identification and characterization of new proteins involved in spermatogenesis is fundamental, considering that good-quality gametes are basic in ensuring proper reproduction.
Massimo Venditti, Sergio Minucci
doaj   +1 more source

Hypoosmotic Test Combined with Coomassie Blue Staining in Llama Sperm [PDF]

open access: yesSPERMOVA, 2018
To stablish sperm fertilization capacity membrane integrity and functionality are important characteristics to determine. The objectives of the present study were: 1) to evaluate the functionality of the plasma membrane over time by the hypoosmotic test (
M,I, Carretero   +3 more
doaj   +1 more source

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