Results 31 to 40 of about 26,981 (241)
Ubiquitination Regulates the Morphogenesis and Function of Sperm Organelles
It is now understood that protein ubiquitination has diverse cellular functions in eukaryotes. The molecular mechanism and physiological significance of ubiquitin-mediated processes have been extensively studied in yeast, Drosophila and mammalian somatic
Nobuhiro Nakamura
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A mechanism for differential release of acrosomal enzymes during the acrosome reaction [PDF]
To study the organization of fertilization enzymes in the sperm acrosome, we isolated and characterized two physicochemically distinct acrosomal fractions of guinea-pig spermatozoa. A soluble fraction contained the 25,000-Mr acrosomal autoantigen, AA1, and most of the acrosomal hyaluronidase and dipeptidyl peptidase II activity. A particulate fraction,
D M, Hardy +3 more
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Wild African Lion Panthera leo populations are decreasing due to inbreeding and reduced genetic variability. Thus, the use of assisted reproduction in the species could one day become essential.
Thiesa Butterby Soler Barbosa +7 more
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SEQUENTIAL RELEASE OF ACROSOMAL MEMBRANES AND ACROSOMAL ENZYMES OF RAM SPERMATOZOA [PDF]
Summary. A method involving the treatment of ram spermatozoa with MgCl2 followed by Hyamine 2389 and Triton X-100 is described, which gave selective removal of the acrosomal membranes and acrosomal enzymes. The effect on the individual membranes of ram spermatozoa was evaluated by electron microscopy.
P N, Srivastava +3 more
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Plasma membrane-Acrosome-Mitochondria
Raw data of sperm plasma membrane, acrosome, mitochondria, and healthy sperm, and the results of statistical ...
Vui Nguyen (6833942)
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Mammalian sperm acrosome contains several glycohydrolases thought to aid in the dispersion and digestion of vestments surrounding the egg. In this study, we have used multiple approaches to examine the origin of acrosome-associated glycohdyrdolases ...
Abou-Haila Aida, Tulsiani Daulat
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Globozoospermia is a form of male infertility characterized by spermatozoa with spherical heads lacking acrosomes. The aim of this study was to evaluate ultrastructural and molecular defects in different types of globozoospermia.
Elizaveta Bragina +14 more
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Fertilization is an intricate cascade of events that irreversibly alter the participating male and female gamete and ultimately lead to the union of paternal and maternal genomes in the zygote.
P. Sutovsky
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Immunofluorescence detection of the acrosome.
(a) Immunofluorescence detection of the acrosome with PNA (green) was performed to illustrate and quantify the sperm acrosome abnormalities. Hoechst was used to nuclei staining (blue); bar = 20μm.
Ling Chen (25698) +7 more
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Human globozoospermia‐related genes and their role in acrosome biogenesis
The mammalian acrosome is a secretory vesicle attached to the sperm nucleus whose fusion with the overlying plasma membrane is required to achieve fertilization.
Moreno, Ricardo D., Ricardo D. Moreno
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